Results 131 to 140 of about 26,081 (268)

Improving the diagnosis of hyperphagia in melanocortin‐4 receptor pathway diseases [PDF]

open access: yes
Characteristics of hyperphagia include heightened and prolonged hunger, longer time to satiation, shorter duration of satiety, severe preoccupation with food (i.e., hyperphagic drive), abnormal food-seeking behaviors, and distress or functional ...
Haqq, Andrea   +14 more
core   +1 more source

Food deprivation and compensatory growth in juvenile piava, Leporinus obtusidens

open access: yesBoletim do Instituto de Pesca, 2018
The growth and body composition of Leporinus obtusidens juveniles (32.0 ± 8.0 g; 137.3 ± 11.9 mm) were evaluated under food deprivation followed by refeeding.
Alex Pires de Oliveira NUÑER   +1 more
doaj  

Quality of life improvements with setmelanotide treatment in acquired hypothalamic obesity: TRANSCEND trial interview results from US participants

open access: yesFrontiers in Behavioral Neuroscience
IntroductionAcquired hypothalamic obesity (HO), caused by hypothalamic injury, is characterized by hyperphagia (i.e., insatiable hunger and abnormal food-seeking behaviors), reduced energy expenditure, and accelerated and sustained weight gain, all of ...
Christian L. Roth   +11 more
doaj   +1 more source

Obesity Disrupts CtBP2‐Mediated Maintenance of Transcriptional Equilibrium in Hypothalamic Feeding Circuitry

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
CtBP2, a transcriptional corepressor with metabolite sensing capabilities, maintains feeding homeostasis by preventing excessive food intake in the hypothalamic feeding center. CtBP2 limits food intake by inhibiting KLF4 within AgRP neurons and by promoting the inhibitory influence of POMC neurons on AgRP neurons.
Wanpei Chen   +15 more
wiley   +1 more source

Resource allocation, hyperphagia and compensatory growth in juveniles [PDF]

open access: yes, 2003
Many organisms exploit highly variable food supplies and, as an adaptation to such conditions, show elevated growth during recovery from starvation.
Nisbet, Roy M.   +7 more
core   +1 more source

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

open access: yeseFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li   +13 more
wiley   +1 more source

Fiber degeneration associated with hyperphagia-inducing knife cuts in the hypothalamus [PDF]

open access: yes, 1980
The pattern of axonal degeneration associated with hyperphagia-producing hypothalamic knife transections was investigated using the Fink-Heimer method for staining of degenerating axons and their terminal endings.
Mufson, Elliott J.   +2 more
core   +1 more source

The Direct and Moderating Effect of Food Insecurity on Obesity—A Cross‐Sectional Study

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
This cross‐sectional study conducted in Türkiye investigated the direct and moderating effects of food insecurity on obesity prevalence. The findings reveal that food insecurity is associated with a graded increase in obesity rates: mild food insecurity raised obesity prevalence by 4.5%, moderate insecurity by 12%, and severe insecurity by 11.3 ...
Burak Mete   +5 more
wiley   +1 more source

Transcriptional Changes in Adipose Tissue Before and After the Onset of Hyperphagia in the Zucker (fa/fa) Rat [PDF]

open access: yes, 2005
The Zucker fatty (fa/fa) rat inherits a defective leptin receptor with impaired leptin signaling. Fatties grow at the same rate as their littermates for the first 22 days of age, and then suddenly begin to grow at a much higher rate.
Brown, Mary D.
core   +1 more source

A Role for Brain-Specific Homeobox Factor Bsx in the Control of Hyperphagia and Locomotory Behavior [PDF]

open access: yes, 2007
SummaryFood intake and activity-induced thermogenesis are important components of energy balance regulation. The molecular mechanism underlying the coordination of food intake with locomotory behavior to maintain energy homeostasis is unclear.
Ettwiller, L.   +15 more
core   +1 more source

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