Results 91 to 100 of about 27,845 (231)

Cerebrovascular regulation during heat stress

Experimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Hypercapnia and lung function parameters in chronic obstructive pulmonary disease

BMC Pulmonary Medicine
Background In advanced chronic obstructive pulmonary disease (COPD), hypercapnia may occur due to severe bronchial obstruction with lung hyperinflation.
Lukas Gernhold, Claus Neurohr, Konstantinos Tsitouras, Nina Lutz, Selina Briese, Alessandro Ghiani   +5 more
doaj   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response

Respiratory Research
After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to hypercapnia of five CCHS patients with or ...
Caroline Sevoz-Couche, Maxime Patout, Beny Charbit, Thomas Similowski, Christian Straus   +4 more
doaj   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

The Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova, Yiwen Jiang, Helena Wallin, Mats Jensen‐Urstad, Nikola Drca, Julia Röja, Marjan Pontén, Abram Katz, Jonna Nilsson, Maria M. Ekblom, Marcus Moberg   +10 more
wiley   +1 more source

Ventilatory and cerebrovascular responses to exercise in lowlander children acclimatizing to high‐altitude

The Journal of Physiology, EarlyView.
Abstract figure legend To investigate age‐related differences in ventilatory and cerebrovascular responses to exercise at high‐altitude, adults (n = 10, 23–44 years) and children (n = 8, 7–14 years) completed progressive cycling exercise tests at sea‐level and following 6 days of acclimatization at 3800 m.
J. L. Koep, M. G. Rieger, K. J. Smith, G. R. DuManoir, C. M. Tallon, D. R. Perkins, S. Piombo, M. Stembridge, D. M. Cooper, S. Radom‐Aizik, P. N. Ainslie, A. M. McManus   +11 more
wiley   +1 more source

Hypercapnia at Hospital Admission as a Predictor of Mortality

Open Access Emergency Medicine, 2020
Sandy Vonderbank, Natalie Gibis, Alina Schulz, Mariya Boyko, Annika Erbuth, Hakan Gürleyen, Andreas Bastian Marienkrankenhaus Kassel, Kassel, GermanyCorrespondence: Andreas BastianMarienkrankenhaus Kassel, Kassel, GermanyTel +49 561 8073 1212Fax +49
Vonderbank S, Gibis N, Schulz A, Boyko M, Erbuth A, Gürleyen H, Bastian A   +6 more
doaj  

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source