Results 121 to 130 of about 38,999 (275)

Nicotinic Receptor Activation Occludes Purinergic Control of Central Cardiorespiratory Network Responses to Hypoxia/Hypercapnia

, 2007
Prenatal nicotine exposure alters the cardiorespiratory network responses to hypoxia/hypercapnia; however the mechanism(s) responsible for these cardiorespiratory network responses and their alteration by prenatal nicotine exposure are unknown.
Z. G. Huang, X. Wang, D. Mendelowitz, Kamendi, H., O. Dergacheva, H. Kamendi, Gorini, C., C. Gorini, Dergacheva, O., Huang, Z. G., K. J. S. Griffioen, Wang, X., Mendelowitz, D., Griffioen, K. J.S.   +13 more
core   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

Experimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto, Rintaro Sakamoto, Darren P. Casey   +2 more
wiley   +1 more source

Acute exercise‐induced improvements in cognition: Role of cerebral blood flow and metabolism

Experimental Physiology, EarlyView.
Abstract Physical activity is widely recognized for its ability to promote brain health, with acute exercise transiently enhancing cognition and long‐term training attenuating cognitive decline. However, the mechanisms underlying these benefits remain incompletely understood.
Takeshi Hashimoto, Shigehiko Ogoh
wiley   +1 more source

Hypercapnia and lung function parameters in chronic obstructive pulmonary disease

BMC Pulmonary Medicine
Background In advanced chronic obstructive pulmonary disease (COPD), hypercapnia may occur due to severe bronchial obstruction with lung hyperinflation.
Lukas Gernhold, Claus Neurohr, Konstantinos Tsitouras, Nina Lutz, Selina Briese, Alessandro Ghiani   +5 more
doaj   +1 more source

Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective

Experimental Physiology, EarlyView.
Abstract Cerebral blood flow (CBF) is essential for sustaining neuronal metabolism and cognitive performance; however, the precise relationship between perfusion and cognition remains unclear. Although ageing and disease are associated with progressive declines in CBF and cognitive impairment, the acute effects of altered CBF under environmental ...
Hiroki Nakata, Shigehiko Ogoh, Manabu Shibasaki   +2 more
wiley   +1 more source

Effects of indomethacin on cerebral blood flow during hypercapnia in cats

, 1983
To study the contribution of prostaglandins to cerebral vasodilatation during hypercapnia, we inhibited prostaglandin synthesis with indomethacin.
D. W. Busija, D. D. Heistad
core   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Higher baseline heart rate variability in CCHS patients with progestin-associated recovery of hypercapnic ventilatory response

Respiratory Research
After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to hypercapnia of five CCHS patients with or ...
Caroline Sevoz-Couche, Maxime Patout, Beny Charbit, Thomas Similowski, Christian Straus   +4 more
doaj   +1 more source

Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study

Experimental Physiology, EarlyView.
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey, Richard G. Davies, Brenig L. Gwilym, Benjamin S. Stacey, Danny Walmsley, Michael H. Lewis, Josip Butkovic, Ivan Mumlek, Brad Perry, Zvonomir Vrselja, Shigehiko Ogoh, James A. Pawelczyk, Mohamad Bashir, Richard D. White, Ian M. Williams   +14 more
wiley   +1 more source