Risk factors for sensorineural hearing loss among high-risk infants in Golestan province, Iran in 2010 - 2011 [PDF]
Background: Hearing impairment, as one of the most common birth defects, is a hidden disability with negative impacts on speech and cognitive development. Objectives: The aim of this study was to assess the prevalence of sensorineural hearing loss (SNHL)
Alaee, E.+3 more
core +2 more sources
Neonatal morbidities and developmental delay in moderately preterm-born children [PDF]
BACKGROUND AND OBJECTIVE: Children born moderately preterm (32-35(6/7) weeks' gestation) are at increased risk of both neonatal morbidities and developmental delays in early childhood.
Bocca-Tjeertes, I.F.+4 more
core +2 more sources
MIF-mediated hemodilution promotes pathogenic anemia in experimental African trypanosomosis [PDF]
Animal African trypanosomosis is a major threat to the economic development and human health in sub-Saharan Africa. Trypanosoma congolense infections represent the major constraint in livestock production, with anemia as the major pathogenic lethal ...
Beschin, Alain+17 more
core +5 more sources
Hyperbilirubinemia is a problem that often occurs in newborns. The cause of hyperbilirubinemia is multifactorial including maternal, perinatal or environmental factors that can be risk factors in newborns.
Elsa Anna Pratiwi+2 more
doaj +1 more source
Brainstem auditory evoked responses in an equine patient population. Part II: foals. [PDF]
BackgroundReports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited.Hypothesis/objectivesTo describe BAER findings and associated causes of hearing loss in foals.AnimalsStudy group 18 foals (15 ...
Aleman, M+3 more
core +1 more source
Severe neonatal hyperbilirubinemia induces temporal and occipital lobe seizures. [PDF]
To examine the origin of seizures induced by severe neonatal hyperbilirubinemia, The EEG characteristics of seizures were analyzed in newborns with and without severe neonatal hyperbilirubinemia. Fisher's exact test was used to determine the specificity.
Lian Zhang
doaj +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source
Extracorporeal membrane oxygenation with multiple-organ failure: Can molecular adsorbent recirculating system therapy improve survival? [PDF]
BACKGROUND: Liver dialysis, molecular adsorbent recirculating system (MARS) particularly, has been used in liver failure to bridge to transplantation.
Cavarocchi, Nicholas C.+2 more
core +2 more sources
Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions
Hyperbilirubinemia is a pathological condition, very often indicative of underlying liver condition that is characterized by excessive accumulation of conjugated or unconjugated bilirubin in sinusoidal blood.
Eleni Kotsampasakou+2 more
doaj +1 more source
Hereditary hyperbilirubinemias
Inherited disorders of bilirubin metabolism involve four autosomal recessive syndromes: Gilbert, Crigler- Najjar, Dubin-Johnson and Rotor, among which the first two are characterized by unconjugated and the second two by conjugated hyperbilirubinemia. Gilbert syndrome occurs in 2%-10% of general population, while others are rare. Except for
openaire +3 more sources