Results 11 to 20 of about 34,447 (277)
Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS. [PDF]
FASEB JIn a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Weng Y +12 more
europepmc +2 more sources
Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities [PDF]
, 2021 PCOS is one of the most common endocrine diseases affecting women of reproductive age. Its etiology remains unresolved but it is thought to have a genetic basis as well as interactions with other environmental factors.
Ghazeeri, G. +5 more
core +1 more source
Scientific Reports, 2023 Polycystic ovary syndrome (PCOS) is a highly complex reproductive metabolic disorder and women with PCOS have high prevalence of non-alcoholic fatty liver disease (NAFLD).
So-hyeon Hong +7 more
semanticscholar +1 more source
Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women—What Is the Evidence?
Journal of Clinical Endocrinology and Metabolism, 2023 Hyperandrogenism in women, such as polycystic ovary syndrome, ovarian hyperthecosis, congenital adrenal hyperplasia, and androgen-secreting tumors, are all associated with increased prevalence of cardiovascular risk factors that include type 2 diabetes ...
A. Hirschberg
semanticscholar +1 more source
N6-methyladenosine demethylase FTO related to hyperandrogenism in PCOS via AKT pathway
Gynecological Endocrinology, 2023 Background Polycystic ovary syndrome (PCOS) was known as the common endocrine disease in women, featured as hyperandrogenism, ovulation disorders, etc.
Yuanxue Jing +6 more
semanticscholar +1 more source
Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman
Journal of Clinical Endocrinology and Metabolism, 2022 Postmenopausal hyperandrogenism is a condition caused by relative or absolute androgen excess originating from the ovaries and/or the adrenal glands. Hirsutism, in other words, increased terminal hair growth in androgen-dependent areas of the body, is ...
A. Hirschberg
semanticscholar +1 more source
Hyperandrogenism in Women with Polycystic Ovarian Syndrome: Pathophysiology and Controversies
Androgens: Clinical Research and Therapeutics, 2022 Polycystic ovary syndrome (PCOS) is an essential differential diagnosis of hyperandrogenism to consider in women, with most women presenting with irregular menses, infertility, and hirsutism.
Sarah A. Kanbour, A. Dobs
semanticscholar +1 more source
Frontiers in Nutrition, 2022 Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease that is characterized by oligo-ovulation or anovulation, hyperandrogenism, and polycystic ovaries observed using ultrasound with high clinical heterogeneity.
Wenqian Li +6 more
doaj +1 more source
Gestational Hyperandrogenism in Developmental Programming
Endocrinology, 2017 Vasantha Padmanabhan, Arpita Vyas
exaly +2 more sources
مجلة الكوفة الطبية, 2023 Background: The diagnosis of polycystic ovarian syndrome (PCOS) in adolescent girls can be difficult because symptoms are shared with normal pubertal development.
Shymaa Khazaal Abid Jabok +1 more
doaj +1 more source