Results 41 to 50 of about 73,755 (243)

Comparison of first- and second-line imaging diagnostics (ultrasound + scintigraphy and PET + 4DCT) in visualizing parathyroid glands in primary hyperparathyroidism including ectopic foci

Journal of Education, Health and Sport
Introduction: Primary hyperparathyroidism is an endocrine disorder that causes disturbances in calcium and phosphorus metabolism in the human body.
Laura Loryś, Klaudia Klimczak, Kamila Budzyńska, Marcin Narloch, Stanisław Kasprzak, Karolina Kasprzak, Jakub Kamiński, Norbert Kandefer   +7 more
doaj   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis

Arthritis &Rheumatology, EarlyView.
Objective Transition from long‐term denosumab (Dmab) to parathyroid hormone‐analogs or romosozumab (Romo) might expose patients to the risk of the so‐called rebound phenomenon. Adding Romo to Dmab might represent an option in patients experiencing a fracture while on Dmab.
Giovanni Adami, Francesco Pollastri, Angelo Fassio, Filippo Montanari, Anna Piccinelli, Camilla Benini, Emma Pasetto, Carmen Dartizio, Davide Gatti, Maurizio Rossini, Ombretta Viapiana   +10 more
wiley   +1 more source

Unmasking of normocalcemic primary hyperparathyroidism after sodium-glucose cotransporter-2 inhibitor initiation

European Journal of Case Reports in Internal Medicine
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have complex interactions with bone metabolism, including an increase in parathyroid hormone (PTH) levels.
Christodoulos Dolapsakis, Emmanouil Karofylakis, Stamatios Chalvatzis   +2 more
doaj   +1 more source

Mandibular Osteitis Fibrosa Cystica as First Sign of Vitamin D Deficiency

Case Reports in Dentistry, 2018
Introduction. Brown tumors of hyperparathyroidism are locally destructive bone lesions. They are the late clinical consequence of the disease. They can occur in primary, secondary, and rarely tertiary forms.
Nour Mellouli, Raouaa Belkacem Chebil, Marwa Darej, Yosra Hasni, Lamia Oualha, Nabiha Douki   +5 more
doaj   +1 more source

Parathyroid adenoma: multimodal diagnosis capabilities: A retrospective study

Consilium Medicum, 2023
Background. Primary hyperparathyroidism is a common endocrinological disease caused mainly by parathyroid adenoma. The main treatment method is surgery (parathyroidectomy). Therefore, the exact determination of adenoma localization is crucial. Aim. To
Nikolai A. Ognerubov, Tatiana S. Antipova, Galina N. Abakumova   +2 more
doaj   +1 more source

Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]

, 2020
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (FIHP)
Christie, Paul T., Javid, Mahsa, Kooblall, Kreepa G., Lines, Kate E., Mallon, Ann-Marie, Newey, Paul J., Piret, Sian E., Reed, Anita Ac, Simon, Michelle, Stevenson, Mark, Thakker, Rajesh V., Walls, Gerard V.   +11 more
core   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Long-term therapeutic outcomes of papillary thyroid carcinoma with concomitant hyperparathyroidism: A single center case-control study

Biomedical Journal, 2020
Background: Papillary thyroid carcinoma occasionally presents with concomitant hyperparathyroidism; however, the clinical significance has not been well established.
Chih-Yiu Tsai, Szu-Tah Chen, Chuen Hsueh, Yann-Sheng Lin, Jen-Der Lin   +4 more
doaj   +1 more source

Localization Strategy Prior to Radiofrequency Ablation for Primary and Secondary Hyperparathyroidism

Biomedicines, 2023
Objective: Preoperative localization in patients with primary or secondary hyperparathyroidism before radiofrequency ablation (RFA) is crucial. There is currently a lack of consensus regarding imaging protocol.
Chih-Ying Lee, Yen-Hsiang Chang, Pi-Ling Chiang, Cheng-Kang Wang, An-Ni Lin, Chi-Cheng Chen, Yi-Fan Chen, Shun-Yu Chi, Fong-Fu Chou, Wei-Che Lin   +9 more
doaj   +1 more source