Results 1 to 10 of about 27,643 (258)

Targeting Gastrointestinal Transport Proteins to Control Hyperphosphatemia in Chronic Kidney Disease [PDF]

open access: hybridDrugs, 2018
Management of hyperphosphatemia in patients with dialysis-dependent chronic kidney disease remains a major challenge, requiring a multifaceted approach that includes dietary phosphate restriction, dialysis, and phosphate binders.
Denis Fouque, Marc G Vervloet
exaly   +3 more sources

Protein and Phosphate Intakes are Associated with Hyperphosphatemia in Hemodialysis Patients at Sanglah Hospital, Bali, Indonesia [PDF]

open access: goldMajalah Kedokteran Bandung, 2022
Increased chronic kidney disease (CKD) mortality rate is significantly associated with increased blood phosphate levels. Hyperphosphatemia control is one of the main focuses in the management of hemodialysis (HD) patients.
Made Dyah Vismita Indramila Duarsa   +3 more
doaj   +2 more sources

Hyperphosphatemia and Outcomes in Critically Ill Patients: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Medicine, 2022
IntroductionSerum phosphate level is often deranged during critical illness. Hyperphosphatemia, as a marker of disease severity, attracts more and more attention.
Wen-He Zheng   +4 more
doaj   +2 more sources

Association between serum fibroblast growth factor‐23 concentration and development of hyperphosphatemia in normophosphatemic dogs with chronic kidney disease

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Fibroblast growth factor (FGF)‐23 is increased first in the sequence of changes associated with chronic kidney disease (CKD)‐mineral and bone disorder.
Hirosumi Miyakawa   +5 more
doaj   +2 more sources

Aging‐related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Hyperphosphatemia has been related to the development of sarcopenia in aging mice. We describe the intracellular mechanisms involved in the impairment of the myogenic differentiation promoted by hyperphosphatemia and analyse these mechanisms in the ...
Elena Alcalde-Estévez, Gemma Olmos
exaly   +2 more sources

Efficacy of DZ1462, a Novel Sodium-phosphate Transporter Inhibitor, on 5/6 Nephrectomy-induced Hyperphosphatemia Model Rats

open access: greenShiyan dongwu yu bijiao yixue, 2022
Objective To study the efficacy of DZ1462, a novel sodium-phosphate transporter inhibitor, on rat hyperphosphatemia models established by 5/6 nephrectomy.Methods Totally 156 rats were randomly selected into four groups.
LU Xiao   +3 more
doaj   +2 more sources

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia

open access: yesCellular and Molecular Life Sciences, 2019
Medial vascular calcification has emerged as a putative key factor contributing to the excessive cardiovascular mortality of patients with chronic kidney disease (CKD).
Jakob Voelkl   +2 more
exaly   +2 more sources

A Randomized Trial of Tenapanor and Phosphate Binders as a Dual-Mechanism Treatment for Hyperphosphatemia in Patients on Maintenance Dialysis (AMPLIFY)

open access: greenJournal of the American Society of Nephrology, 2021
Significance Statement In patients receiving maintenance dialysis, strategies for managing hyperphosphatemia are only moderately effective. In this 4-week randomized trial involving 236 patients experiencing hyperphosphatemia despite phosphate binder use,
Pablo E. Pérgola   +3 more
openalex   +3 more sources

Research status of dietary nursing intervention of hyperphosphatemia in hemodialysis patients (血液透析患者高磷血症饮食护理干预的研究现状)

open access: gold中西医结合护理, 2021
Hemodialysis patients are prone to hyperphosphatemia in the process of disease progression, which seriously reduce the patient’s quality of life. In clinical treatment and nursing, dietary nursing intervention can improve the prevention awareness of ...
WANG Liwei (王丽伟)   +4 more
doaj   +2 more sources

Hyperphosphatemia is associated with high mortality in severe burns. [PDF]

open access: yesPLoS ONE, 2018
Phosphate level is often deranged during acute illness, regardless of the presence of kidney injury or not. A few studies described that hypophosphatemia may associated with outcome in patients admitted to the burn unit, but the literatures for ...
George Kuo   +10 more
doaj   +2 more sources

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