Results 41 to 50 of about 10,536 (174)

Screening and treatment of endocrine hypertension focusing on adrenal gland disorders: a narrative review [PDF]

Journal of Yeungnam Medical Science
Most cases of high blood pressure have no identifiable cause, termed essential hypertension; however, in approximately 15% of cases, hypertension occurs due to secondary causes. Primary aldosteronism (PA) and pheochromocytoma and paraganglioma (PPGL) are
Seung Min Chung
doaj   +1 more source

Histopathological stratification of primary aldosteronism using the CYP11B2 size ratio: first evaluation in clinical routine

Histopathology, EarlyView.
CYP11B2 immunohistochemistry identifies aldosterone‐producing nodules and enables objective subtyping using the B2 ratio (B2R), defined as the size ratio between the largest and second‐largest CYP11B2‐positive nodules. A B2R ≥8.1 indicates classical histology with a dominant lesion and high likelihood of cure, whereas B2R <8.1 reflects non‐classical ...
Adam Stenman, Tim Nilsson, Henrik Falhammar, C. Christofer Juhlin   +3 more
wiley   +1 more source

Insipidary syndrome in children and adolescents (part 3)

Лечащий Врач, 2021
The review article presents current data on water-electrolyte balance in healthy and pathological state. The diseases and conditions which occur in insipidary syndrome are described.
V. V. Smirnov, L. I. Bikbaeva
doaj  

Hipertensión arterial secundaria: ¿Cuándo sospecharla y qué hacer?

Revista Médica Hondureña, 2023
Arterial hypertension is a frequent public health problem; it can be of primary or secondary etiology. Secondary hypertension due to a cause can be treated with specific interventions.
Ramón Yefrin Maradiaga Montoya
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2719-2737, December 2026.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

A Giant 5000 g Primary Adrenocortical Carcinoma: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Adrenocortical carcinoma (ACC) is an aggressive malignancy that may present without hormonal symptoms. A 64 years old woman with abdominal pain, weight loss, and anemia had a massive adrenal tumor that required complex surgery. ACC should be considered in large abdominal masses. Complete surgical resection is essential.
Sadin Zahra, Aghajanzadeh Manouchehr, Mohammad Reza Sadin, Dadashi Arsalan, Poorsafar Mahdi, Aghzadeh Zeynab, Khyabani Mahmood, Shafaghi Afshin   +7 more
wiley   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1‐Dependent Suppression of ROMK

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT Aim Hyperkalemia is prevalent in the elderly, and underlying molecular mechanisms remain incompletely understood. We hypothesized that Klotho deficiency, a feature of aging, impairs renal potassium homeostasis and contributes to hyperkalemia. Methods Klotho heterozygous knockout (KLhet) mice, characterized by reduced Klotho levels, were used ...
Wakako Kawarazaki, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Takeshi Marumo, Toshiro Fujita   +6 more
wiley   +1 more source

Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation

Frontiers in Endocrinology, 2022
BackgroundPrimary aldosteronism (PA) is the most common cause of secondary hypertension, and patients are at an increased risk of atrial fibrillation (AF) and stroke. We assessed the prevalence of PA in patients with recent stroke.MethodsWe recruited 300
Van Nguyen, Tian Ming Tu, Marlie Jane B. Mamauag, Jovan Lai, Seyed Ehsan Saffari, Seyed Ehsan Saffari, Tar Choon Aw, Lizhen Ong, Roger S. Y. Foo, Roger S. Y. Foo, Siang Chew Chai, Shaun Fones, Meifen Zhang, Troy H. Puar   +13 more
doaj   +1 more source

A Ten Year Overview of Adrenal Vein Sampling in Croatia: Insights and Outcomes

Clinical Endocrinology, Volume 105, Issue 5, Page 533-539, November 2026.
ABSTRACT Background Adrenal vein sampling (AVS) is the gold standard for subtype differentiation in primary aldosteronism (PA), yet it remains technically demanding and resource intensive. However, data on long‐term performance, learning curves, and concordance with imaging in real‐world clinical practice are limited.
Karin Zibar Tomsic, Ana Marija Alduk, Elvira Kresic, Ivana Kraljevic, Darko Kastelan   +4 more
wiley   +1 more source

Vaporised etomidate (“space oil”) misuse: A narrative review

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background Etomidate, a well‐established intravenous induction agent valued for haemodynamic stability, has emerged as a recreational drug via e‐cigarette vaping (“space oil”), particularly in Asia, including Hong Kong, prompting regulatory controls amid rising emergency presentations.
Sui Wa Au, Yu‐Yeung Yip
wiley   +1 more source