Etiological study of polyclonal hypergammaglobulinemia in a French cohort of hospitalized patients and proposal of a diagnostic aid algorithm [PDF]
Scientific ReportsSerum protein electrophoresis can sometimes reveal polyclonal hypergammaglobulinemia. This electrophoretic abnormality can be caused by a variety of conditions and can be difficult to investigate.
Anne Contis
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Hypergammaglobulinemia in treated and untreated people with HIV. [PDF]
PLoS ONEBackgroundB cell abnormalities are an early feature of human immunodeficiency virus-1 (HIV) infection, leading to hypergammaglobulinemia.Objective(s)The aim of this study was to evaluate serum levels of immunoglobulin G (IgG) as well as the inflammatory ...
Isabel Vigmo +5 more
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Prognostic benefit of immunosuppressive agents in primary Sjögren’s syndrome patients with hypergammaglobulinemia [PDF]
Frontiers in ImmunologyObjectiveTo elucidate the prognosis of patients with primary Sjögren’s syndrome (pSS) accompanied by hypergammaglobulinemia (HG), with a particular focus on the impact of various treatments.MethodsPatients were divided into the HG group and the non-HG ...
Liupan Zhang +8 more
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Interfollicular Plasmacytosis and Hyperplastic Germinal Centers in Idiopathic Multicentric Castleman Disease, Idiopathic Plasmacytic Lymphadenopathy Subtype. [PDF]
Am J HematolAmerican Journal of Hematology, Volume 101, Issue 6, Page 1269-1272, June 2026.
Quon S +5 more
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Hypergammaglobulinemia in the pediatric population [PDF]
Pediatric Rheumatology Online Journal, 2012 Purpose Hypergammaglobulinemia in adult patients is usually related to malignancy, autoimmune disease, or infection. The differential diagnosis of hypergammaglobulinemia in children has not been similarly well defined. Malignancies and autoimmunity are much less common in children compared to the adult population, and therefore the implications of an ...
Lo Mindy S, Sundel Robert P
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EXPERIMENTAL HYPERGAMMAGLOBULINEMIA IN MINK [PDF]
Journal of Experimental Medicine, 1962 Hypergammaglobulinemia in mink was produced by the injection of crude tissue suspensions from mink with spontaneous Aleutian disease. The initiating factor was found to be resistant to 0.3 per cent formalin for 2 weeks but not 40 weeks at 5°C. Foreign antigens as well as formalinized normal mink tissue from homologous and heterologous genotypes did not
J R Gorham, J B Henson, Gorham John R
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Impact of Sjögren’s disease and its immunological characteristics on reaching remission or low disease activity state in systemic lupus erythematosus patients: a propensity score-matched longitudinal study [PDF]
Frontiers in ImmunologyBackgroundSystemic lupus erythematosus (SLE) overlapping with Sjögren’s disease (SjD) or not may progress differently in the clinical course. We aimed to explore the impact of SjD on lupus low disease activity state (LLDAS) or remission achievement in a ...
Haoze Zhang +5 more
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Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association [PDF]
Clinical, Cosmetic and Investigational DermatologyFabrizio Martora,* Teresa Battista,* Antonella Giordano, Luca Potestio, Matteo Megna Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy*These authors contributed equally to this ...
Martora F +4 more
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Early-onset systemic lupus erythematosus in a patient with an inborn error of immunity caused by a NRAS mutation and treated with telitacicept [PDF]
Molecular and Cellular PediatricsHere, we report a female (aged 1 year and 8 months) who presented with recurrent skin lesions, hepatosplenomegaly, lymphadenopathy, and fever.
Zhijuan Kang, Liang Zhang
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Diagnostic Challenge in a Patient Presenting with Ascites and Hypergammaglobulinemia
Case Reports in Gastroenterology, 2021 Ascites is defined as the accumulation of intra-peritoneal fluid that can be caused by several diseases. We described a 47-year-old female presenting with low serum-ascites albumin gradient (SAAG) and a markedly high level of serum globulin.
Syifa Mustika +2 more
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