Results 81 to 90 of about 18,942 (235)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart   +11 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Insulin Sensitivity and the Onset of Hyperphagia in Fatty Rats

open access: yes, 2004
Hyperphagia emerges suddenly after 22 days of age in Zucker fatty (fa/fa) rats, and fatties become visibly obese within days. This rapid increase in growth rate is likely to be associated with substantial changes in glucose metabolism. The objective of
Durham, Holiday Agnes
core  

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith   +2 more
wiley   +1 more source

Involvement of inflammatory gene expression pathways in depressed patients with hyperphagia

open access: yes, 2019
The pathophysiology of major depressive disorder (MDD) is highly heterogeneous. Previous evidence at the DNA level as well as on the serum protein level suggests that the role of inflammation in MDD pathology is stronger in patients with hyperphagia ...
de Kluiver, Hilde   +3 more
core   +1 more source

Kleine Levin syndrome – presentation of five cases

open access: yesIndian Journal of Psychiatry
Kleine Levin syndrome (KLS) is a rare entity. It presents with subacute onset episodic hypersomnia, cognitive decline, altered perception, and occasional hyperphagia and hypersexuality with full recovery during the interepisodic period.
Varaha Venkat Gantait   +3 more
doaj   +1 more source

Clinical and psychopathological features of depressions with panic attacks

open access: yesНеврология, нейропсихиатрия, психосоматика, 2017
Objective: to study the clinical and psychopathological features of depressions with panic attacks.Patients and methods. A total of 100 in- and outpatients aged 18 to 60 years, who had been treated in the S.S.
N. N. Ivanets   +3 more
doaj   +1 more source

Regimen‐dependent glucocorticoid effects improve muscle performance without altering CNS physiology in mdx mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Defining glucocorticoid efficacy in Duchenne muscular dystrophy requires assessment across muscle, central nervous system (CNS), cardiovascular and systemic domains. Here, juvenile mdx mice were treated over 6 weeks, comparing daily and weekly dosing of prednisolone and vamorolone.
Gretel S. Major   +4 more
wiley   +1 more source

Transient compulsive hyperphagia in a patient with a thalamic infarction

open access: yes, 2004
Eating disorders are associated with various psychiatric and neurological diseases. Pathological eating behaviour ranges from reduced to excessive appetite, dysregulation of hunger and satiation signals, and odd food preferences. Hyperphagia and anorexia
GRASSO M.   +9 more
core   +1 more source

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