Results 21 to 30 of about 8,326 (49)

Association of apolipoprotein E with α2-macroglobulin in human plasma

Journal of Lipid Research, 1998
Apolipoprotein (apo) E plays a central role in the transport of lipids among different organs and cell types, whereas α2-macroglobulin (α2M) is responsible for the binding and inactivation of plasma proteases, as well as the transport of various ...
Larbi Krimbou, Michel Tremblay, Jean Davignon, Jeffrey S. Cohn   +3 more
doaj   +1 more source

Characterization of Common β-Thalassemia Major Mutations in Southwest Iran with Respect to Biochemical Parameters, Oxidative Status and Complications [PDF]

Journal of Advanced Biomedical Sciences, 2021
Background & Objective: Beta-thalassemia are among the most common autosomal recessive genetic disorders in Iran, especially in Khuzestan province. Beta-thalassemia exhibits significant phenotype heterogeneity and there are currently more than 200 known ...
Hamid Yaghooti, Maryam Sadat Mirlohi, Saeed Shirali, Ali Aminasnafi   +3 more
doaj  

Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is a chronic steatohepatitis disorder. If left untreated, it can progress to hepatocellular carcinoma.
Reza Afarin, Negar Dinarvand, Hossein Azizi Dariuni, Ghazal Orak, Bahar Jaberian Asl, Reza Azizi, Azam Khedri   +6 more
doaj   +1 more source

Up-regulated microRNA-185-3p inhibits the development of hyperlipidemia in rats

Kidney & Blood Pressure Research, 2022
Introduction: MicroRNA (miR)-185-3p functions in multiple cancers, while the underlying function of miR-185-3p in hyperlipidemia remained obscure. This research was conducted to unravel its function in hyperlipidemia development via modulating mastermind-
Hua Zhao, Yanbing Li
doaj   +1 more source

A new method for measurement of total plasma PCSK9: clinical applications

Journal of Lipid Research, 2010
The proprotein convertase subtilisin kexin-9 (PCSK9) circulates in plasma as mature and furin-cleaved forms. A polyclonal antibody against human PCSK9 was used to develop an ELISA that measures total plasma PCSK9 rather than only the mature form. A cross-
Geneviève Dubuc, Michel Tremblay, Guillaume Paré, Hélène Jacques, Josée Hamelin, Suzanne Benjannet, Lucie Boulet, Jacques Genest, Lise Bernier, Nabil G. Seidah, Jean Davignon   +10 more
doaj   +1 more source

Hypolipidemic effects of chitosan and its derivatives in hyperlipidemic rats induced by a high-fat diet

Food & Nutrition Research, 2016
Background: Hyperlipidemia (HLP) is the primary risk factor of cardiovascular disease (CVD). Various factors, including genetics, physical inactivity, and daily nutritional habits, affect the prevalence of HLP.
Haitao Pan, Qingyun Yang, Guidong Huang, Chen Ding, Peiqiu Cao, Lanlan Huang, Tiancun Xiao, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Anti-Obese Effect of Glucosamine and Chitosan Oligosaccharide in High-Fat Diet-Induced Obese Rats

Marine Drugs, 2015
Objective: This study is to evaluate the anti-obese effects of glucosamine (GLC) and chitosan oligosaccharide (COS) on high-fat diet-induced obese rats. Methods: The rats were randomly divided into twelve groups: a normal diet group (NF), a high-fat diet
Lanlan Huang, Jian Chen, Peiqiu Cao, Haitao Pan, Chen Ding, Tiancun Xiao, Pengfei Zhang, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Impact of Gut Microbiota and Microbiota-Related Metabolites on Hyperlipidemia

Frontiers in Cellular and Infection Microbiology, 2021
Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been considered as a high-risk factor and key indicator of many metabolic diseases.
Xiaokang Jia, Xiaokang Jia, Xiaokang Jia, Wen Xu, Wen Xu, Lei Zhang, Xiaoyan Li, Xiaoyan Li, Ruirui Wang, Shuisheng Wu, Shuisheng Wu   +10 more
doaj   +1 more source

Remnant-like particle cholesterol and triglyceride levels of hypertriglyceridemic patients in the fed and fasted state

Journal of Lipid Research, 2000
Potentially atherogenic triglyceride-rich lipoprotein (TRL) remnants can be isolated and quantitated as remnant-like particles (RLP), using an immunoaffinity gel containing specific anti-human apolipoprotein A-I (apoA-I) and apoB-100 monoclonal ...
Caroline Marcoux, Paul N. Hopkins, Tao Wang, Elizabeth Teng Leary, Katsuyuki Nakajima, Jean Davignon, Jeffrey S. Cohn   +6 more
doaj   +1 more source

A cross-sectional study exploring the relationship between the dietary inflammatory index and hyperlipidemia based on the National Health and Nutrition Examination Survey (2005–2018)

Lipids in Health and Disease, 2023
Background Hyperlipidemia is closely associated with dietary patterns and inflammation. However, the relationship between hyperlipidemia and the inflammatory potential of diets remains unexplored.
Yu Han, Xijuan Jiang, Yabin Qin, Yile Zhao, Guying Zhang, Chao Liu   +5 more
doaj   +1 more source