Results 91 to 100 of about 38,036 (248)
JTCVS OpenObjectives: Despite its widespread use, spontaneous ventilation can lead to intraoperative hypoxemia or hypercapnia. In this retrospective study, we developed and validated a preoperative clinical data-based model to predict intraoperative hypoxemia or ...
Xiaohan Ren, BS +7 more
doaj +1 more source
Anaesthetic management of a horse with acute kidney injury
Equine Veterinary Education, EarlyView.Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley +1 more source
Long-term DNA methylation changes induced by age and elevated CO2 in skeletal muscle
Skeletal MuscleBackground Skeletal muscle dysfunction and elevated CO2 in the blood, or hypercapnia, are both associated with higher mortality in acute and chronic pulmonary diseases.
Joseph Balnis +7 more
doaj +1 more source
Advanced Biomedical Research, 2014 Background: A retrospective study has shown lesser days of hospital stay in patients with increased levels of intra-operative end-tidal carbon dioxide (ETCO 2 ).
Mahmoud Saghaei +2 more
doaj +1 more source
The FEBS Journal, EarlyView.A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong +6 more
wiley +1 more source
Immunology &Cell Biology, EarlyView.Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan +5 more
wiley +1 more source
Global Warming and Mass Extinctions Associated With Large Igneous Province Volcanism
Geophysical Monograph Series, Page 83-102., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
David P. G. Bond, Yadong Sun
wiley +1 more source
Influence of hypercapnia and hypercapnic hypoxia on the heart rate response to apnea
Physiological ReportsWe aimed to determine the relative contribution of hypercapnia and hypoxia to the bradycardic response to apneas. We hypothesized that apneas with hypercapnia would cause greater bradycardia than normoxia, similar to the response seen with hypoxia, and ...
Benjamin R. O'Croinin +5 more
doaj +1 more source
Journal of Evidence-Based Medicine, EarlyView.ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li +7 more
wiley +1 more source
A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing [PDF]
, 2008 Acid-sensitive K+ channels of the tandem P-domain K+-channel family (TASK-1 and TASK-3) have been implicated in peripheral and central respiratory chemosensitivity; however, because of the lack of decisive pharmacological agents, the final proof of the ...
Gourine, A. V. +3 more
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