Results 21 to 30 of about 2,368 (175)

A Five-Year-Old Boy with Marked Hypergastrinemia Associated with H. pylori Infection

Case Reports in Gastroenterology, 2010
A 5-year-old boy was referred to our department for persistent epigastric discomfort. Serum gastrin level was 635 pg/ml with a pepsinogen (PG) I level of 102.7 ng/ml and a PG I/II ratio of 23.2, indicating a hyperacidic state.
Asako Nakata, Hitoshi Tajiri, Yuri Etani, Sadami Kimura, Tomoko Takano   +4 more
doaj   +1 more source

Zollinger-Ellison Syndrome: A Narrative Review of Clinical Presentation, Pathogenesis, Diagnosis and Modern Management Approaches [PDF]

Journal of Clinical and Diagnostic Research
Zollinger-Ellison Syndrome (ZES) is rare disorder which is caused by gastrin-secreting neuroendocrine tumours known as gastrinomas, primarily located in the duodenum or pancreas.
Jaideep Reddy, Raju Shinde, Khushbu Vaidya, Prithvansh Malhotra, Bhagyesh Sapkale   +4 more
doaj   +1 more source

Decision analysis in evaluation of hypergastrinemia

The American Journal of Medicine, 1986
Hypergastrinemia and gastric acid hypersecretion are the principal laboratory features of Zollinger-Ellison syndrome. Decision and cost-effectiveness analyses were employed in the present study to compare and contrast the diagnostic strategies of initial gastric analysis followed by secretin infusion test versus secretin infusion test alone in the ...
Division of Gastroenterology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA ( host institution ), Spindel, Enrique, Harty, Richard F., Leibach, John R., McGuigan, James E.   +4 more
openaire   +5 more sources

Well-Differentiated Grade 1 Gastric Neuroendocrine Tumor Occurring 11 Years After Pernicious Anemia [PDF]

Batna Journal of Medical Sciences
Type I gastric neuroendocrine tumors (GNETs) are closely associated with autoimmune atrophic gastritis, particularly pernicious anemia. They arise as a consequence of chronic hypergastrinemia, which induces enterochromaffin- like cell hyperplasia and ...
Aicha CHERIF HOSNI,, Yasmina RAHAL, Fatima Zohra ABDELOUAHAB, Imene TASSA, Imene ZIOUANI, Reda MESSAOUDI   +5 more
doaj   +1 more source

Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects

Frontiers in Pharmacology, 2021
Potassium-competitive acid blocker is a new class of drugs inhibiting gastric acid. It is controversial that vonoprazan showed the inhibitory activities of cytochrome P450 3A4.
Sejung Hwang, Jae-Wook Ko, Heechan Lee, Seokuee Kim, Bongtae Kim, Geun Seog Song, Jungryul Kim, Jungryul Kim   +7 more
doaj   +1 more source

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1363-1371, September 2026.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales, Benjamin W. Sykes, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Serum gastrin concentrations in dogs with primary hyperparathyroidism

Journal of Veterinary Internal Medicine
Background Hypercalcemia has been associated with hypergastrinemia in humans. Hypergastrinemia could be responsible for gastrointestinal (GI) signs in dogs with primary hyperparathyroidism (PHPT).
Julieann Vose, Jared Jaffey, Camille Akin, Alexander Spitzer, Barry DeCicco, Enass Bassiouny, Ashley LaClair, Brian Petroff, Jean Brudvig, Harry Cridge   +9 more
doaj   +1 more source

Factors associated with elevated serum chromogranin A levels in patients with autoimmune gastritis

The Turkish Journal of Gastroenterology, 2016
Background/Aims: Chromogranin A is an important tool in the diagnosis of neuroendocrine tumors. Autoimmune gastritis is an autoimmune disorder marked by hypergastrinemia, which stimulates enterochromaffin-like cell proliferation.
Çağdaş Kalkan, Fatih Karakaya, İrfan Soykan   +2 more
doaj   +1 more source

Neuroendocrine tumors of the stomach and H. pylori infection: features of patient monitoring on the example of a clinical case

Клинический разбор в общей медицине
In this clinical case, we present an observation of a 36-year-old patient with a highly differentiated neuroendocrine tumor (NEO) of the stomach (NET G2, Ki-67.7%), which developed against the background of autoimmune gastritis and persistent infection ...
Margarita D. Kozlova, Margarita D. Kozlova, Ilya I. Kovrigin, Natalya N. Dekhnich, Natalya N. Dekhnich   +4 more
doaj   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source