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Hypothalamic hyperphagia prevented by prior subdiaphragmatic vagotomy: Insulin hyperphagia is unaffected

Physiology and Behavior, 1978
Abstract Male rats were given bilateral subdiaphragmatic vagotomy or a sham operation. Both groups of animals showed equivalent hyperphagia and weight gain during a ten day treatment with long-acting insulin. Despite this ability to increase feeding, the vagotomized rats did not overeat and become obese after VMH lesions.
Neil Rowland
exaly   +3 more sources

Analysis of diabetic hyperphagia and polydipsia

Physiology and Behavior, 1972
Abstract Diabetic hyperphagia is similar to experimental hyperphagia obtained by ventromedial hypothalamic lesions in that it is associated with motivational deficit and finickiness. On the other hand it is different in that diabetic hyperphagia is asymptotical while in the ventromedial hypothalamic lesioned animals hyperphagia subsides once obesity ...
L, Hernandez, E, Briese
exaly   +3 more sources

Hyperphagia and Down Syndrome

Journal of Developmental & Behavioral Pediatrics, 2023
CASE 1: A.Z. is a 14-year-old young boy with Down syndrome and intellectual disability. As a baby and toddler, A.Z. struggled with swallowing dysfunction and recurrent aspiration, which improved by the time he was school aged. At the age of 2 years, his body mass index (BMI) was 95.98% (Z score 1.75).
Aanchal Sharma   +2 more
openaire   +2 more sources

Hyperphagia in Bardet–Biedl syndrome: Pathophysiology, burden, and management [PDF]

open access: yesObesity Reviews
Summary Bardet–Biedl syndrome (BBS) is a rare, genetically heterogeneous, and highly pleiotropic autosomal recessive ciliopathy. Patients typically present with early loss of vision, hyperphagia, severe obesity, learning difficulties, and ...
Metin Cetiner   +2 more
exaly   +3 more sources

Defining Hyperphagia for Improved Diagnosis and Management of MC4R Pathway–Associated Disease: A Roundtable Summary [PDF]

open access: yesCurrent Obesity Reports
Purpose of review: Hyperphagia is a condition associated with rare obesity-related diseases, presenting as a pathologic, insatiable hunger accompanied by abnormal food-seeking behaviors.
Karine Clement, Steven Heymsfield
exaly   +2 more sources

Hypothalamic hyperphagia in the monkey.

Journal of Comparative and Physiological Psychology, 1964
The behavioral effects of lesions in the region of the ventromedial nuclei of the hypothalamus were studied in 7 monkeys. These Ss along with unoperated controls were utilized in various tests investigating parameters of food intake and weight gain; observations were made on the effects of the ...
C L, HAMILTON, J R, BROBECK
openaire   +2 more sources

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