Results 71 to 80 of about 9,955 (227)

Does instrumentation and irrigation configuration affect intrarenal pressure during PCNL?

open access: yesBJUI Compass, Volume 7, Issue 2, February 2026.
Abstract Objectives To measure the effects of varying configurations of nephroscope sheath, irrigation, instruments, and suction on intrarenal pressure (IRP) during percutaneous nephrolithotomy (PCNL). Materials and Methods Kidney and ureter 3D printed models from a deidentified patient's CT scan were placed in a plaster and foam mould, simulating the ...
Evan Seibly   +15 more
wiley   +1 more source

The intestine and the kidneys : a bad marriage can be hazardous [PDF]

open access: yes, 2015
The concept that the intestine and chronic kidney disease influence each other, emerged only recently. The problem is multifaceted and bidirectional. On one hand, the composition of the intestinal microbiota impacts uraemic retention solute production ...
Glorieux, Griet, Vanholder, Raymond
core   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO2.
Abhishek Albert   +9 more
doaj   +1 more source

Calcium oxalate crystal adherence to hyaluronan-, osteopontin-, and CD44-expressing injured/regenerating tubular epithelial cells in rat kidneys [PDF]

open access: yes, 2003
Retention of crystals in the kidney is an essential early step in renal stone formation. Studies with renal tubular cells in culture indicate that hyaluronan (HA) and osteopontin (OPN) and their mutual cell surface receptor CD44 play an
Asselman, M. (Marino)   +3 more
core   +2 more sources

Computerized tomography‐derived body composition metrics are associated with 24‐h urine lithogenic parameters

open access: yesBJUI Compass, Volume 7, Issue 1, January 2026.
Abstract Background The relationship between body composition and lithogenic urine parameters remains poorly defined. This study aimed to evaluate associations between computerized tomography (CT)‐derived body composition metrics and 24‐h urine findings. Methods Stone‐forming patients in our Nephrolithiasis Database who underwent 24‐h urine testing and
Reza Lahiji   +14 more
wiley   +1 more source

Nephroprotective Effect of Pleurotus ostreatus and Agaricus bisporus Extracts and Carvedilol on Ethylene Glycol-Induced Urolithiasis: Roles of NF-κB, p53, Bcl-2, Bax and Bak

open access: yesBiomolecules, 2020
This study was designed to assess the nephroprotective effects of Pleurotus ostreatus and Agaricus bisporus aqueous extracts and carvedilol on hyperoxaluria-induced urolithiasis and to scrutinize the possible roles of NF-κB, p53, Bcl-2, Bax and Bak ...
Osama M. Ahmed   +4 more
doaj   +1 more source

Microscopic Haematuria [PDF]

open access: yes, 2005
A 30 year old man is referred for a medical check up before taking a life insurance policy. He is asymptomatic, gives no relevant history, is on no treatment and physical examination is unremarkable. Routine dip-stick analysis of a mid­stream specimen of
Vella, Mario P.
core  

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi   +3 more
wiley   +1 more source

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