Down-Regulation of Collagen Hydroxylation in Colorectal Liver Metastasis
Collagen is significantly upregulated in colorectal liver metastasis (CRLM) compared to liver tissue. Expression levels of specific collagen types in CRLM resemble those in colorectal cancer (CRC) and colon tissue.
Nick A. van Huizen +6 more
doaj +1 more source
Does dietary intake of acrylamide affect hydroxyproline levels? An animal study
Acrylamide is a chemical that occurs due to high temperatures during cooking. It consists of an amino acid found in foods and sugars. Studies have shown that cancer formation occurs within the scope of oxidant reagents and DNA damage due to exposure to ...
Tugba Agbektas +5 more
doaj +1 more source
Fish Collagen Surgical Compress Repairing Characteristics on Wound Healing Process In Vivo
The development of biomaterials with the potential to accelerate wound healing is a great challenge in biomedicine. In this study, four types of samples including pepsin soluble collagen sponge (PCS), acid soluble collagen sponge (ACS), bovine collagen ...
Jingjing Chen +8 more
doaj +1 more source
Bone Turnover Markers: An Emerging Tool to Detect Primary Osteoporosis [PDF]
Introduction: Osteoporosis is a global health problem, asymptomatic and noticed only after a fracture. Ten years after the cessation of ovarian function due to hormonal imbalance, women show an accelerated phase of reduction in bone mass known as ...
Mayur Rai +3 more
doaj +1 more source
The new insight into the role of hydroxyproline in metabolism of cancer cells
Although the role of proline (Pro) in regulatory mechanisms of cell metabolism is well recognized, the interest in metabolic significance of hydroxyproline (Hyp) has received little attention.
Magda Chalecka +3 more
doaj +1 more source
Connective tissue dysplasia as a trigger of pyelonephritis severity in children
Background. In recent decades, more and more attention of practitioners is attracted to the role of pathology of various organs and systems of the human body associated with connective tissue dysplasia, which leads to chronicity and relapse of the ...
N.S. Lukyanenko +3 more
doaj +1 more source
A bienzyme electrochemical biosensor for the detection of collagen l-hydroxyproline
l-hydroxyproline (l-Hyp: trans-4-hydroxy-l-proline) is commonly found at high concentrations in connective tissue proteins such as collagen. It is a remarkably useful molecular marker because variation in the level of l-Hyp is associated with various ...
Hiroaki Sakamoto +6 more
doaj +1 more source
CBP/β-Catenin Signaling in Hepatocytes Plays Pivotal Roles in MMP-7-Mediated Liver Fibrosis in a Metabolic Dysfunction-Associated Steatohepatitis Mouse Model. [PDF]
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Imamura J +5 more
europepmc +2 more sources
STEREOISOMERS OF HYDROXYPROLINE
Hydroxy-L-proline was first isolated by Fischer in 1902 from a hydrolysate of gelatin (l).l The synthesis and determination of the structure were reported by Leuchs and coworkers (5--g), and, in 1919, the separation of the two racemic stereoisomers and the resolution of each racemate through mixtures of quinine with the corresponding N-phenylisocyanate
D S, ROBINSON, J P, GREENSTEIN
openaire +2 more sources
Introduction: This research aimed to examine and compare the effect of two calcium silicate sealers with AH plus resin sealer on collagen extraction and surface collagen degradation of dog's root dentin, using different irrigants.
Samah Mohammad Ismail +3 more
doaj +1 more source

