Results 61 to 70 of about 34,447 (277)

Systematic analysis of the biological roles and pharmacological properties of D-chiro-inositol [PDF]

Гинекология, 2020
D-chiroinositol (DCI) is one of the 9 inositol isomers that forms inositol phosphoglycans, which are mediators of the action of insulin. The metabolism of DCI and myo-inositol (MI) is impaired against the background of insulin resistance, including the ...
Olga A. Gromova, Ivan Yu. Torshin, Elena V. Uvarova, Natalya I. Tapilskaya, Alla G. Kalacheva   +4 more
doaj   +1 more source

Hyperandrogenism and skin: polycystic ovary syndrome and peripheral insulin resistance [PDF]

, 2005
The polycystic ovary syndrome is an extremely common endocrine disorder in women of chilbearing age. It is characterized by menstrual disturbance, hyperandrogenism and/or hyperandrogenemia.
Bagatin, Edileia, Hassun, Karime Marques, Parada, Meire Odete Américo Brasil, Talarico Filho, Sergio, Yarak, Samira   +4 more
core   +4 more sources

Hyperandrogenic States in Pregnancy

Physiological Research, 2011
Hyperandrogenic states in pregnancy are almost always the result of a condition that arises during pregnancy. The onset of virilization symptoms is often very fast. The mother is protected against hyperandrogenism by a high level of SHBG, by placental aromatase and a high level of progesterone.
N, Kaňová, M, Bičíková
openaire   +2 more sources

Inflammation triggered by saturated fat ingestion is linked to insulin resistance and hyperandrogenism in PCOS.

Journal of Clinical Endocrinology and Metabolism, 2020
CONTEXT Inflammation and insulin resistance are often present in Polycystic Ovary Syndrome (PCOS). OBJECTIVE We determined the effect of saturated fat ingestion on mononuclear cell (MNC) nuclear factor-κB (NFκB) activation, NFκB, inhibitory-κBα (IκBα ...
F. González, R. Considine, O. Abdelhadi, A. Acton   +3 more
semanticscholar   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Clinical application of method diagnostics hyperandrogenism syndrome on women of reproductive age

RUDN Journal of Medicine, 2010
Hyperandrogenism is one of the pathology of endocrin system, which is more difficult diagnosed at reproductive age of women. There is caeful history and assessment clinical presentation which dominate in diagnostics of hyperandrogenism in the ...
N I Volkova, A N Rymashevsky, T A Dimitriadi   +2 more
doaj  

Associations between anxiety, body mass index, and sex hormones in women [PDF]

, 2019
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.
Bae, Y., Ceglarek, U., Engel, C., Enzenbach, C., Glaesmer, H., Hinz, A., Kratzsch, J., Luck, T., Pabst, A., Riedel-Heller, S., Sacher, J., Stanik, J., Stanikova, D., Thiery, J., Wirkner, K.   +14 more
core   +2 more sources

Hyperandrogenism and insulin resistance‐induced fetal loss: evidence for placental mitochondrial abnormalities and elevated reactive oxygen species production in pregnant rats that mimic the clinical features of polycystic ovary syndrome

Journal of Physiology, 2019
Women with polycystic ovary syndrome (PCOS) commonly suffer from miscarriage, but the underlying mechanisms remain unknown. Herein, pregnant rats chronically treated with 5α‐dihydrotestosterone (DHT) and insulin exhibited hyperandrogenism and insulin ...
Yuehui Zhang, Wei Zhao, Hongfei Xu, Min Hu, Xiaozhu Guo, Wenyan Jia, Guoqi Liu, Juan Li, P. Cui, S. Lager, A. Sferruzzi-Perri, Wei Li, Xiao-Ke Wu, Yanhua Han, M. Brännström, Linus R. Shao, H. Billig   +16 more
semanticscholar   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Population and Diagnostic Characteristics of Polycystic Ovary Syndrome and Hyperandrogenism

Women's Health Reports
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder frequently characterized by hyperandrogenism that presents acute and chronic health risks. International guidelines for the assessment of PCOS endorse Rotterdam criteria for diagnosis,
Crystal Clark Douglas, Juan Ulises Rojo
doaj   +1 more source