Results 151 to 160 of about 180,738 (304)

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source

The Multidimensional Burden of COPD in China: A Propensity Score-Matched Comparison with Other Prevalent Non-Communicable Diseases. [PDF]

Int J Chron Obstruct Pulmon Dis
Sun Q, Lu B, Chen Q, Zheng Z.
europepmc   +1 more source

The Australia and New Zealand Diabetic and Ischaemic Foot Outcomes Study (ANZDIFOS)

ANZ Journal of Surgery, EarlyView.
ABSTRACT Objective There is limited high‐quality data on the factors that contribute to limb loss in patients with diabetes‐related foot disease (DFD) in New Zealand and Australia. Furthermore, wound, ischaemia and foot infection (WIfI) staging has not been validated in the Australasian cohort.
Odette Hart, Philip Allan, Shirley Jansen, Robert Fitridge, Claire Murray, Mendel Baba, Prue Cowled, Neil McMillan, Manar Khashram   +8 more
wiley   +1 more source

Positive Predictive Values of Familial Hypercholesterolemia Diagnoses in the Danish National Patient Registry and the Danish Familial Hypercholesterolemia Registry - A Validation Study. [PDF]

Clin Epidemiol
Knold J, Bork C, Snoer M, Heitmann M, Bang LE, Kanstrup H, Hansen KL, Hedegaard BS, Thomsen KK, Lauridsen BK, Bovin A, Lundquist AA, Al Tamimi HKS, Brorholt-Petersen JU, Christensen TE, Bertelsen MLN, Gohr T, Ellermann A, Hansen CP, Weis A, Nielsen PR, Schmidt EB, Bundgaard H, Henriksen FL, Danish Familial Hypercholesterolemia Study Group.   +24 more
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Hypercholesterolemia Impairs the Expression of Angiogenic MicroRNAs in Extracellular Vesicles Within Ischemic Skeletal Muscles. [PDF]

Noncoding RNA
Raguema N, Dussault S, Sawaya K, Desjarlais M, Boilard E, Chemtob S, Rivard A.   +6 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Impact of Monacolin K-Containing Supplements on Lipid Profile: A Meta-Analysis of Randomised Controlled Trials. [PDF]

Endocrinol Diabetes Metab
Jamialahmadi T, Mirhadi E, Karav S, Kesharwani P, Sahebkar A.   +4 more
europepmc   +1 more source

Cardiometabolic Risk in First Degree Relatives of Women With Polycystic Ovary Syndrome (PCOS)

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a common multisystem disorder with reproductive, cardiometabolic and psychological implications. Genetic factors play a role in the pathogenesis of PCOS. We sought to investigate the cardiometabolic health of first degree relatives (FDR) of women with PCOS.
Su Jen Chua, Xinyi Wu, Tahani Al Kindi, Bulent O. Yildiz, Aya Mousa, Loyal Pattuwage, Helena Teede, Anju E. Joham, Chau Thien Tay   +8 more
wiley   +1 more source

The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta-Analysis and Trial Sequential Analysis. [PDF]

Cardiovasc Ther
Wang S, Li C, Fan D.
europepmc   +1 more source