Results 61 to 70 of about 6,540 (205)

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell, Ahlberg, Balasubramaniam, Barlett, Bernd Seifferth, Berr, Berr, Berr, Berr, Carey, Carey, Carulli, Cohen, Cohen, Coleman, Dam, Delchier, Dieter Jüngst, Everson, Frieder Berr, Glenn, Goodnight, Gustav Paumgartner, Harris, Hofmann, Holan, Holzbach, Joseph Holl, Juniper, Kaludzny, Kelly, Kuroki, Leaf, Lee, Lippel, Lorenz, Magnuson, Marks, Nestel, Nestel, O'Leary, Parhofer, Paul, Phillipson, Pomeranz, Ramond, Robins, Robins, Sanders, Scobey, Sedaghat, Snedecor, Strasberg, Sven Fischer, Sömjen, Ventura, von Schacky, Wagner, Wechsler, Werner O. Richter   +59 more
core   +1 more source

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi, Benneth Ben‐Azu, Ejayeta Jeroh, Faith B. Friday   +3 more
wiley   +1 more source

Facilitators, barriers, and insights using an HFA‐PEFF‐based clinical decision support system: A proof‐of‐concept study

ESC Heart Failure, Volume 12, Issue 5, Page 3655-3666, October 2025.
Analysis of the usage of the HFA‐PEFF score‐based clinical decision support system (CDSS) and the main barriers and facilitators to its implementation, based on a survey of physicians. Abstract Background and aims Knowing that heart failure (HF) with preserved ejection fraction (HFpEF) can be difficult to diagnose, a clinical decision support system ...
Isidora Milosavljević, Ivan Petrović, Aleksandra Ilić, Dragana Dabović, Aleksandra Milovančev, Goran Remer, Vladimir Vuković, Dimitrije Zdravković, Maja Stefanović, Snežana Stojšić, Ana Balenović, Goran Lončar, Snežana Tadić, Milana Jaraković, Snežana Bjelić, Snežana Čemerlić, Marija Bjelobrk, Tatjana Miljković, Andrej Preveden, Milovan Petrović, Srdjan Maletin, Tanja Popov, Vanja Drljević Todić, Mirko Todić, Aleksandra Vulin, Milenko Čanković, Dragica Andrić, Dragoslava Živkov Šaponja, Aleksandar Redžek, Anastazija Stojšić Milosavljević   +29 more
wiley   +1 more source

Protective mechanisms against Alzheimer's disease in APOE3‐Christchurch homozygous astrocytes

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by tau pathology, leading to neurodegeneration. Astrocytes regulate central nervous system homeostasis and influence AD progression. The APOE3‐Christchurch (APOE3‐Ch) variant is linked to AD resilience, but its protective mechanisms remain unclear.
Xinran Tian, Erica Keane Rivera, Inyoung Hwang, Arina A. Nikitina, Jennifer A. Smith, Youngsuh J. Cho, Julia Sala‐Jarque, Austin DuBose, Clare Andriola, Toby Gollan‐Myers, Kenneth S. Kosik   +10 more
wiley   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, Volume 89, Issue 4, Page 208-227, July 2025.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Clinical features, biomarker profiles, and neuroimaging characteristics in patients from memory clinic in china: The Shanghai Memory Study

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Despite advances in biomarker assessment, molecular neuroimaging, and disease‐modifying therapies for cognitive disorders, China lacks well‐characterized clinical cohorts integrating comprehensive clinical assessments and multimodal biomarkers.
Jie Wang, Xiaoxi Ma, Jiaying Lu, Jie Wu, Zhenxu Xiao, Huiwei Zhang, Weiqi Bao, Saineng Ding, Li Zheng, Xiaoniu Liang, Yihui Guan, Chuantao Zuo, Ding Ding, Qianhua Zhao, the Shanghai Memory Study (SMS)   +14 more
wiley   +1 more source

Association of Cardiovascular Biomarkers With Cardiac Allograft Vasculopathy and Atherosclerotic Coronary Artery Disease

Clinical Transplantation, Volume 39, Issue 6, June 2025.
ABSTRACT Background: Cardiac allograft vasculopathy (CAV) remains a barrier to long‐term survival after heart transplantation. Little is known about cardiovascular biomarkers in CAV and how they compare to biomarkers in atherosclerotic coronary artery disease (CAD).
Lukas Köster, Jessica Weimann, Alexander Bernhard, Benjamin Bay, Christopher M. Blaum, Thiess Lorenz, Tanja Zeller, Christoph Waldeyer, Hermann Reichenspurner, Paulus Kirchhof, Stefan Blankenberg, Christina Magnussen, Fabian J. Brunner   +12 more
wiley   +1 more source

Yellow palms and feet in a child

Russian Open Medical Journal, 2014
The yellowish discoloration of the palms and skin is reported under different terms: xanthodermia, hypercarotenemia, carotenemia, carotenodermia. Yellow discoloration of the skin may be associated with carotenemia, hypothyroidism, diabetes mellitus ...
Anca Chiriac, Anca E. Chiriac, Tudor Pinteala, Elena Gologan, Caius Solovan, Piotr Brzezinski   +5 more
doaj  

A Cross-Sectional Study of Prisoners in Mexico City Comparing Prevalence of Transmissible Infections and Chronic Diseases with That in the General Population. [PDF]

, 2015
ObjectivesTo describe patterns of transmissible infections, chronic illnesses, socio-demographic characteristics and risk behaviors in Mexico City prisons, including in comparison to the general population, to identify those currently needing healthcare ...
Bautista-Arredondo, Sergio, Bertozzi, Stefano M, Beynon, Fenella, Conde-Glez, Carlos J, González, Andrea, Gras, Nathalie, Juarez-Figueroa, Luis, Lopez-Ridaura, Ruy, Servan-Mori, Edson, Sierra-Madero, Juan, Volkow, Patricia   +10 more
core   +3 more sources

Human macrophage pro‐inflammatory polarization in response to free cholesterol and cholesterol remnants

Physiological Reports, Volume 13, Issue 10, May 2025.
Abstract Atherosclerosis is a chronic inflammatory disease of the blood vessels caused by elevated levels of lipoproteins. The hyperlipoproteinemia triggers a series of cellular changes, particularly the activation of the macrophages, which play a crucial role in the development and progression of atherosclerosis.
Karel Paukner, Barbora Muffova, Hana Bartuskova, Jan Mareš, Libor Janousek, Jiri Fronek, Sona Kauerova, Ivana Kralova Lesna, Rudolf Poledne   +8 more
wiley   +1 more source