Results 161 to 170 of about 9,846 (249)

ProteinWeaver: A webtool to visualize ontology-annotated protein networks. [PDF]

PLoS One
Anderson O, Barelvi A, O'Brien A, Norman A, Jan I, Ritz A.   +5 more
europepmc   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, Volume 13, Issue 14, 9 March 2026.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Directing stem cell differentiation by chromatin state approximation. [PDF]

Nucleic Acids Res
Montano-Gutierrez LF, Müller S, Kutschat AP, Adameyko I, Seruggia D, Halbritter F.   +5 more
europepmc   +1 more source

Population and single‐cell analyses reveal immune cell‐specific expression profiles associated with Alzheimer's disease risk

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Dysregulation of the peripheral immune system may increase Alzheimer's disease (AD) risk, but the underlying cell type‐specific mechanisms remain unclear. METHODS We conducted Mendelian randomization and colocalization analyses of 4489 genes using single‐cell expression quantitative trait locus data from unstimulated and ...
Joni V. Lindbohm, Martin Stražar, Hang‐Mao Lee, Orr Ashenberg, Nina Mars, Pyry N. Sipilä, Samuli Ripatti, Dan Graham, Mika Kivimäki, Ramnik J. Xavier   +9 more
wiley   +1 more source

Histone methyltransferase Setd8 preserves chromatin accessibility to safeguard retinal progenitor cell identity during development. [PDF]

Stem Cell Reports
Sekiryu H, Shimokawa S, Matsuda-Ito K, Oda H, Murakami Y, Sonoda KH, Nakashima K, Matsuda T.   +7 more
europepmc   +1 more source

A New Padé Approach to Modeling Wormholes in Dekel‐Zhao Dark Matter Halos

Annalen der Physik, Volume 538, Issue 3, March 2026.
A matter‐first Padé strategy is introduced to build traversable wormholes from prescribed dark‐matter halos. Rational Padé fits approximately the Dekel–Zhao density and are analytically integrated to obtain a shape function that exactly reproduces the intended matter content, avoiding spurious poles of geometry‐first schemes.
Jonathan Alves Rebouças, Francisco Tiago Barboza Sampaio, Francisco Bento Lustosa, Leonardo Tavares de Oliveira, C. R. Muniz   +4 more
wiley   +1 more source

Cellular reprogramming of H3K27M pediatric high-grade glioma to neuron-like state. [PDF]

Acta Neuropathol Commun
Uthamacumaran A, Horth C, Bareke E, Gravel M, Majewski J.   +4 more
europepmc   +1 more source

Evaluating Aversion to Eye‐Like Stimuli as a Foraging Deterrent in Urban European Herring Gulls

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We tested whether eye‐like and high contrast patterns on takeaway food boxes deterred urban herring gulls from approaching and pecking at food boxes. Gulls were slower to approach and less likely to peck at boxes with eyes, and the deterrent effect persisted in the short‐term for some gulls. When used alongside other deterrents, eye‐like stimuli may be
Laura A. Kelley, Rosa Hunter Thompson, Beth Rowe, Neeltje J. Boogert   +3 more
wiley   +1 more source

SEdb 3.0: a comprehensive super-enhancer database across multiple species. [PDF]

Nucleic Acids Res
Song S, Liu L, Feng C, Xie L, Zhang G, Zhang Y, Gao Y, Yin M, Tang X, Pei W, Song C, Liu R, Li C.   +12 more
europepmc   +1 more source

Widely Targeted Metabolomics Reveals Differences in Secondary Metabolites in Oats With Different Grain Hardness

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
UHPLC–MS/MS and metabolomics revealed 409 differentially accumulated secondary metabolites between hard (HX320) and soft (HX317) oat cultivars. Key flavonoids, cirsilineol and swertiajaponin, showed synergistic effects potentially modulating reactive oxygen species.
Daxiao Zhang, Huiyan Liu, Ying Guo, Guanyu Chen, Meilin Chen, Xian Xian, Yuehua Zhang, Bing Han   +7 more
wiley   +1 more source