Results 51 to 60 of about 17,749 (253)

Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism

Frontiers in Endocrinology, 2023
ObjectivesThe aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).Methods269 patients from the prospective German Conn Registry with PA were
Nabeel Mansour, Andreas Mittermeier, Roman Walter, Balthasar Schachtner, Jan Rudolph, Bernd Erber, Vanessa F. Schmidt, Daniel Heinrich, Denise Bruedgam, Lea Tschaidse, Hanna Nowotny, Martin Bidlingmaier, Sonja L. Kunz, Christian Adolf, Jens Ricke, Martin Reincke, Nicole Reisch, Moritz Wildgruber, Michael Ingrisch   +18 more
doaj   +1 more source

Emerging methods for subtype differentiation in primary aldosteronism

Journal of Internal Medicine, Volume 299, Issue 2, Page 178-195, February 2026.
Abstract Primary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two‐ to fourfold greater risk of cardiovascular disease, renal failure, and death. PA is caused by increased secretion of aldosterone from one adrenal gland in 30% of the patients and both adrenal ...
Oskar Ragnarsson, C. Christofer Juhlin, Tobias Åkerström, Per Dahlqvist, Henrik Falhammar, Per Hellman   +5 more
wiley   +1 more source

Adrenal Vein Sampling in Primary Aldosteronism: A Pictorial Essay for Optimal Left-Side Sampling

Journal of the Korean Society of Radiology, 2023
Primary aldosteronism (PA) is a curable cause of hypertension. Recent studies have revealed that the actual prevalence of PA is higher than previously recognized.
Gi Joo Kim, Myung Sub Kim, Hyun Pyo Hong, Young Rae Lee, Yeon Gyu Choi   +4 more
doaj   +1 more source

Mass Spectrometric Measurements of 11‐Deoxycortisol, Androstenedione and Dehydroepiandrosterone Are Superior to Cortisol to Assess Selectivity of Non‐Stimulated Adrenal Vein Sampling

Clinical Endocrinology, Volume 104, Issue 1, Page 10-18, January 2026.
ABSTRACT Objective Successful adrenal venous sampling (AVS) is traditionally assessed using the ratio of cortisol in adrenal to peripheral venous plasma to calculate the selectivity index. With mass spectrometry other steroids can be simultaneously measured that may improve numbers of apparent successful sampling procedures.
Francesco Alessi, Christina Pamporaki, Mirko Peitzsch, Georgiana Constantinescu, Hanna Remde, Lydia Kürzinger, Carmina T. Fuss, Manuel Schulze, Sybille Fuld, Sradha Kotwal, Jun Yang, Martin Reincke, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +14 more
wiley   +1 more source

Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]

, 2015
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO, FIACCO, FEDERICA, LETIZIA, Claudio, MARINELLI, CRISTIANO, MITTERHOFER, Anna Paola, PETRAMALA, LUIGI, TINTI, FRANCESCA, UMBRO, ILARIA, ZAVATTO, ASSUNTA, ZINGARETTI, VIVIANA   +9 more
core  

Rhabdomyolysis as first presentation of the Conn’s syndrome: a clinical case

Arterial Hypertension
Primary hyperaldosteronism is the leading cause of secondary hypertension, often presented with hypokalemia and even rare with its consequences. We describe a case of a 62-year-old man admitted to the emergency department with rhabdomyolysis from severe ...
Irida Kecaj, Ergita Nelaj, Ilir Gjermeni, Arben Gjata, Kei Xhixhabesi, Irda Rrugeja, Ina Refatllari, Margarita Gjata   +7 more
doaj   +1 more source

Eplerenone improves kidney function and cardiac performance in obese male mice

Diabetic Medicine, Volume 43, Issue 1, January 2026.
Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Ayman K. Banah, Bingxue Qi, Ryan Koh, Alexander Lawlor, Tianzhen Wang, Vishal Musale, Joanne Mains, Colin E. Murdoch, Li Kang   +8 more
wiley   +1 more source

Primary hyperaldosteronism among Chinese hypertensive patients: how are we doing in a local district in Hong Kong [PDF]

, 2012
OBJECTIVES: To estimate the point prevalence of primary hyperaldosteronism in a government out-patient setting and to compare associated patient characteristics with those having essential hypertension.
Fu, SN, Fung, LM, Luk, W, Sy, WM, Wong, CKH   +4 more
core  

Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms [PDF]

, 2014
β-Arrestin (βarr)-1 and β-arrestin-2 (βarrs) are universal G-protein-coupled receptor adapter proteins that negatively regulate cardiac β-adrenergic receptor (βAR) function via βAR desensitization and downregulation.
Bathgate Siryk, Ashley, Cannavo, Alessandro, Dabul, Samalia, DE LUCIA, CLAUDIO, Gao, Erhe, Koch, Walter J, LEOSCO, DARIO, Liccardo, Daniela, Lymperopoulos, Anastasios, Pandya, Krunal, RENGO, GIUSEPPE, Walklett, Karlee   +11 more
core   +1 more source

Primary Hyperaldosteronism: When to Suspect It and How to Confirm Its Diagnosis

Endocrines, 2022
The definition of primary hyperaldosteronism (PA) has shifted, as progress has been made in understanding the disease. PA can be produced by unilateral or bilateral cortical adrenal hyperproduction of aldosterone, due to hyperplasia, aldosterone ...
Jorge Gabriel Ruiz-Sánchez, Mario Pazos Guerra, Diego Meneses, Isabelle Runkle   +3 more
doaj   +1 more source