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Potassium‐Competitive Acid Blocker‐Associated Gastric Hyperplastic Polyps With Severe Bleeding: A Case Series [PDF]

open access: yesDEN Open
Gastric hyperplastic polyps can cause gastrointestinal bleeding, and their enlargement has been associated with long‐term acid‐suppressive therapy. Vonoprazan (VPZ), a potassium‐competitive acid blocker, provides potent acid suppression and may induce ...
Kengo Kasuga   +9 more
doaj   +3 more sources

The Autoimmune Gastritis Puzzle: Emerging Cellular Crosstalk and Molecular Pathways Driving Parietal Cell Loss and ECL Cell Hyperplasia [PDF]

open access: yesCells
Autoimmune gastritis (AIG) is a chronic, organ-specific autoimmune disease characterized by progressive destruction of gastric parietal cells driven by autoreactive CD4+ T-cells, epithelial stress pathways, and microbial factors.
Sara Massironi   +4 more
doaj   +2 more sources

Current Medical Controversies in Zollinger–Ellison Syndrome [PDF]

open access: yesBiomedicines
Purpose: Zollinger–Ellison syndrome (ZES) is the most frequent, functional, malignant pancreatic neuroendocrine tumor syndrome (pNET), which is due to ectopic secretion of gastrin by a pNET/NET (i.e., gastrinomas) resulting in severe, refractory acid ...
Robert T. Jensen   +2 more
doaj   +2 more sources

Hypergastrinemia in Children : A Case Report

open access: yesArchives of Pediatric Gastroenterology, Hepatology, and Nutrition, 2022
Gastrin is an important hormone in the gastrointestinal system that promotes gastric acid secretion. Gastrin hormone is produced by the G-cells in the antrum of the stomach.
Edbert Wielim   +2 more
doaj   +2 more sources

Revealing autoimmune gastritis: Polypoid nodule scar development after endoscopic submucosal dissection for early gastric cancer [PDF]

open access: yesDEN Open
Endoscopic submucosal dissection (ESD), the standard treatment for early gastric cancer, typically results in homogeneous flat scars. However, in some cases, polypoid nodule scars (PNS) may develop, complicating the cancer recurrence assessment.
Naoya Masuda   +7 more
doaj   +2 more sources

Diarrhea, Weight Loss, and an Elevated Gastrin: A Case Report [PDF]

open access: yesCase Reports in Gastroenterology
Introduction: Hypergastrinemia in a patient with refractory reflux, steatorrhea, or peptic ulcer disease with a gastric pH <4 is concerning for Zollinger-Ellison syndrome (ZES), but antral G-cell hyperplasia can also present in this manner ...
Ryan G. Alexander   +3 more
doaj   +2 more sources

Disappearance of Gastric Hyperplastic Polyps after the Discontinuation of Proton Pump Inhibitor in a Patient with Liver Cirrhosis

open access: yesCase Reports in Gastroenterology, 2021
Here, we report on a rare case of gastric hyperplastic polyps which disappeared after the discontinuation of proton pump inhibitor (PPI). The patient was an 83-year-old woman with liver cirrhosis and portal hypertension, along with gastroesophageal ...
Kengo Yasugi   +10 more
doaj   +1 more source

Hypergastrinemia [PDF]

open access: yesGastroenterology Report, 2015
Gastrin is an important hormone of the digestive system, which assists gastric acid secretion. It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to common medications such as proton pump inhibitors. In this review we provide an overview of the pathophysiology and medical causes of hypergastrinemia, diagnostic ...
Dacha, Sunil   +4 more
openaire   +2 more sources

Proton Pump Inhibitors and Gastric Cancer [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2021
Concerns have been raised regarding the long-term use of proton pump inhibitors (PPIs) as an important risk factor for gastric cancer in clinical practice.
Seungkyung Kang, Soo-Jeong Cho
doaj   +1 more source

Gastrin and the Moderate Hypergastrinemias [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The antral hormone gastrin potently regulates gastric acid secretion and fundic mucosal growth. Consequently, appropriate gastrin secretion and plasma concentrations are important for the early phases of digestion. This review describes as the first premise the normal biogenesis of gastrin in the antral mucosa, but also mentions the extraantral ...
openaire   +4 more sources

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