Results 1 to 10 of about 69,096 (237)
Hyperparathyroidism is a common disorder characterized by excessive secretion of parathyroid hormone (PTH) and resultant hypercalcemia. Primary hyperparathyroidism typically occurs in the setting of hypercellular growth of one or more parathyroid glands, associated with dysregulation of PTH release.
Andrew Arnold, Jessica Costa-Guda
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European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz+3 more
wiley +1 more source
Familial Hyperparathyroidism [PDF]
Regulation of the serum calcium level in humans is achieved by the endocrine action of parathyroid glands working in concert with vitamin D and a set of critical target cells and tissues including osteoblasts, osteoclasts, the renal tubules, and the small intestine.
Jenny E. Blau+2 more
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This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek+18 more
wiley +1 more source
Abstract All the reported cases present many or all of the clinical features characteristic of hyperparathyroidism, and in all of those in which surgical or postmortem exploration of the neck was performed definite tumors of one or more parathyroid glands were found.
J.E. Jacobs, J.Dewey Bisgard
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Louw, J.H., Joffe, S.N.
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Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi+5 more
wiley +1 more source
Primary hyperparathyroidism [PDF]
Key Clinical MessageWe report a case of hyperparathyroidism with hypercalcemia caused by a giant parathyroid adenoma. We use a technetium sestamibi scan to locate parathyroid mass. Bone emission computed tomography revealed the classic signs of metabolic osteopathy. She was recovered after parathyroidectomy.
Ao Wang, Lei Yuan
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Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé+5 more
wiley +1 more source
An Update: Enzymatic Synthesis for Industrial Applications
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer+4 more
wiley +1 more source