Results 1 to 10 of about 23,066 (306)

Familial hyperaldosteronism [PDF]

Brazilian Journal of Medical and Biological Research, 2000
Aldosterone, the major circulating mineralocorticoid, participates in blood volume and serum potassium homeostasis. Primary aldosteronism is a disorder characterised by hypertension and hypokalaemia due to autonomous aldosterone secretion from the ...
D.J. Torpy, C.A. Stratakis, G.P. Chrousos   +2 more
doaj   +6 more sources

Different pathogenesis of glucose intolerance in two subtypes of primary aldosteronism: Aldosterone‐producing adenoma and idiopathic hyperaldosteronism

Journal of Diabetes Investigation, 2020
Aims/Introduction An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear.
Mikiko Okazaki‐Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, Hitoshi Sugihara   +5 more
doaj   +2 more sources

Hyperaldosteronism [PDF]

BMJ, 1960
G. C. Brill, B. Creamer, I. H. Mills, Jack Pullan   +3 more
openalex   +3 more sources

Hyperaldosteronism. [PDF]

BMJ, 1969
MJ Tidd
openalex   +4 more sources

Genetics of primary hyperaldosteronism. [PDF]

Endocrine-Related Cancer, 2016
Hypertension is a common medical condition and affects approximately 20% of the population in developed countries. Primary aldosteronism is the most common form of secondary hypertension and affects 8–13% of patients with hypertension. The two most common causes of primary aldosteronism are aldosterone-producing adenoma and bilateral adrenal ...
Ravi Kumar Dutta, P. Söderkvist, O. Gimm   +2 more
semanticscholar   +4 more sources

Primary hyperaldosteronism

Journal of Medical and Scientific Research, 2016
Primary aldosteronism is caused by autonomous production of aldosterone by the adrenal cortex (due to hyperplasia, adenoma, or carcinoma). It is the cause of most common secondary form of arterial hypertension.
Panduranga G, Lekkala R, Griddaluru VC, Sujatha K   +3 more
doaj   +2 more sources

Diagnosis and management of primary hyperaldosteronism in patients with hypertension: a practical approach endorsed by the British and Irish Hypertension Society

Journal of Human Hypertension, 2023
Alongside the lack of homogeneity among international guidelines and consensus documents on primary hyperaldosteronism, the National UK guidelines on hypertension do not provide extensive recommendations regarding the diagnosis and management of this ...
L. Faconti, Spoorthy Kulkarni, C. Delles, Vikas Kapil, Philip Lewis, Mark Glover, Thomas M MacDonald, Ian B. Wilkinson   +7 more
semanticscholar   +1 more source

Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

Journal of Medicinal Chemistry, 2021
The purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone synthase (hCYP11B2) inhibitor, [18F]AldoView, and to assess its potential for the detection of aldosterone-producing adenomas (APAs) with positron emission ...
K. Sander, Thibault Gendron, Klaudia A. Cybulska, Fatih Sirindil, Junhua Zhou, T. Kalber, M. Lythgoe, T. Kurzawinski, Morris J. Brown, B. Williams, E. Årstad   +10 more
semanticscholar   +1 more source

The Th17/Treg imbalance in patients with primary hyperaldosteronism and resistant hypertension.

Polish Archives of Internal Medicine, 2021
INTRODUCTION Inflammation plays a pivotal role in blood pressure regulation. Data on experimental models of hypertension and hypertensive patients reflect the imbalance between T regulatory (Treg) and Th17 effector cells (Th17).
A. Imiela, T. Mikołajczyk, M. Siedlinski, P. Dobrowolski, A. Konior-Rozlachowska, A. Wróbel, Edyta Biernat‐Kałuża, M. Januszewicz, B. Guzik, T. Guzik, A. Januszewicz, A. Prejbisz   +11 more
semanticscholar   +1 more source

Urinary sodium/potassium ratio as a screening tool for hyperaldosteronism in men with hypertension

Hypertension Research, 2021
Among individuals with hypertension, the prevalence of secondary hypertension has been reported to be ≈10%. More than half of individuals with secondary hypertension have associated hyperaldosteronism.
Hiroyoshi Segawa, A. Higashi, I. Masuda, Kengo Yoshii, T. Iwahori, H. Ueshima   +5 more
semanticscholar   +1 more source