Results 51 to 60 of about 12,721 (210)

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Primary Hyperaldosteronism

, 2011
Practical relevance Primary hyperaldosteronism is probably the most common adrenocortical disorder in cats. As in humans, it is often unrecognised, which excludes a potentially large number of cats from appropriate treatment.
Sara Galac, Sylvia C Djajadiningrat-Laanen, Hans Kooistra   +2 more
core   +1 more source

A Case of Deoxycorticosterone-Producing Adrenocortical Carcinoma: A Review of Etiologies of Hypertension With Hypokalemia

Annals of Internal Medicine: Clinical Cases
Resistant hypertension with hypokalemia can occur in patients with secondary hypertension with a differential diagnosis that includes primary hyperaldosteronism, secondary hyperaldosteronism, and pseudohyperaldosteronism. Herein, we report a rare case of
Farid Arman, Salila Kurra, Zhe Ran Susan Duan, Eric Siddall   +3 more
doaj   +1 more source

Insipidary syndrome in children and adolescents (part 3)

Лечащий Врач, 2021
The review article presents current data on water-electrolyte balance in healthy and pathological state. The diseases and conditions which occur in insipidary syndrome are described.
V. V. Smirnov, L. I. Bikbaeva
doaj  

The problem of timely diagnosis of primary hyperaldosteronism. Clinical case

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
A clinical case is presented of delayed diagnosis of primary hyperaldosteronism (PHA) due to aldosterone-producing adenoma. Suspicion of PHA arises in case of persistent combination of hypertension with hypokalemia of various severity, a specific ...
V.M. Zhdan, H.V. Volchenko, M.Yu. Babanina, M.V. Tkachenko, O.A. Kiryan, Ye.M. Kitura, I.V. Ivanitsky   +6 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Primary hyperaldosteronism in cats: expanding the diagnostic net [PDF]

, 2014
Primary hyperaldosteronism or low-renin hyperaldosteronism in cats is characterized by inappropriately high aldosterone secretion from one or both adrenal glands, with systemic arterial hypertension and hypokalemia as leading clinical manifestations.
Geneeskunde van gezelschapsdieren, Advances in Veterinary Medicine, Djajadiningrat-Laanen, S.C.   +2 more
core   +1 more source

A Ten Year Overview of Adrenal Vein Sampling in Croatia: Insights and Outcomes

Clinical Endocrinology, EarlyView.
ABSTRACT Background Adrenal vein sampling (AVS) is the gold standard for subtype differentiation in primary aldosteronism (PA), yet it remains technically demanding and resource intensive. However, data on long‐term performance, learning curves, and concordance with imaging in real‐world clinical practice are limited.
Karin Zibar Tomsic, Ana Marija Alduk, Elvira Kresic, Ivana Kraljevic, Darko Kastelan   +4 more
wiley   +1 more source

Rhabdomyolysis as first presentation of the Conn’s syndrome: a clinical case

Arterial Hypertension
Primary hyperaldosteronism is the leading cause of secondary hypertension, often presented with hypokalemia and even rare with its consequences. We describe a case of a 62-year-old man admitted to the emergency department with rhabdomyolysis from severe ...
Irida Kecaj, Ergita Nelaj, Ilir Gjermeni, Arben Gjata, Kei Xhixhabesi, Irda Rrugeja, Ina Refatllari, Margarita Gjata   +7 more
doaj   +1 more source