Results 11 to 20 of about 4,332 (175)

Primary hyperoxaluria in infants

Saudi Journal of Kidney Diseases and Transplantation, 2016
The infantile form of primary hyperoxaluria type-1 (PH-1) is characterized by a rapid progression to the end-stage renal disease (ESRD) due to both increased oxalate load and reduced glomerular filtration rate.
Manel Jellouli, Mariem Ferjani, Kamel Abidi, Chokri Zarrouk, Ouns Naija, J Abdelmoula, Tahar Gargah   +6 more
doaj   +3 more sources

Probiotics and Their Functional Role in Mitigating Antinutrient Effects In Vivo-A Systematic Review and Meta-Analysis. [PDF]

Compr Rev Food Sci Food Saf
ABSTRACT Antinutrients like phytic acid and oxalates reduce mineral bioavailability by forming insoluble complexes with iron, zinc, and calcium. Probiotic supplementation may counteract these effects through enzymatic activity (e.g., phytase, oxalate decarboxylase) and microbiota modulation. This PRISMA‐based meta‐analysis evaluated 27 in vivo studies (
Olar-Pop L, Cornea-Cipcigan M, Ciont CC, Suharoschi R, Pop RM, Pop OL.   +5 more
europepmc   +2 more sources

The Primary Hyperoxalurias [PDF]

Journal of the American Society of Nephrology, 2001
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
M, Marangella, M, Petrarulo, C, Vitale, C, Bagnis, S, Berutti, A, Ramello, A, Amoroso   +6 more
openaire   +4 more sources

Primary Hyperoxaluria [PDF]

Clinical Journal of the American Society of Nephrology, 2020
Living with primary hyperoxaluria—a rare genetic disease with excess oxalate production leading to frequent kidney stones, kidney impairment, and oxalosis—presents many challenges to patients, caregivers, and their families.
Jennifer E, Lawrence, Debra J, Wattenberg   +1 more
openaire   +4 more sources

The primary hyperoxalurias [PDF]

Kidney International, 2009
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Hoppe, Bernd, Beck, Bodo B., Milliner, Dawn S.   +2 more
openaire   +2 more sources

Isolated Kidney Transplant in Primary Hyperoxaluria-1 Enabled by Small Interfering RNA (siRNA) Therapy. Is It Time for Change? Case Report and Review of the Literature. [PDF]

Pediatr Transplant
ABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by excessive oxalate production that leads to nephrocalcinosis or nephrolithiasis and progressive kidney failure, associated with systemic oxalosis that is not reversed by dialysis. Pharmacological treatment is limited.
Habeeb SM, Simkova E, Al-Akash S, Awad HS, Yamin H, Eid LA, Aldhaheri WS, Concepcion W, Bitzan M.   +8 more
europepmc   +2 more sources

Unusual cause of renal failure in infancy: Primary hyperoxaluria

Journal of Pediatric Critical Care, 2015
Background: Primary hyperoxaluria is a rare disease characterized by the excessive production and accumulation of oxalate in the body. Methods: We described the case of an infant with primary hyperoxaluria type who had end-stage renal failure in the ...
Kanchan Channawar, V S V Prasad
doaj   +1 more source

Treatment of Primary Hyperoxaluria [PDF]

Archives of Disease in Childhood, 1970
Abstract Nine patients with primary hyperoxaluria have been followed regularly for 1 to 11 years, and their treatment and progress are discussed in relation to the known natural history of the disease. 6 of them probably have the usual form of primary hyperoxaluria associated with increased glycollic acid excretion, while 3 who are sibs have the ...
C E, Dent, T C, Stamp
openaire   +2 more sources

Anemia in patient with primary hyperoxaluria and bone marrow involvement by oxalate crystals

Hematology/Oncology and Stem Cell Therapy, 2018
We present a rare case of anaemia secondary to bone marrow infiltration by oxalate crystals and renal failure in a patient diagnosed with primary hyperoxaluria. In our case, the anaemia was recovered after the double liver and kidney transplantation, the
Vitaliy Mykytiv, Fiz Campoy Garcia
doaj   +1 more source

Multidisciplinary Cooperation in a Simultaneous Combined Liver and Kidney Transplantation Patient of Primary Hyperoxaluria

Journal of Nepal Medical Association, 2017
Primary hyperoxaluria type 1 is an autosomal recessive hereditary glyoxylate metabolism disorder characterized by excessive production of oxalate, caused by the deficiency of liver specific peroxisomal enzyme: alanineglyoxylate aminotransferase.
Ren Qingqi, Ju Weiqiang, Wang Dongping, Guo Zhiyong, Chen Maogen, He Xiaoshun   +5 more
doaj   +1 more source