Results 111 to 120 of about 10,576 (237)

Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 1133-1138, May 2026.
Emma Bertucci, Alessandra Danieli, Francesco Ricciardiello, Isabella Neri, Francesca Monari, Alessandro D. Genazzani, Gaetano Bulfamante, Antonio La Marca, Laura Botticelli, Fabio Facchinetti, Laura Avagliano   +10 more
wiley   +1 more source

Congenital Hyperinsulinism: Diagnosis and Treatment Update

Journal of Clinical Research in Pediatric Endocrinology, 2017
Pancreatic β-cells are finely tuned to secrete insulin so that plasma glucose levels are maintained within a narrow physiological range (3.5-5.5 mmol/L).
H. Demirbilek, K. Hussain
semanticscholar   +1 more source

Acute Hyperinsulinemia during Hyperinsulinemic-Euglycemic Clamp Influences DNA Methylation and Gene Expression in Peripheral Blood Cells of Adult Men [PDF]

Diabetes & Metabolism Journal
Background Acute hyperinsulinemia may directly affect blood cells. In this study a hyperinsulinemic-euglycemic clamp (HEC) and multiomics methods were used to explore the epigenetic regulation by hyperinsulinemia in blood cells.
Minjae Joo, Dongseong Shin, Xuan Trong Truong, Seungyoon Nam, Dae Ho Lee   +4 more
doaj   +1 more source

Genotype-Phenotype associations in patients with severe hyperinsulinism of infancy

, 2007
In hyperinsulinism of infancy (HI), unregulated insulin secretion causes hypoglycemia. Pancreatectomy may be required in severe cases, most of which result from a defect in the beta-cell K-ATP channel, encoded by ABCC8 and KONJ11.
Greer, Ristan M., Jeske, Jeske, Yvette W., Cowley, David, Brown, David, Jack, Michelle M., Cotterill, Andrew M., Bowling, Francis G., Liaskou, Daphne, Walker, Rosslyn M., Thomsett, Michael J., Harris, Mark, Shah, Janaki, Bell, John R., Choong, Catherine   +13 more
core   +1 more source

Unravelling the genetic causes of mosaic islet morphology in congenital hyperinsulinism

The Journal of Pathology: Clinical Research, 2019
Congenital hyperinsulinism (CHI) causes dysregulated insulin secretion which can lead to life‐threatening hypoglycaemia if not effectively managed. CHI can be sub‐classified into three distinct groups: diffuse, focal and mosaic pancreatic disease. Whilst
J. Houghton, I. Banerjee, G. Shaikh, S. Jabbar, T. Laver, E. Cheesman, Amish Chinnoy, D. Yau, Maria Salomon Estebanez, M. Dunne, S. Flanagan   +10 more
semanticscholar   +1 more source

Anorexia nervosa versus hyperinsulinism: therapeutic effects of neuropharmacological manipulation

, 2011
Fuad Lechin1,2, Bertha van der Dijs1,2, Betty Pardey-Maldonado1, Scarlet Baez1, Marcel E Lechin31Sections of Neuroendocrinology, Neuropharmacology, and Neurochemistry, Department of Pathophysiology, Institute of Experimental Medicine, Faculty of Medicine,
Fuad Lechin, null Lechin, et al, null Pardey-Maldonado, null Baez, Betty Pardey-Maldonado, Bertha van der Dijs, B Van der Dijs   +7 more
core   +1 more source

Seizures and diagnostic difficulties in hyperinsulinism-hyperammonemia syndrome

The Turkish Journal of Pediatrics, 2016
Hyperinsulinism/hyperammonemia (HI/HA) syndrome is a rare disorder presented with recurrent hypoglycemia and elevated serum ammonia, which may lead to development delays, permanent neurologic damages, if it remains underdiagnosed.
Sibel Aka, Yasemin Alanay, Kara E Boodhansingh, Charles A Stanley, Serap Semiz   +4 more
doaj   +1 more source

Congenital Hyperinsulinism: A Novel Mutation in the KCNJ11 Gene

, 2017
Introduction Hyperinsulinism is the most common cause of both transient and persistent hypoglycemia in the neonatal period. Hyperinsulinism due to mutations in the ATP-sensitive potassium channel encoded by the KCNJ11 and ABCC8 genes cause the most ...
Flanagan, Sarah E., Bala, Keziban Asli, Demir, Nihat, Kocaman, Selami, Tuncer, Oğuz   +4 more
core  

Transient Neonatal Hypocortisolism in Neonates with Hypoglycemia – Coexistence or Cause?

Indian Journal of Endocrinology and Metabolism
Introduction: Infants born preterm, with low birth weight (LBW), or with perinatal stress are at high risk for neonatal hypoglycemia. Low cortisol levels have also been demonstrated in this group of neonates, which is often transient.
Sunetra Mondal, Lakshmi Nagendra, Amarta S. Chowdhury, Rajan Palui, Soumyadeep Biswas, Devdeep Mukherjee, Krishnendu Khan, Aritra Sengupta, Anupama Pandey   +8 more
doaj   +1 more source

Novel insights into the clinical and genomic characteristics of congenital hyperinsulinism

, 2023
Congenital hyperinsulinism is a disorder affecting the pancreatic beta cell, where insulin is inappropriately secreted during hypoglycaemia. It often appears within the first few weeks of life, and can have a severe impact on a neonate’s health and ...
TI Hewat (21935393)
core