Results 51 to 60 of about 51,743 (231)

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Effective second-line treatment with cetuximab and bevacizumab in a patient with hepatic metastases of colorectal cancer and hyperbilirubinemia [PDF]

, 2007
Background: Irinotecan-based second-line chemotherapy of metastatic colorectal cancer (CRC) is effective, it might, however, be contraindicated in cases of severe liver dysfunction due to advanced liver metastases.
Heinemann, Volker, Laessig, Dorit, Michaely, Henrik Jakob, Moosmann, Nicolas, Schulz, Christoph   +4 more
core   +1 more source

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, EarlyView.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source

Etiologies of Prolonged Unconjugated Hyperbilirubinemia in Neonates Admitted to Neonatal Wards [PDF]

Iranian Journal of Neonatology, 2015
Background: Jaundice is a common condition among neonates. Prolonged unconjugated hyperbilirubinemia occurs when jaundice persists beyond two weeks in term neonates and three weeks in preterm neonates.
Mohammad Kazem Sabzehei, Behnaz Basiri, Zahra Gohari, Hassan Bazmamoun   +3 more
doaj  

Correlation between Prolonged Hyperbilirubinemia and Serum Zinc Level in Term Neonates [PDF]

Iranian Journal of Neonatology, 2019
Background: Prolonged hyperbilirubinemia is defined as jaundice persisting more than two and three weeks of life in term and preterm neonates, respectively. In total, 15-40% of jaundiced neonates became prolonged.
Mousa Ahmadpour-kacho, Yadollah Zahedpasha, Soryia Khafri, Sajedeh Omidbakhsh-Amiri, Sadra Tehrani   +4 more
doaj   +1 more source

The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]

, 2011
Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core  

Evidence for the benefit of prenatal pelvimetry in breech presentation at term: A low intertuberous distance is associated with assisted head delivery and short‐term neonatal morbidity

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Guidelines on vaginal breech delivery have several restrictions concerning feto‐maternal parameters. To date, they neglect the impact of prenatal pelvimetry, especially of the intertuberous distance (ITD), in nulliparous women attempting vaginal breech birth.
Julia Schmidt, Anna Elisabeth Hentrich, Anne Kristina Kämpf, Eileen Deuster, Samira Catharina Hoock, Frank Louwen, Lukas Jennewein   +6 more
wiley   +1 more source

Enasidenib in the treatment of relapsed/refractory acute myeloid leukemia: an evidence-based review of its place in therapy. [PDF]

, 2019
Introduction: Acute myeloid leukemia (AML) remains a disease with high mortality, especially for older patients and those with relapsed/refractory (R/R) disease.
Galkin, Maria, Jonas, Brian A
core   +1 more source

Management of neonatal hyperbilirubinemia: Pediatricians' practices and educational needs [PDF]

, 2006
Background Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention of bilirubin-induced encephalopathy. In this study, we evaluated the New Jersey pediatricians' practices and beliefs regarding the management of ...
Anna Petrova, Rajeev Mehta, Gillian Birchwood, Barbara Ostfeld, Thomas Hegyi, AAP Subcommittee on Neonatal Hyperbilirubinemia, American Academy of Pediatrics Subcommittee on Hyperbilirubinemia, G Bertini, TB Newman, LM Gartner, Christakis, LR Atkinson, LR Frankel, American Academy of Pediatrics. Provisional Committee for Quality Improvement and Subcommittee on Hyperbilirubinemia, JR Britton, UR Kotagal, MD Cabana, AK Brown, L Johnson, T Valaes, TW Hansen, VA Moyer, FF Rubaltelli, VK Bhutani, WD Engle, MJ Maisels, S Nanjundaswamy, LA Stokowski, TB Newman, DS Seidman, AP Schneider 2nd, LM Gartner, TB Newman, VK Bhutani, A Cartwright, HG Gough, P Edwards   +36 more
core   +1 more source

Diagnostic dilemma of cystic biliary atresia: A series of two cases and brief review of the diagnostic modalities

JPGN Reports, EarlyView.
Abstract Cystic biliary atresia (CBA) is a rare variant of biliary atresia that closely resembles choledochal cyst (CC), complicating diagnosis and potentially delaying critical surgical intervention. We report two cases of CBA that were difficult to diagnose.
Hamza Hassan Khan, Leslie Hirsig Spence, Nagraj Kasi   +2 more
wiley   +1 more source