Prognostic benefit of immunosuppressive agents in primary Sjögren’s syndrome patients with hypergammaglobulinemia [PDF]
Frontiers in ImmunologyObjectiveTo elucidate the prognosis of patients with primary Sjögren’s syndrome (pSS) accompanied by hypergammaglobulinemia (HG), with a particular focus on the impact of various treatments.MethodsPatients were divided into the HG group and the non-HG ...
Liupan Zhang +8 more
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Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association [PDF]
Clinical, Cosmetic and Investigational DermatologyFabrizio Martora,* Teresa Battista,* Antonella Giordano, Luca Potestio, Matteo Megna Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy*These authors contributed equally to this ...
Martora F +4 more
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Etiological study of polyclonal hypergammaglobulinemia in a French cohort of hospitalized patients and proposal of a diagnostic aid algorithm [PDF]
Scientific ReportsSerum protein electrophoresis can sometimes reveal polyclonal hypergammaglobulinemia. This electrophoretic abnormality can be caused by a variety of conditions and can be difficult to investigate.
Mallory ANDRE +2 more
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Impact of Sjögren’s disease and its immunological characteristics on reaching remission or low disease activity state in systemic lupus erythematosus patients: a propensity score-matched longitudinal study [PDF]
Frontiers in ImmunologyBackgroundSystemic lupus erythematosus (SLE) overlapping with Sjögren’s disease (SjD) or not may progress differently in the clinical course. We aimed to explore the impact of SjD on lupus low disease activity state (LLDAS) or remission achievement in a ...
Haoze Zhang +5 more
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Early-onset systemic lupus erythematosus in a patient with an inborn error of immunity caused by a NRAS mutation and treated with telitacicept [PDF]
Molecular and Cellular PediatricsHere, we report a female (aged 1 year and 8 months) who presented with recurrent skin lesions, hepatosplenomegaly, lymphadenopathy, and fever.
Zhijuan Kang, Liang Zhang
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Variable clinical features and delayed diagnosis in six Chinese patients with anti-interferon-gamma autoantibodies: a retrospective analysis in a university hospital in China [PDF]
BMC ImmunologyBackground Anti-interferon (IFN)-gamma (γ) autoantibody positivity (AIGA) is a rare cause of adult-onset immunodeficiency, leading to severe disseminated opportunistic infections with varying outcomes.
Junwu Zhang +4 more
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Diagnostic Challenge in a Patient Presenting with Ascites and Hypergammaglobulinemia
Case Reports in Gastroenterology, 2021 Ascites is defined as the accumulation of intra-peritoneal fluid that can be caused by several diseases. We described a 47-year-old female presenting with low serum-ascites albumin gradient (SAAG) and a markedly high level of serum globulin.
Syifa Mustika +2 more
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Idiopathic multicentric Castleman disease presenting progressive reticular honeycomb infiltration of lung and immunoglobulin G and immunoglobulin G4 dominant hypergammaglobulinemia: a case report [PDF]
Journal of Yeungnam Medical Science, 2022 Multicentric Castleman disease (MCD) is an uncommon systemic lymphoproliferative disorder that may cause multiple organ damage. Castleman disease-associated diffuse parenchymal lung disease (DPLD) has not been well studied. A 32-year-old man was referred
Hyun-Je Kim, Young-Hoon Hong
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Immunoglobulin G: A useful outcome marker in the follow‐up of cystic fibrosis patients?
Immunity, Inflammation and Disease, 2021 Background and Methods Hypergammaglobulinemia (hyper‐IgG) and hypogammaglobulinemia (hypo‐IgG) have been reported in patients with cystic fibrosis (CF).
Laurence S. Hanssens +3 more
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BMC Infectious Diseases, 2021 Background Kidney involvement of visceral Leishmaniasis is previously reported, but knowledge is limited. Hypergammaglobulinemia is common in visceral leishmaniasis patients.
Linfeng Zou +6 more
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