Results 121 to 130 of about 74,894 (279)

Effect of Red Blood Cell Transfusion on Inflammatory and Angiogenic Pathways in Patients With Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 4, Page 718-727, April 2026.
ABSTRACT Sickle cell disease (SCD) is a chronic inflammatory state, characterized by increased plasma values of inflammatory and angiogenic proteins. Although red blood cell (RBC) transfusion is known to have immunomodulatory effects in other conditions, its potential effects on the inflammatory state in SCD remain largely unknown.
Lydian A. de Ligt, Sanjay R. Thakoerdin, Maud Zwolsman, Gaby Stegemann, Hanke Matlung, Taco W. Kuijpers, Bart J. Biemond, Karin Fijnvandraat, Robin van Bruggen, Erfan Nur   +9 more
wiley   +1 more source

Effect of hydroxyurea on G gamma chain fetal hemoglobin synthesis by sickle-cell disease patients

Brazilian Journal of Medical and Biological Research, 2003
Hydroxyurea is used for sickle-cell disease patients in order to increase fetal hemoglobin synthesis and consequently decrease the severity of pain episodes.
S.M. Teixeira, L.C. Cortellazzi, H.Z.W. Grotto   +2 more
doaj   +1 more source

Topical Hydroxyurea and Psoriasis

Journal of Investigative Dermatology, 1972
Hydroxyurea, as a 10% cream, produces a significant involutionary effect on psoriatic plaques when used under continuous plastic film occlusion. When used with only partial occlusion, however, the effect is only slightly better than that of the base alone.
Zackheim, Herschel S., Karasek, Marvin A., Cox, Alvin J.   +2 more
openaire   +2 more sources

TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, randomised controlled trial

The Lancet, 2015
Background For children with sickle cell anaemia and elevated transcranial Doppler (TCD) flow velocities, regular blood transfusions effectively prevent primary stroke, but must be continued indefinitely.
R. Ware, B. Davis, W. Schultz, R., Clark Brown, B. Aygun, S. Sarnaik, I. Odame, Beng R. Fuh, A. George, William C Owen, L. Luchtman-Jones, Z. Rogers, L. Hilliard, Cynthia A. Gauger, C. Piccone, Margaret T. Lee, J. Kwiatkowski, S. Jackson, T. Scott, Miller, C. Roberts, M. Heeney, T. Kalfa, S. Nelson, Hamayun Imran, K. Nottage, Ofelia, Alvarez, Melissa M. Rhodes, A. Thompson, A. Jennifer, Rothman, K. Helton, D. Roberts, Jamie L. Coleman, M. Bonner, A. Kutlar, N. Patel, J. Wood, L. Piller, Peng Wei, Judy P Luden, N. Mortier, Susan E Stuber, N. Luban, A. Cohen, S. Pressel, R. Adams   +48 more
semanticscholar   +1 more source

Creative and Adaptive Solutions for Early Diagnosis of Sickle Cell Disease in Sub‐Saharan Africa

American Journal of Hematology, Volume 101, Issue S1, Page 17-32, April 2026.
ABSTRACT Many of the children with sickle cell disease born in sub‐Saharan Africa remain undiagnosed and untreated. Increasing capacity and infrastructure to support diagnostic and screening programs in high income countries have enabled near universal survival into adulthood.
Luke R. Smart, Catherine I. Segbefia, Isaac Odame   +2 more
wiley   +1 more source

Hydroxyurea Induced Tooth Discoloration

Turkish Journal of Hematology, 2019
WOS ...
Okuyucu, Muhammed, Atay, Memis Hilmi
openaire   +2 more sources

Giant cellulitis‐like Sweet's syndrome induced by gilteritinib

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Juan de Luque‐Fernández, Irene Rivera‐Ruiz, Irene Suárez‐Vergne, Inmaculada Sánchez‐Ramírez, Manuel Galán‐Gutiérrez, Antonio José Vélez García‐Nieto   +5 more
wiley   +1 more source

The Epidemiology of Sickle Cell Disease in Sub‐Saharan Africa: Current Knowledge and Gaps to be Filled

American Journal of Hematology, Volume 101, Issue S1, Page 5-16, April 2026.
What are the available data on incidence & prevalence prognosis risk factors of severity of sickle cell disease in sub‐Saharan Africa? ABSTRACT Sickle Cell Disease (SCD) is highly prevalent in sub‐Saharan Africa. Epidemiological data remain sparse, but regional screening and research initiatives are expanding.
Brigitte Ranque, Leon Tshilolo, Thomas N. Williams   +2 more
wiley   +1 more source

Effect of Combined Hydroxyurea and Chelation Therapy in Reducing Serum Ferritin Level, Liver and Spleen Size in Transfusion Dependent Thalassaemia Major Patients.

Journal of Rawalpindi Medical College, 2019
Background: To compare hydroxyurea plus iron chelation therapy with iron chelation therapy alone in controlling iron overload in children with beta thalassaemia major.
Tatheer Zahra, Wajeeha Amber, Itrat Fatima   +2 more
doaj  

A Pharmacist-Managed Hydroxyurea Prescribing Protocol Improves Uptake and Optimization among Patients with Sickle Cell Disease

Advances in Hematology
Sickle cell disease (SCD) is a common genetic disorder with potentially serious sequelae that can be effectively treated with hydroxyurea. Despite its favorable benefit-risk profile, hydroxyurea uptake in patients with SCD is low.
Cameron Roessner, Trudy Sale, Kelsey Uminski, Dawn Goodyear, Natalia Rydz   +4 more
doaj   +1 more source