Results 61 to 70 of about 2,125 (176)

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

Proteomic insights on root and tuber crops’ response to abiotic stress—A review

open access: yesCrop Science, Volume 65, Issue 6, November/December 2025.
Abstract Root and tuber crops are a good source of food energy on a global scale, particularly in African and Asian nations. Nevertheless, these crops can be susceptible to abiotic stresses such as excessive heat, high salinity, drought, and nutrient deficiencies, which have detrimental effects on the physiological and metabolic processes of the plants,
L. E. Siviya   +3 more
wiley   +1 more source

Health Benefits and Food Applications of Bioactive Constituents From Different Medicinal Parts (Bark, Leaf, and Fruit) of Lycium barbarum

open access: yesFood Science &Nutrition, Volume 13, Issue 10, October 2025.
The bioactive ingredients, pharmacological effects, food applications, and safety of Lycium barbarum. ABSTRACT Lycium barbarum is a plant that is a member of the Solanaceae family. Different tissues and organs from this plant are widely used in traditional Chinese medicine because of their abundant functional ingredients.
Mengfan Peng   +4 more
wiley   +1 more source

Assessment of Morphological and Tropane Alkaloids Diversity among some Henbane (Hyoscyamus niger L.) Populations

open access: yesJournal of Medicinal Plants, 2019
Background: Black henbane with the scientific name of Hyoscyamus niger which has a wide geographic distribution, is considered as one the most important species for tropane alkaloids extraction.
M Ghorbanpour   +3 more
doaj  

A modified QuEChERS method coupled with liquid chromatography-tandem mass spectrometry for the simultaneous detection and quantification of scopolamine, L-hyoscyamine, and sparteine residues in animal-derived food products

open access: yesJournal of Advanced Research, 2019
We developed a modified Quick, Easy, Cheap, Effective, Rugged, and Safe (CEN QuEChERS) extraction method coupled with liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI+/MS-MS) to identify and quantify residues of three ...
Weijia Zheng   +11 more
doaj   +1 more source

Changes of Tropane Alkaloids in Black Henbane (Hyoscyamus niger L.) in Response to Different Types of Nitrogenous Fertilizers

open access: yesJournal of Medicinal Plants, 2017
Background: Since alkaloids are nitrogenous compounds, the availability of nitrogen (N) is expected to play an important role in the biosynthesis and accumulation of alkaloids in plants.
N Banani   +2 more
doaj  

HYOSCYAMINE IN ACUTE MANIA AND LELANCHOLIA [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1883
n ...
openaire   +2 more sources

Enhancing Tropane Alkaloid Production Based on the Functional Identification of Tropine-Forming Reductase in Scopolia lurida, a Tibetan Medicinal Plant

open access: yesFrontiers in Plant Science, 2017
Scopolia lurida, a native herbal plant species in Tibet, is one of the most effective producers of tropane alkaloids. However, the tropane alkaloid biosynthesis in this plant species of interest has yet to be studied at the molecular, biochemical, and ...
Kaihui Zhao   +13 more
doaj   +1 more source

The Treatment of Mercurial Tremor by Hyoscyamine [PDF]

open access: yesThe American Journal of the Medical Sciences, 1895
n ...
openaire   +1 more source

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