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Hyperoxia and lung disease

Current Opinion in Pulmonary Medicine, 1998
Experimental studies and few human reports demonstrate that hyperoxia increases the level of reactive oxygen-derived free radicals and that these substances can produce oxidative cellular injury. However, available data suggest that the human lung is more resistant to hyperoxic oxidative damage than previously expected and demonstrate that absorption ...
C R, Carvalho   +3 more
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Hyperoxia and Lung Metabolism

Chest, 1974
N umerous studies have been conducted on the pathologic changes that occur in the lung due to exposure to hyperbaric oxygen. These studies indicate that the entire lung, from the epithelium of the upper respiratory tract down to the pulmonary capillary endothelium, can be damaged by prolonged exposure to elevated partial pressures of oxygen.' Reports ...
W D, Currie, P C, Pratt, A P, Sanders
openaire   +2 more sources

Pathways of cell signaling in hyperoxia

Free Radical Biology and Medicine, 2003
Administration of high concentrations of oxygen (hyperoxia) is a mainstay of supportive treatment for patients suffering from severe respiratory failure. However, hyperoxia, by generating excess systemic reactive oxygen species (ROS), can exacerbate organ failure by causing cellular injury.
Patty J Lee
exaly   +3 more sources

Response of choroidal blood flow in the foveal region to hyperoxia and hyperoxia-hypercapnia

Current Eye Research, 2000
Arterial carbon dioxide tension and arterial oxygen tension are important determinants of retinal and cerebral blood flow. In the present study the hypothesis that changes in arterial blood gases also influence choroidal blood flow was tested.The effect of breathing different mixtures of oxygen (O(2)) and carbon dioxide (CO(2)) on choroidal blood flow ...
M H, Geiser   +5 more
openaire   +2 more sources

Effects of hyperoxia on phagocytosis

Blut, 1982
The development of bacterial infections is a common complication during treatment with high concentrations of oxygen. To study the effect of hyperoxia on phagocytes, the adherence, chemotaxis, ingestion rates, degranulation as well as the bactericidal activity were measured in alveolar macrophages (AMs) and polymorphonuclear leukocytes (PMNs) obtained ...
openaire   +2 more sources

Hyperoxia in head injury

Current Opinion in Critical Care, 2004
Currently, no neuroprotective therapies have been shown to reduce the secondary neuronal damage occurring after traumatic brain injury. Recent studies have addressed the potentiality of hyperoxia to ameliorate brain metabolism after traumatic brain injury.
L.G. Longhi, N. Stocchetti
openaire   +3 more sources

Diaphragmatic fatigue in normoxia and hyperoxia

Journal of Applied Physiology, 1985
Diaphragmatic fatigue was induced in six normal young men inspiring against a variable alinear resistance. Breathing pattern was rigidly controlled (tidal volume 0.75 liter, 12 breaths . min-1). Fatigue was defined as an inability to continue to generate a target transdiaphragmatic pressure (Pdi = 0.65 - 0.84 Pdimax). Diaphragmatic electromyogram (EMG,
R L, Pardy, P T, Bye
openaire   +2 more sources

Hyperoxia and Functional MRI

2016
Oxygen plays a fundamental role in functional magnetic resonance imaging (FMRI). Blood oxygenation level-dependent (BOLD) imaging is the foundation stone of all FMRI and is still the essential workhorse of the vast majority of FMRI procedures. Hemoglobin may provide the magnetic properties that allow the technique to work, but it is oxygen that allows ...
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Hyperoxia

Journal of Neurosurgery, 2007
Gaylan L, Rockswold, Sarah B, Rockswold
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Hypoxia and hyperoxia

The American Journal of Surgery, 1957
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