Results 31 to 40 of about 188,311 (274)
Clinical Cardiology, Volume 45, Issue 12, Page 1246-1254, December 2022., 2022 Abstract Background and Hypothesis Glycemic variability in one fact that explain the differences in cardiovascular outcomes. The short‐term fasting plasma glucose (FPG) variability may have an on major adverse cardiovascular events (MACE) in type 2 diabetes mellitus (T2DM) patients with ST‐segment elevation myocardial infarction (STEMI).
Ming Yi +4 more
wiley +1 more source
Advanced Science, EarlyView.In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang +10 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1449-1455, December 2022., 2022 Abstract Objectives The extraction of a tooth exacerbates the stress in diabetic patients leading to diabetic complications so the aim was to evaluate the changes in blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction to pay special attention during a routine surgical procedure.
Zana Agani +6 more
wiley +1 more source
Hypoxia-inducible factor 1a protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species [PDF]
arXiv, 2018 Diabetic peripheral neuropathy (DPN) is one of the most common diabetic complications. Mechanisms underlying nerve damage and sensory loss following metabolic dysfunction remain large unclear. Recently, hyperglycemia-induced mitochondrial dysfunction and the generation of ROS have gained attention as possible mechanisms of organ damage in diabetes ...
arxiv
Indian Journal of Endocrinology and Metabolism, 2012 Isolated post prandial hyperglycaemia (PPHG) has been shown to double the risk for cardiovascular mortality. It also makes a significant contribution to overall glycaemia reflected in the HbA1c level. The harmful effects of PPHG are increased cardiovascular mortality, association with mic rovascular complications, cognitive decline and cancers.
openaire +4 more sources
Engineering the Immune Response to Biomaterials
Advanced Science, EarlyView.This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam +12 more
wiley +1 more source
Diabetes/Metabolism Research and Reviews, Volume 39, Issue 1, January 2023., 2023 Abstract Background Women with type 1 diabetes (T1D) are more susceptible than men to cardiovascular disease (CVD). Signs of increased risk may already appear among adolescent girls. Objectives We explored the contribution of body composition to the development of CVD risk factors among youth with T1D.
Avivit Brener +10 more
wiley +1 more source
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia‐Induced Vascular Injury
Advanced Science, EarlyView.Mitophagy switching drives high‐glucose‐induced vascular endothelial injury. Short‐term high‐glucose exposure upregulates Fis1 expression and enhances Fis1‐TBC1D15 interaction, activating Parkin‐mediated mitophagy. Long‐term high‐glucose exposure reduces Fis1 expression, inhibiting Parkin‐mediated mitophagy and triggering mitophagy switching from ...
Anqi Luo +10 more
wiley +1 more source
Advanced Science, EarlyView.These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma +12 more
wiley +1 more source
Type 1 diabetes recurrence after SARS‐CoV‐2 infection in a subject with pancreas transplantation
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV2 infection and diabetes mellitus. Little is known about the effects of SARS‐CoV‐2 infection on glycaemic control in pancreas transplant patients. Abstract Background During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV‐2 ...
Valentina Popolla +4 more
wiley +1 more source