Results 61 to 70 of about 23,066 (306)

Sodium chloride versus glucose solute as a volume replacement therapy for more effective decongestion in acute heart failure (SOLVRED‐AHF): A prospective, randomized, mechanistic study

open access: yesEuropean Journal of Heart Failure, EarlyView.
The impact of sodium chloride (NaCl) supplementation on proximal and distal tubular reabsorption in acute heart failure (AHF). Abstract Aims We questioned the long‐standing paradigm that sodium/chloride restriction is essential for effective decongestion in acute heart failure (AHF). This study compared the decongestive effects of two isotonic infusion
Jan Biegus   +7 more
wiley   +1 more source

Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice [PDF]

open access: yes, 2016
Galectin-3 (Gal-3) is involved in inflammation, fibrogenesis, and cardiac remodeling. Previous evidence shows that Gal-3 interacts with aldosterone in promoting macrophage infiltration and vascular fibrosis and that Gal-3 genetic and ...
Cohen Solal, Alain   +8 more
core   +1 more source

A Case of Deoxycorticosterone-Producing Adrenocortical Carcinoma: A Review of Etiologies of Hypertension With Hypokalemia

open access: yesAnnals of Internal Medicine: Clinical Cases
Resistant hypertension with hypokalemia can occur in patients with secondary hypertension with a differential diagnosis that includes primary hyperaldosteronism, secondary hyperaldosteronism, and pseudohyperaldosteronism. Herein, we report a rare case of
Farid Arman   +3 more
doaj   +1 more source

PTH Modulation by Aldosterone and Angiotensin II is Blunted in Hyperaldosteronism and Rescued by Adrenalectomy.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2019
CONTEXT Accumulating evidences suggest a link between adrenocortical zona glomerulosa and parathyroid gland through mechanisms that remain unexplored.
L. Lenzini   +8 more
semanticscholar   +1 more source

An Update on Familial Hyperaldosteronism [PDF]

open access: yesHormone and Metabolic Research, 2015
AbstractFamilial forms of primary aldosteronism have been suggested to account for up to 6% of cases in referral centers. For many years, the genetics of familial hyperaldosteronism remained unknown, with the notable exception of glucocorticoid-remediable aldosteronism, due to unequal crossing
Ute I. Scholl, H. E. Korah
openaire   +3 more sources

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

open access: yes, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S.   +7 more
core  

Hypertension - state of the art 2017 [PDF]

open access: yes, 2017
No abstract ...
McCallum, Linsay
core   +1 more source

Adrenal Vein Sampling: Radiation Dose Reduction on New Angiography Platform

open access: yesThe Arab Journal of Interventional Radiology, 2020
Objectives: Primary aldosteronism is one of the most common causes of secondary hypertension. Distinguishing unilateral from bilateral disease is essential as those with unilateral adrenal disease will benefit from adrenalectomy. This is best achieved by
Ali Alsafi   +6 more
doaj   +1 more source

Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background Data on the effects of excess aldosterone on glucose metabolism are inconsistent. This study compared the changes in glucose metabolism in patients with primary aldosteronism (PA) after adrenalectomy or treatment with a mineralocorticoid ...
Yu-Fang Lin   +6 more
doaj   +1 more source

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