Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley +1 more source
Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice [PDF]
Galectin-3 (Gal-3) is involved in inflammation, fibrogenesis, and cardiac remodeling. Previous evidence shows that Gal-3 interacts with aldosterone in promoting macrophage infiltration and vascular fibrosis and that Gal-3 genetic and ...
Cohen Solal, Alain +8 more
core +1 more source
ABSTRACT Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies. Historically, urinary steroid profiling has been performed using low‐throughput gas chromatography mass ...
Joshua T. Bain +4 more
wiley +1 more source
Secondary hypertension as a cause of treatment resistance
In secondary hypertension, elevated blood pressure is caused by a known and/or potentially treatable underlying disease. Although the prevalence of secondary hypertension depends on the patient population and the thoroughness of applied diagnostic ...
Isabella Sudano +2 more
doaj +1 more source
ARMC 5 Variants and Risk of Hypertension in Blacks: MH- GRID Study. [PDF]
Background We recently found that ARMC 5 variants may be associated with primary aldosteronism in blacks. We investigated a cohort from the MH - GRID (Minority Health Genomics and Translational Research Bio-Repository Database) and tested the association
Berthon, Annabel +8 more
core
A rare case of unilateral adrenal hyperplasia accompanied by hypokalaemic periodic paralysis caused by a novel dominant mutation in CACNA1S: features and prognosis after adrenalectomy [PDF]
BACKGROUND: Acute hypokalaemic paralysis is characterised by acute flaccid muscle weakness and has a complex aetiological spectrum. Herein we report, for the first time, a case of unilateral adrenal hyperplasia accompanied by hypokalaemic periodic ...
Bo Yang +4 more
core +1 more source
ABSTRACT Aims The epithelial sodium channel ENaC consists of the subunits α, β, and γ and is activated at an individual channel level by proteolytic processing. Murine γENaC contains a distal polybasic tract 186RKRK mediating proteolytic ENaC activation by serine proteases in vitro.
Daniel Essigke +8 more
wiley +1 more source
Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO +9 more
core
Sex‐specific 24‐hour minimum heart rate (MHR) stratification in patients with type 2 diabetes mellitus and essential hypertension (T2DM‐EH). Three key findings are shown from subgroup analysis: (1) In the normal MHR group (Group B), advancing age independently predicts reduced deceleration capacity (DC) in both sexes.
Pingping Wu +6 more
wiley +1 more source
Liquid Chromatography-Tandem Mass Spectrometry Outperforms Radioimmunoassay in Guiding Surgical Decisions Based on Adrenal Venous Sampling in Primary Aldosteronism [PDF]
Background Adrenal venous sampling (AVS) is essential for diagnosing unilateral aldosterone oversecretion in primary aldosteronism (PA). Traditionally, AVS relies on radioimmunoassay (RIA) to measure plasma aldosterone concentration (PAC), although RIA ...
Bo-Ching Lee +10 more
doaj +1 more source

