Results 51 to 60 of about 15,712 (223)

Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism

Frontiers in Endocrinology, 2023
ObjectivesThe aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).Methods269 patients from the prospective German Conn Registry with PA were
Nabeel Mansour, Andreas Mittermeier, Roman Walter, Balthasar Schachtner, Jan Rudolph, Bernd Erber, Vanessa F. Schmidt, Daniel Heinrich, Denise Bruedgam, Lea Tschaidse, Hanna Nowotny, Martin Bidlingmaier, Sonja L. Kunz, Christian Adolf, Jens Ricke, Martin Reincke, Nicole Reisch, Moritz Wildgruber, Michael Ingrisch   +18 more
doaj   +1 more source

Improvement of Health‐Related Quality of Life and Mental Health After Unilateral Adrenalectomy for Primary Aldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Background Primary aldosteronism (PA) has been linked with reduced health‐related quality of life (QoL) and increased prevalence of anxiety and depression. While most studies compared patients with PA to healthy subjects, this study focused on comparison with hypertensive patients without PA to identify PA‐specific effects.
Sybille Fuld, Christian Adolf, Georgiana Constantinescu, Manuel Schulze, Denise Brüdgam, Carmina T. Fuss, Hanna Remde, Lydia Kürzinger, Sven Gruber, Jun Yang, Amy Kang, Martin Reincke, Felix Beuschlein, Graeme Eisenhofer, Jacques W. M. Lenders, Christina Pamporaki   +15 more
wiley   +1 more source

Rhabdomyolysis as first presentation of the Conn’s syndrome: a clinical case

Arterial Hypertension
Primary hyperaldosteronism is the leading cause of secondary hypertension, often presented with hypokalemia and even rare with its consequences. We describe a case of a 62-year-old man admitted to the emergency department with rhabdomyolysis from severe ...
Irida Kecaj, Ergita Nelaj, Ilir Gjermeni, Arben Gjata, Kei Xhixhabesi, Irda Rrugeja, Ina Refatllari, Margarita Gjata   +7 more
doaj   +1 more source

Screening of Hyperaldosteronism on the Investigation of Secondary Hypertension: Single-centre Experience

İstanbul Medical Journal, 2023
Introduction:Primary hyperaldosteronism (PHA), is a clinical syndrome that is defined as inappropriately increased serum aldosterone secretion and low plasma renin levels. PHA has been reported as the most common cause of secondary hypertension.
Gülsüm Bingöl, Emre Özmen, Özge Özden, Leyla Bulut Arsoy, Yusuf Emre Uzun, Muharrem Nasifov, Esra Şüheda Hatipoğlu   +6 more
doaj   +1 more source

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Quantitative value of aldosterone-renin ratio for detection of aldosterone-producing adenoma: The Aldosterone-Renin Ratio for Primary Aldosteronism (AQUARR) study [PDF]

, 2017
Background Current guidelines recommend use of the aldosterone\u2010renin ratio (ARR) for the case detection of primary aldosteronism followed by confirmatory tests to exclude false\u2010positive results from further diagnostic workup.
Andronico, Giuseppe, Armanini, Decio, Belfiore, Anna, Bernini, Giampaolo, Bisogni, Valeria, Boscaro, Marco, Caliumi, Chiara, Cesari, Maurizio, Desideri, Giovambattista, Fabris, Bruno, Ferri, Claudio, Ganzaroli, Chiara, Ghigo, Ezio, Giacchetti, Gilberta, Letizia, Claudio, Maccario, Mauro, Maiolino, Giuseppe, Mallamaci, Francesca, Mannelli, Massimo, Mantero, Franco, Mattarello, Mee Yung, Moretti, Angelica, Opocher, Giuseppe, Palumbo, Gaetana, Parenti, Gabriele, Pessina, Achille Cesare, Plebani, Mario, Porteri, Enzo, Rizzoni, Damiano, Ronconi, Vanessa, Rossi, Ermanno, Rossi, Gian Paolo, Rossitto, Giacomo, Seccia, Teresa Maria, Semplicini, Andrea, Zoccali, Carmine   +35 more
core   +3 more sources

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Primary Hyperaldosteronism: When to Suspect It and How to Confirm Its Diagnosis

Endocrines, 2022
The definition of primary hyperaldosteronism (PA) has shifted, as progress has been made in understanding the disease. PA can be produced by unilateral or bilateral cortical adrenal hyperproduction of aldosterone, due to hyperplasia, aldosterone ...
Jorge Gabriel Ruiz-Sánchez, Mario Pazos Guerra, Diego Meneses, Isabelle Runkle   +3 more
doaj   +1 more source

Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler, Klara R. Klein, Ildiko Lingvay, Anthony Pick, Liana K. Billings   +4 more
wiley   +1 more source

Primary hyperaldosteronism among Chinese hypertensive patients: how are we doing in a local district in Hong Kong [PDF]

, 2012
OBJECTIVES: To estimate the point prevalence of primary hyperaldosteronism in a government out-patient setting and to compare associated patient characteristics with those having essential hypertension.
Fu, SN, Fung, LM, Luk, W, Sy, WM, Wong, CKH   +4 more
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