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Ovarian Dysfunction in Peripubertal Hyperinsulinemia
Journal of the Society for Gynecologic Investigation, 2006Increasing evidence suggests that hyperinsulinemia plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS). However, the timing for the onset of hyperinsulinemia is not clear. The objective of this study was to examine the effect of peripubertal hyperinsulinemia on the maturing female reproductive axis.Hyperinsulinemia was ...
Brian T Miller, Manubai Nagamani
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