Results 211 to 220 of about 7,125 (253)

Hyperleukocytosis and Leukostasis

2021
Patients with hematologic malignancies can develop a life-threatening hyperleukocytosis causing leukostasis, a hyperviscous state that results in decreased organ perfusion and potential complications such as disseminated intravascular coagulation, tumor lysis syndrome, and multiorgan failure. It may also be referred to as “blast crisis” as the elevated
Sharleen Yuan, Samantha J. Yarmis, Kami M. Hu   +2 more
openaire   +1 more source

Beyond the Cough: A Rare Case of Severe Pertussis With Hyperleukocytosis in a 30-day-old Malay Infant

Malaysian journal of medicine and health sciences
Pertussis infection can lead to hyperleukocytosis, characterized by a significant increase in white blood cell count. Hyperleukocytosis in pertussis is associated with disease severity and poor outcomes, particularly in young infants.
Sumaiyah Adzahar, Adibah Daud, Kamariah Abdul Jalil, Nor Rasidah Rasid, M. H. Nordin, Nabilah Rameli, Ling Pei Chi, R. H. Zulkeflee   +7 more
semanticscholar   +1 more source

Outcomes of Patients With Newly Diagnosed AML and Hyperleukocytosis

JCO Oncology Practice
PURPOSE AML presenting with hyperleukocytosis is associated with poor outcomes. We aim to understand the factors associated with early mortality and overall survival (OS) to help guide management and improve early mortality.
F. Haddad, Koiji Sasaki, J. Senapati, Lianchun Xiao, Grace S. Park, T. Abuasab, S. Venugopal, D. Rivera, A. Bazinet, R. Babakhanlou, Kunhwa Kim, F. Ong, S. Desikan, N. Pemmaraju, S. Loghavi, G. Borthakur, C. Dinardo, Hussein A. Abbas, N. Short, Naval G. Daver, E. Jabbour, G. Garcia-Manero, F. Ravandi, H. Kantarjian, T. Kadia   +24 more
semanticscholar   +1 more source

Special Clinical Scenarios: Hyperleukocytosis

2021
Acute myeloid leukemia (AML) presenting with hyperleukocytosis portends a poor diagnosis. Whether hyperleukocytosis is a sign of an inherently prognostically poor leukemia or an independent risk factor has been discussed controversially. Hyperleukocytosis indicates high tumor burden, hence tumor lysis syndrome, coagulopathy, and electrolyte disbalance ...
Gesine Bug, Halvard Bonig
openaire   +1 more source

A propensity score–matched comparison of cytoreductive strategies in patients with acute myeloid leukemia presenting with hyperleukocytosis.

Journal of Clinical Oncology
e18509 Background: Hyperleukocytosis (white blood cell (WBC) count greater than 100x109), which may lead to the clinical entity of leukostasis, is a hematologic emergency present at diagnosis in 18% of patients with acute myeloid leukemia (AML). There is
George Avetian, T. Ho, Hyun Lee, I. Bouligny, Keri R Maher   +4 more
semanticscholar   +1 more source

Therapeutic Apheresis in Hyperleukocytosis and Hyperviscosity Syndrome

Seminars in Thrombosis and Hemostasis, 2007
Therapeutic apheresis (TA), as a way of rapidly eliminating harmful or excessive blood components such as plasma proteins (plasma exchange) or cells (leukapheresis and platelet apheresis), has found broad application in a vast array of hematologic disorders.
Pierluigi Porcu
exaly   +3 more sources

CLINICAL CHALLENGES AND MANAGEMENT OF HYPERLEUKOCYTOSIS AND LEUKOSTASIS IN HEMATOLOGIC CANCERS

Global Journal For Research Analysis
Hyperleukocytosis is dened as a white blood cell (WBC) count exceeding 100,000/microL in patients with leukemia, particularly acute myeloid leukemia (AML).
Miguel Angel Díaz Díaz
semanticscholar   +1 more source

Hyperleukocytosis with pertussis.

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1997
A 9-month-old nonimmunized white female patient presented with a paroxysmal cough and a white blood cell count of 114,000/mm3. A nasopharyngeal culture was positive for Bordetella pertussis. Hyperleukocytosis is a rare complication of pertussis and is attributed to lymphocytosis-promoting factor.
V P, McCarthy, J R, Carlile
openaire   +1 more source

Hyperleukocytosis in Adult Leukemia

1985
Patients with leukemia and hyperleukocytosis are at risk of developing leukostasis [1]. Patients with acute myeloid leukemia (AML) will tend to develop symptoms of leukostasis at a white blood count (WBC) of 100000/μl. Patients with chronic myelocytic leukemia (CML) will tend to develop symptoms of leukostasis at a higher WBC of over 200000/μL Patients
Janet Cuttner, Richard Meyer, Edward P. Ambinder, Tien-Nsi Young   +3 more
openaire   +1 more source

[Pseudo-hyperkalemia and hyperleukocytosis].

Revue medicale de Bruxelles, 2013
A pseudo-hyperkalemia may occur with hyperleukocytosis. It is important to recognize it early to avoid unnecessary or even dangerous treatment inducing hypokalemia. The pseudohyperkalemia is due to cell fragility coupled to mechanical phenomena during blood collecting. We report a case of pseudo-hyperkalemia in a context of acute myeloid leukemia.
A, Goubella, A, Thooft, P, Antoine, J, Creteur, J-L, Vincent   +4 more
openaire   +1 more source