Results 31 to 40 of about 8,326 (49)

Effect of atorvastatin on plasma apoE metabolism in patients with combined hyperlipidemia

Journal of Lipid Research, 2002
Atorvastatin, a synthetic HMG-CoA reductase inhibitor used for the treatment of hyperlipidemia and the prevention of coronary artery disease, significantly lowers plasma cholesterol and low-density lipoprotein cholesterol (LDL-C) levels.
Jeffrey S. Cohn, Michel Tremblay, Rami Batal, Hélène Jacques, Lyne Veilleux, Claudia Rodriguez, P.Hugh R. Barrett, Denise Dubreuil, Madeleine Roy, Lise Bernier, Orval Mamer, Jean Davignon   +11 more
doaj   +1 more source

Hyperlipidemia and mortality associated with diabetes mellitus co-existence in Chinese peritoneal dialysis patients

Lipids in Health and Disease, 2020
Background To evaluate associations between diabetes mellitus (DM) coexisting with hyperlipidemia and mortality in peritoneal dialysis (PD) patients. Methods This was a retrospective cohort study with 2939 incident PD patients in China from January 2005 ...
Xin Wei, Yueqiang Wen, Qian Zhou, Xiaoran Feng, Fen Fen Peng, Niansong Wang, Xiaoyang Wang, Xianfeng Wu   +7 more
doaj   +1 more source

Association between serum Klotho concentration and hyperlipidemia in adults: a cross-sectional study from NHANES 2007–2016

Frontiers in Endocrinology, 2023
ObjectiveThe Klotho protein is a well-documented anti-aging protein known for its diverse biological functions. Hyperlipidemia is an established independent risk factor for various chronic diseases.
Shaohua Yan, Wei Luo, Li Lei, Qiuxia Zhang, Jiancheng Xiu   +4 more
doaj   +1 more source

Overexpression of apoC-I in apoE-null mice

Journal of Lipid Research, 2002
Apolipoprotein C-I (apoC22222222246) has been proposed to act primarily via interference with apoE-mediated lipoprotein uptake. To define actions of apoC-I that are independent of apoE, we crossed a moderately overexpressing human apoC-I transgenic ...
Karin Conde-Knape, André Bensadoun, Joan H. Sobel, Jeffrey S. Cohn, Neil S. Shachter   +4 more
doaj   +1 more source

Atorvastatin’s Therapeutic Potential in Atherosclerosis: Inhibiting TGF-β-Induced Proteoglycan Glycosaminoglycan Chain Elongation through ROS-ERK1/2-Smad2L Signaling Pathway Modulation in Vascular Smooth Muscle Cells [PDF]

Cell Journal
Objective: According to the response-to-retention hypothesis, the inception of atherosclerosis is attributed to thedeposition and retention of lipoprotein in the arterial intima, facilitated by altered proteoglycans with hyperelongatedglycosaminoglycan ...
Hossein Ghaderi-Zefrehi, Ghorban Mohammadzadeh, Mojtaba Rashidi, Maryam Adelipour, Hossein Babaahmadi Rezaei   +4 more
doaj   +1 more source

Beneficial effects of cranberry juice enriched with omega-3 fatty acids in patients with type 2 diabetic and periodontal disease: A randomized pilot clinical trial [PDF]

Journal of Advanced Periodontology and Implant Dentistry
Background. The present study evaluated the effects of cranberry juice enriched with omega-3 on inflammatory, oxidative stress, and periodontal status in diabetic patients with periodontal disease. Methods.
Elnaz Ashrafzadeh, Hossein Babaei, Maryam Ravanbakhsh, Ahmad Zare Javid, Leila Maghsoumi-Norouzabad   +4 more
doaj   +1 more source

Statin use and the risk of chronic kidney disease in patients with psoriasis: A nationwide cohort study in Taiwan.

PLoS ONE, 2020
BackgroundPsoriasis is associated with hyperlipidemia. Few studies have examined the association among psoriasis, hyperlipidemia, and chronic kidney disease (CKD).
Kwei-Lan Liu, Wen-Chien Tsai, Hung-Pin Tu, Chih-Hung Lee   +3 more
doaj   +1 more source

Metabonomics study of the therapeutic mechanism of Gynostemma pentaphyllum and atorvastatin for hyperlipidemia in rats. [PDF]

PLoS ONE, 2013
Gynostemma pentaphyllum (GP) is widely used for the treatment of diseases such as hyperlipidemia, fatty liver and obesity in China, and atorvastatin is broadly used as an anti-hyperlipidemia drug. This research focuses on the plasma and liver metabolites
Miao Wang, Fei Wang, Yinan Wang, Xiaonan Ma, Min Zhao, Chunjie Zhao   +5 more
doaj   +1 more source

Elevated Interleukin-38 Level Associates with Clinical Response to Atorvastatin in Patients with Hyperlipidemia

Cellular Physiology and Biochemistry, 2018
Background/Aims: Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. And it is tightly related to chronic inflammation. Interleukin-38 (IL-38) represents a new member of anti-inflammatory cytokines.
Ning Yang, Yanqiu Song, Bo Dong, Yang Li, Lu Kou, Jingyu Yang, Qin Qin   +6 more
doaj   +1 more source

Alterations of Gut Microbiota and Blood Lipidome in Gestational Diabetes Mellitus With Hyperlipidemia

Frontiers in Physiology, 2019
Clinical gestational diabetes mellitus (GDM) is frequently associated with hyperlipidemia comorbidity. Altered human gut microbiome has been linked to GDM and hyperlipidemia, respectively but not the comorbid condition. We hypothesize that the occurrence
He Liu, He Liu, Li-Long Pan, Siting Lv, Qin Yang, Hao Zhang, Hao Zhang, Wei Chen, Wei Chen, Zhuwu Lv, Jia Sun, Jia Sun   +11 more
doaj   +1 more source