Results 61 to 70 of about 182,065 (262)

Safety and Effectiveness of Low‐Density Lipoprotein Cholesterol–Lowering Therapy With Evolocumab for Familial Hypercholesterolemia/Hypercholesterolemia in Japan: A Real‐World, Postmarketing, Single‐Arm Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evolocumab is the first monoclonal antibody against proprotein convertase subtilisin/kexin type 9 approved in Japan for familial hypercholesterolemia (FH) and hypercholesterolemia; however, data on its safety and effectiveness in the real ...
Koutaro Yokote, Junya Ako, Kazuo Kitagawa, Nobuhiro Osada, Feng Sheng, Masae Sonoda, Tamio Teramoto   +6 more
doaj   +1 more source

In Vitro and in Vivo Evaluation of Novel Cross-Linked Saccharide Based Polymers as Bile Acid Sequestrants

Molecules, 2015
Bile acid sequestrants (BAS) represent a therapeutic approach for the management of hypercholesterolemia that relies on the cationic polymeric nature of BAS to selectively bind negatively charged bile acids.
Francisco Javier Lopez-Jaramillo, Maria Dolores Giron-Gonzalez, Rafael Salto-Gonzalez, Fernando Hernandez-Mateo, Francisco Santoyo-Gonzalez   +4 more
doaj   +1 more source

Overweight and Obesity-related Metabolic Disorders in Hospital Employees

Journal of the Formosan Medical Association, 2006
Obesity is associated with metabolic disorders and cardiovascular diseases. This study investigated the relationship between overweight and obese status and the incidence of type 2 diabetes, hypertension, hyperlipidemia and hyperuricemia.
Lee-Ching Hwang
doaj   +1 more source

Modulatory effects of rutin on biochemical and hematological parameters in hypercholesterolemic Golden Syrian hamsters

Anais da Academia Brasileira de Ciências, 2009
Flavonoids have been reported to exhibit several pharmacological properties, mainly in cardiovascular and inflammatory diseases. In the present study, we observed that rutin, a known glycosylated flavonoid isolated from Dimorphandra mollis, had a ...
Alexandre Kanashiro, Daiani C.O. Andrade, Luciana M. Kabeya, Walter M. Turato, Lucia H. Faccioli, Sérgio A. Uyemura, Yara M. Lucisano-Valim   +6 more
doaj   +1 more source

Carotid Atherosclerotic Markers in CADASIL [PDF]

, 2011
Purpose: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a cerebral small vessel disease caused by mutations of the NOTCH3 gene. Marked variations in disease severity have raised the hypothesis that
Aout, Mounir, Chabriat, Hugues, Dichgans, Martin, Düring, Marco, Mawet, Jerome, Touboul, Pierre Jean, Vahedi, Katayoun, Vicaut, Eric   +7 more
core   +1 more source

Effect of the proprotein convertase subtilisin/kexin type 9 inhibitor evolocumab on glycemia, body weight, and new-onset diabetes mellitus [PDF]

, 2017
Statin therapy modestly increases new-onset diabetes risk. The effect of proprotein convertase subtilisin/kexin type 9 inhibition on new-onset diabetes, glycemia, and weight remains unclear.
Blom, Dirk J., Cyrille, Marcoli, Elliott, Mary, Koren, Michael J., Preiss, David, Sattar, Naveed, Somaratne, Ransi, Soran, Handrean, Toth, Peter P., Uhart, Magdalena   +9 more
core   +1 more source

Atherocalcinosis of the arterial wall and its association with disorder of blood lipoprotein profile, mineral exchange and structural changes of achilles tendon (according to computer tomography data)

Атеросклероз, 2020
The purpose of the study was to study the possible association of hyperlipidemia, atherosclerosis and calcification of the arterial wall with the structural features of Achilles tendons. Material and methods.
A. V. Anikina, Yu. P. Nikitin, M. E. Amelin   +2 more
doaj   +1 more source

The prevalence of cardiovascular disease risk factors in patients from Croatian Zagorje County treated at Department of Medicine, Zabok General Hospital from 2000 to 2006 [PDF]

, 2007
The aim of the study was to assess the prevalence of risk factors for cardiovascular disease in patients treated for coronary heart disease (CHD) at Department of Medicine, Zabok General Hospital during the 2000-2006 period. Cardiovascular diseases are a
Buković, Damir, Fureš, Rajko, Pešek, Ksenija, Pešek, Tomislav, Radoš, Marko, Ćuk, Višeslav   +5 more
core  

Smoking affects gene expression in blood of patients with ischemic stroke. [PDF]

, 2019
ObjectiveThough cigarette smoking (CS) is a well-known risk factor for ischemic stroke (IS), there is no data on how CS affects the blood transcriptome in IS patients.MethodsWe recruited IS-current smokers (IS-SM), IS-never smokers (IS-NSM), control ...
Ander, Bradley P, Cheng, Xiyuan, Ferino, Eva, Hull, Heather, Jickling, Glen C, Sharp, Frank R, Stamova, Boryana   +6 more
core   +2 more sources

Peculiarities of Lipid Metabolism in Patients with Prolactinomas during Suppressive Dopamine Agonist Therapy

Mìžnarodnij Endokrinologìčnij Žurnal, 2015
The article presents the data of lipid metabolism at the stages of long-term (12 months) suppressive therapy with dopamine agonist cabergoline in 61 patients with prolactinoma.
T.H. Hohitidze
doaj   +1 more source