Results 81 to 90 of about 30,982 (276)

Folic Acid and Vitamins B12 Levels and Their Correlation in Cigarette Smoker with Hyperhomocysteinemia [PDF]

Al Ameen Journal of Medical Sciences, 2011
To estimate the levels of folic acid and vitamin B12 and their relationship in cigarette smoker with hyperhomocysteinemia. 30 male cigarette smokers in the age group of 30 to 60 years were studied for estimation of serum folic acid, vitamin B12 and total
Shahid A. Mujawar* and Vinayak W. Patil
doaj  

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks. [PDF]

, 2018
Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability.
Chen, Hongping, Choi, Eric T., Cueto, Ramon, Drosatos, Konstantinos, Fu, Hangfei, Nanayakkara, Gayani K, Park, Joon Y., Qin, Xuebin, Shao, Lijian, Shao, Ying, Sheng, Haitao, Sun, Jianxin, Sun, Yu, Wang, Hong, Wang, Luqiao, Wu, Na, Yang, Qian, Yang, William Y, Yang, Wuping, Yang, Xiaofeng, Zeng, Huihong, Zhu, Qingxian   +21 more
core   +2 more sources

No Increased Risk of Thromboembolic Events During 6‐Month Treatment With Baricitinib in Patients With Alopecia Areata

International Journal of Dermatology, EarlyView.
Giacomo Caldarola, Antonietta Ferretti, Lorenzo Maria Pinto, Leonardo Di Gennaro, Eleonora De Luca, Gennaro Marco Falco, Clara De Simone, Raimondo De Cristofaro, Ketty Peris   +8 more
wiley   +1 more source

The Role of DNA Methyltransferases in Urinary System Diseases

Cancer Innovation, Volume 4, Issue 6, December 2025.
Multiple signaling pathways mediated by DNMTs in the formation of renal fibrosis: (a) DNMTs suppress the expression of transcription factor KLF4 by mediating promoter hypermethylation, thereby promoting epithelial–mesenchymal transition and contributing to the development of renal fibrosis; (b) oxidative stress can upregulate the levels of DNMTs, which
Wei Dong, Shengbin Pei, Dacheng Zhu, Cheng Zeng, Yue Qiu, Yuxin Wu, Xinlu Jia, Siqi Zhang, Chao Li, Wenjuan Zhang, Wenbing Zhang, Zhihua Chen   +11 more
wiley   +1 more source

The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels

Haematologica, 2007
In a large retrospective study of thrombophilic families, we analyzed 405 relatives of patients, hypothesizing that hyperhomocysteinemia and elevated factor VIII levels are closely related. Median factor VIII levels in hyperhomocysteinemic relatives were
Willem M. Lijfering, Nic J.G.M. Veeger, Jan-Leendert P. Brouwer, Jan van der Meer   +3 more
doaj   +1 more source

The Oxidative Stress May be Induced by the Elevated Homocysteine in Schizophrenic Patients [PDF]

, 2012
The mechanisms of oxidative stress in schizophrenic patients are not fully understood. In the present study, we investigated the effect of elevated level of homocysteine (Hcys) on some parameters of oxidative stress, namely thiobarbituric acid ...
Bald, Edward, Dietrich-Muszalska, Anna, Głowacki, Rafał, Malinowska, Joanna, Olas, Beata, Rabe-Jabłońska, Jolanta, Wachowicz, Barbara   +6 more
core   +3 more sources

Hyperhomocysteinemia and Thrombosis: An Overview

Archives of Pathology & Laboratory Medicine, 2007
Abstract Context.—Homocysteine, a sulfur-containing amino acid, absent in natural diets, is a metabolic intermediary in transmethylation and transsulfuration reactions. Such reactions are essential to normal cellular growth, differentiation, and function. Excess homocysteine is associated with vascular disease and related disorders.
Mohamed M, Eldibany, Joseph A, Caprini
openaire   +2 more sources

Antioxidant Potential of Polyphenolic Compounds, Sources, Extraction, Purification and Characterization Techniques: A Focused Review

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This review highlights the antioxidant potential of polyphenolic compounds derived from diverse plant sources. It outlines extraction and purification methods, advanced spectroscopic and chromatographic characterization techniques, and underlying antioxidant mechanisms such as radical scavenging, metal chelation, and signalling modulation.
Zubair Ahmad, Abdur Rauf, Ilkay Erdogan Orhan, Mohammad S. Mubarak, Zuneera Akram, Md. Rezaul Islam, Muhammad Imran, Zehra Edis, Benod Kumar Kondapavuluri, Lakshmi Thangavelu, Muthu Thiruvengadam   +10 more
wiley   +1 more source

Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative atrophic glossitis patients

Journal of the Formosan Medical Association, 2019
Background/Purpose: Approximately 27% of atrophic glossitis (AG) patients have the serum gastric parietal cell antibody (GPCA) positivity. This study assessed whether the serum GPCA or AG itself was a significant factor causing anemia, hematinic ...
Chun-Pin Chiang, Julia Yu-Fong Chang, Yi-Ping Wang, Yu-Hsueh Wu, Yang-Che Wu, Andy Sun   +5 more
doaj   +1 more source

S-adenosylmethionine and superoxide dismutase 1 synergistically counteract Alzheimer's disease features progression in tgCRND8 mice [PDF]

, 2017
Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer's Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism ...
Cavallaro, Rosaria A, Fiorenza, Maria Teresa, Fuso, Andrea, Nicolia, Vincenzina, Scarpa, Sigfrido   +4 more
core   +2 more sources