Results 51 to 60 of about 17,817 (253)

Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism

open access: yesFrontiers in Endocrinology, 2023
ObjectivesThe aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).Methods269 patients from the prospective German Conn Registry with PA were
Nabeel Mansour   +18 more
doaj   +1 more source

Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]

open access: yes, 2015
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO   +9 more
core  

Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice [PDF]

open access: yes, 2016
Galectin-3 (Gal-3) is involved in inflammation, fibrogenesis, and cardiac remodeling. Previous evidence shows that Gal-3 interacts with aldosterone in promoting macrophage infiltration and vascular fibrosis and that Gal-3 genetic and ...
Cohen Solal, Alain   +8 more
core   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Adrenal Vein Sampling in Primary Aldosteronism: A Pictorial Essay for Optimal Left-Side Sampling

open access: yesJournal of the Korean Society of Radiology, 2023
Primary aldosteronism (PA) is a curable cause of hypertension. Recent studies have revealed that the actual prevalence of PA is higher than previously recognized.
Gi Joo Kim   +4 more
doaj   +1 more source

Quantitative value of aldosterone-renin ratio for detection of aldosterone-producing adenoma: The Aldosterone-Renin Ratio for Primary Aldosteronism (AQUARR) study [PDF]

open access: yes, 2017
Background Current guidelines recommend use of the aldosterone\u2010renin ratio (ARR) for the case detection of primary aldosteronism followed by confirmatory tests to exclude false\u2010positive results from further diagnostic workup.
Andronico, Giuseppe   +35 more
core   +3 more sources

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

open access: yesExperimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó   +1 more
wiley   +1 more source

Rhabdomyolysis as first presentation of the Conn’s syndrome: a clinical case

open access: yesArterial Hypertension
Primary hyperaldosteronism is the leading cause of secondary hypertension, often presented with hypokalemia and even rare with its consequences. We describe a case of a 62-year-old man admitted to the emergency department with rhabdomyolysis from severe ...
Irida Kecaj   +7 more
doaj   +1 more source

Primary hyperaldosteronism among Chinese hypertensive patients: how are we doing in a local district in Hong Kong [PDF]

open access: yes, 2012
OBJECTIVES: To estimate the point prevalence of primary hyperaldosteronism in a government out-patient setting and to compare associated patient characteristics with those having essential hypertension.
Fu, SN   +4 more
core  

Hypertension - state of the art 2017 [PDF]

open access: yes, 2017
No abstract ...
McCallum, Linsay
core   +1 more source

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