Results 11 to 20 of about 9,929 (176)
Familial hyperaldosteronism [PDF]
Aldosterone, the major circulating mineralocorticoid, participates in blood volume and serum potassium homeostasis. Primary aldosteronism is a disorder characterised by hypertension and hypokalaemia due to autonomous aldosterone secretion from the ...
D.J. Torpy +2 more
doaj +7 more sources
Hyperaldosteronism in Mice Lacking the Distal Polybasic Tract of the γ-Subunit of the Epithelial Sodium Channel During Sodium Restriction. [PDF]
ABSTRACT Aims The epithelial sodium channel ENaC consists of the subunits α, β, and γ and is activated at an individual channel level by proteolytic processing. Murine γENaC contains a distal polybasic tract 186RKRK mediating proteolytic ENaC activation by serine proteases in vitro.
Essigke D +8 more
europepmc +2 more sources
Adrenal Venous Sampling for Subtype Diagnosis of Primary Hyperaldosteronism [PDF]
Adrenal venous sampling (AVS) is the key procedure for lateralization of primary hyperaldosteronism (PA) before surgery. Identification of the adrenal veins using computed tomography (CT) and intraoperative cortisol assay facilitates the success of ...
Mitsuhide Naruse +11 more
doaj +1 more source
Primary hyperaldosteronism [PDF]
Primary hyperaldosteronism is an important cause of hypertension. Its true prevalence is still a matter of debate, since about 10% of hypertensives may have underlying hyperaldosteronism. Primary hyperaldosteronism is due to aldosterone-secreting tumours, bilateral adrenal hyperplasia or, rarely, adrenal carcinoma or genetic causes ...
Sunil, Nadar +2 more
openaire +5 more sources
CHARACTERISTICS AND FEATURES OF CLINICAL MANIFESTATIONS OF PRIMARY HYPERALDOSTERONISM (LITERATURE REVIEW) [PDF]
Introduction. Primary hyperaldosteronism as a cause of secondary arterial hypertension ranges from 4.6 to 13.0%, and among patients with refractory hypertension to medication therapy is about 20%.
Viktor O. Shidlovskyi +8 more
doaj +1 more source
DIAGNOSIS OF ALDOSTEROMA. CLINICAL CASE
A clinical case of hyperaldosteronism identifed during hospitalization in the endocrinology department of the Healthcare Institution «Grodno University Clinic» is presented.
Nikonova L. V. +3 more
doaj +1 more source
Introduction: Patients with history of abdominal aortic aneurysm (AAA) undergoing surgical repair can have a myriad of surgical complications including compromise to large arteries branching from the aorta.
Konnor Davis +2 more
doaj +1 more source
Aldosterone is produced in the adrenal cortex and governs volume and electrolyte homeostasis. Hyperaldosteronism can occur either as primary aldosteronism (renin-independent) or secondary aldosteronism (renin-dependent). As the commonest cause of secondary hypertension, primary aldosteronism is associated with increased cardiovascular risk.
Troy H Puar, Meifen Zhang
openaire +3 more sources
Primary idiopathic hyperaldosteronism in clinical practice
Primary hyperaldosteronism (PHA) is a clinical syndrome that develops as a result of excess production of aldosterone by adrenal glomerular zone, where aldosterone secretion is completely or partially autonomous in relation to the renin-angiotensin ...
doaj +1 more source
Paradigm shift on the role of mineralocorticoid receptor antagonists in hypertension therapy
The literature review is devoted to modern ideas about the role of hyperaldosteronism as one of the important pathophysiological links in hypertension (HTN) development.
S. R. Gilyarevsky, D. O. Ladygina
doaj +1 more source

