Results 21 to 30 of about 5,205 (214)

Purslane-induced oxalate nephropathy: case report and literature review

BMC Nephrology, 2023
Background The kidney is particularly vulnerable to toxins due to its abundant blood supply, active tubular reabsorption, and medullary interstitial concentration.
Xiangtuo Wang, Xiaoyan Zhang, Liyuan Wang, Ruiying Zhang, Yingxuan Zhang, Lei Cao   +5 more
doaj   +1 more source

The primary hyperoxalurias [PDF]

Kidney International, 2009
The primary hyperoxalurias (PHs) are rare disorders of glyoxylate metabolism in which specific hepatic enzyme deficiencies result in overproduction of oxalate. Due to the resulting severe hyperoxaluria, recurrent urolithiasis or progressive nephrocalcinosis are principal manifestations.
Hoppe, Bernd, Beck, Bodo B., Milliner, Dawn S.   +2 more
openaire   +2 more sources

Primary hyperoxaluria: the pediatric nephrologist's point of view

, 2022
The clinical presentation of primary hyperoxaluria in children ranges from mildly symptomatic nephrocalcinosis to very early onset end-stage kidney failure with systemic oxalosis, a devastating complication.
Garrelfs, Sander F, Groothoff, Jaap W, Ben-Shalom, Efrat, Groothoff, Jaap W., Garrelfs, Sander F.   +4 more
core   +1 more source

Compliance in patients with dietary hyperoxaluria: A cohort study and systematic review

Asian Journal of Urology, 2019
Objective: Hyperoxaluria leads to calcium oxalate crystal formation and subsequent urolithiasis. This study aims to analyse the effect of treatment compliance in hyperoxaluria, firstly by analysis of patients with non-primary hyperoxaluria and secondly ...
Derek B. Hennessey, Ned Kinnear, Gilbert Rice, David Curry, Siobhan Woolsey, Brian Duggan   +5 more
doaj   +1 more source

Unusual cause of renal failure in infancy: Primary hyperoxaluria

Journal of Pediatric Critical Care, 2015
Background: Primary hyperoxaluria is a rare disease characterized by the excessive production and accumulation of oxalate in the body. Methods: We described the case of an infant with primary hyperoxaluria type who had end-stage renal failure in the ...
Kanchan Channawar, V S V Prasad
doaj   +1 more source

Treatment of Primary Hyperoxaluria [PDF]

Archives of Disease in Childhood, 1970
Abstract Nine patients with primary hyperoxaluria have been followed regularly for 1 to 11 years, and their treatment and progress are discussed in relation to the known natural history of the disease. 6 of them probably have the usual form of primary hyperoxaluria associated with increased glycollic acid excretion, while 3 who are sibs have the ...
C E, Dent, T C, Stamp
openaire   +2 more sources

End Points for Clinical Trials in Primary Hyperoxaluria

, 2020
Patients with primary hyperoxaluria experience kidney stones from a young age and can develop progressive oxalate nephropathy. Progression to kidney failure often develops over a number of years, and is associated with systemic oxalosis, intensive ...
Milliner, Dawn S., Dehmel, Bastian, John Knight, Melanie Blank, Blank, Melanie, Jaap Groothoff, Knight, John, Sonia Fargue, W. Todd Lowther, Sixun Yang, West, Melissa, Lieske, John C., Dawn S. Milliner, Tracy L. McGregor, Ralf Rosskamp, Yang, Sixun, Fargue, Sonia, Thompson, Aliza, Lowther, W. Todd, Kim Hollander, Groothoff, Jaap, Rosskamp, Ralf, Aliza Thompson, Bastian Dehmel, Hollander, Kim, Meaghan Allain, Rumsby, Gill, McGregor, Tracy L., Allain, Meaghan, Gill Rumsby, John C. Lieske, Melissa West   +31 more
core   +1 more source

Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1

, 2021
Background and objectives In the rare disease primary hyperoxaluria type 1, overproduction of oxalate by the liver causes kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis.
Jaap W. Groothoff, GROOTHOFF, Jaap W., HARAMBAT, Jerome, DESCHENES, Georges, HULTON, Sally-Anne, van’t Hoff, William G., David V. Erbe, LORCH, Ulrike, Akshay K. Vaishnaw, Ulrike Lorch, HASLETT, Patrick, GARG, Pushkal P., Pushkal P. Garg, William G. van’t Hoff, VAISHNAW, Akshay K., Dawn S. Milliner, Tracy L. McGregor, Pierre Cochat, MAGEN, Daniella, TALAMUDUPULA, Sandeep, Patrick Haslett, LIESKE, John C., Yaacov Frishberg, Sally-Anne Hulton, MCGREGOR, Tracy L., Jérôme Harambat, Bahru A. Habtemariam, COCHAT, Pierre, MILLINER, Dawn S., LU, Jiandong, Georges Deschênes, ERBE, David V., HABTEMARIAM, Bahru A., STUDY, Collaborators, Jiandong Lu, Daniella Magen, John C. Lieske, VAN'T HOFF, William G., Sandeep Talamudupula, FRISHBERG, Yaacov   +39 more
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Anemia in patient with primary hyperoxaluria and bone marrow involvement by oxalate crystals

Hematology/Oncology and Stem Cell Therapy, 2018
We present a rare case of anaemia secondary to bone marrow infiltration by oxalate crystals and renal failure in a patient diagnosed with primary hyperoxaluria. In our case, the anaemia was recovered after the double liver and kidney transplantation, the
Vitaliy Mykytiv, Fiz Campoy Garcia
doaj   +1 more source

The Struggling Odyssey of Infantile Primary Hyperoxaluria

Frontiers in Pediatrics, 2021
Introduction: Oxalate overproduction in Primary Hyperoxaluria type I (PH1) leads to progressive renal failure and systemic oxalate deposition. In severe infantile forms of PH1 (IPH1), end-stage renal disease (ESRD) occurs in the first years of life ...
Adrien Guillaume, Adrien Guillaume, Benedetta Chiodini, Brigitte Adams, Karin Dahan, Georges Deschênes, Khalid Ismaili   +6 more
doaj   +1 more source