Results 41 to 50 of about 59,923 (283)

Severe neonatal hyperbilirubinemia induces temporal and occipital lobe seizures. [PDF]

PLoS ONE, 2018
To examine the origin of seizures induced by severe neonatal hyperbilirubinemia, The EEG characteristics of seizures were analyzed in newborns with and without severe neonatal hyperbilirubinemia. Fisher's exact test was used to determine the specificity.
Lian Zhang
doaj   +1 more source

Investigation of Risk Factors Related to the Development of Hepatic Dysfunction in Patients with a Low and Moderate Cardiac Risk During Open-Heart Surgeries [PDF]

Brazilian Journal of Cardiovascular Surgery, 2020
Objective: To determine the possible risk factors associated with hepatic dysfunction during open-heart surgeries. Methods: After excluding 71 patients, 307 patients with possible low and moderate cardiac risk who underwent either coronary artery bypass
Ayse Baysal, Gonul Sagiroglu, Mevlut Dogukan, Ismail Ozkaynak   +3 more
doaj   +1 more source

Risk factors analysis of hyperbilirubinemia after off-pump coronary artery bypass grafting: a retrospective observational study

Journal of Cardiothoracic Surgery, 2021
Background Hyperbilirubinemia is a common complication after off-pump coronary artery bypass grafting (OPCAB), but the incidence and the risk factors are unclear.
Yingdi Gao, Dongjie Li, Honghong Dong, Yulin Guo, Yuanshu Peng, Yan Liu, Pixiong Su   +6 more
doaj   +1 more source

Curated human hyperbilirubinemia data and the respective OATP1B1 and 1B3 inhibition predictions

Data in Brief, 2017
Hyperbilirubinemia is a pathological condition, very often indicative of underlying liver condition that is characterized by excessive accumulation of conjugated or unconjugated bilirubin in sinusoidal blood.
Eleni Kotsampasakou, Sylvia E. Escher, Gerhard F. Ecker   +2 more
doaj   +1 more source

Hereditary hyperbilirubinemias

Srpski arhiv za celokupno lekarstvo, 2014
Inherited disorders of bilirubin metabolism involve four autosomal recessive syndromes: Gilbert, Crigler- Najjar, Dubin-Johnson and Rotor, among which the first two are characterized by unconjugated and the second two by conjugated hyperbilirubinemia. Gilbert syndrome occurs in 2%-10% of general population, while others are rare. Except for
openaire   +3 more sources

SIGNIFICANT FACTORS INFLUENCING HYPERBILIRUBINEMIA AT SANTO YUSUF MOTHER AND CHILD HOSPITAL, NORTH JAKARTA USING BINARY LOGISTIC REGRESSION

Barekeng
Hyperbilirubinemia is a problem that often occurs in newborns. The cause of hyperbilirubinemia is multifactorial including maternal, perinatal or environmental factors that can be risk factors in newborns.
Elsa Anna Pratiwi, Nunung Nurhayati, Idha Sihwaningrum   +2 more
doaj   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Sappanwood extract modulates hepatic structure–function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia

Animal Models and Experimental Medicine, EarlyView.
Phenylhydrazine (PHZ) induces hemolytic anemia characterized by increased erythrocyte destruction and ineffective erythropoiesis, leading to hepcidin suppression through disruption of the BMP/SMAD signaling pathway. Reduced hepcidin levels enhance intestinal iron absorption and hepatic iron accumulation, leading to hepatic iron overload.
Mohammad Indra Pratama, Ratu Safitri, Desak Made Malini, Mas Rizky A. A. Syamsunarno, Mohammad Ghozali, Madihah Madihah   +5 more
wiley   +1 more source

Validation of transcutaneous bilirubin nomogram for identifying neonatal hyperbilirubinemia in healthy Chinese term and late-preterm infants: a multicenter study

Jornal de Pediatria, 2014
OBJECTIVE: to prospectively validate a previously constructed transcutaneous bilirubin (TcB) nomogram for identifying severe hyperbilirubinemia in healthy Chinese term and late-preterm infants.
Zhangbin Yu, Shuping Han, Jinxia Wu, Mingxia Li, Huaiyan Wang, Jimei Wang, Jiebo Liu, Xinnian Pan, Jie Yang, Chao Chen   +9 more
doaj   +3 more sources

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source