Results 21 to 30 of about 25,820 (298)

Independent effects of secondary hyperparathyroidism and hyperphosphatemia on chronic kidney disease progression and cardiovascular events: an analysis from the NEFRONA cohort.

Nephrology, Dialysis and Transplantation, 2021
BACKGROUND Secondary hyperparathyroidism (SHPT) is a complication of chronic kidney disease (CKD), and it is associated with changes in calcium and phosphate.
M. Bozic, J. M. Díaz-Tocados, M. Bermúdez-López, C. Forné, Cristina Martínez, E. Fernández, J. Valdivielso   +6 more
semanticscholar   +1 more source

Association between phosphate disturbances and mortality among critically ill patients with sepsis or septic shock

BMC Pharmacology and Toxicology, 2021
Objective The aim of this study is to examine the association of hypophosphatemia and hyperphosphatemia on the first day of ICU admission with mortality in septic critically ill patients. Methods In this retrospective cohort study, all adult patients who
Shmeylan A. Al Harbi, Hasan M. Al-Dorzi, Albatool M. Al Meshari, Hani Tamim, Sheryl Ann I. Abdukahil, Musharaf Sadat, Yaseen Arabi   +6 more
doaj   +1 more source

Aging‐related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

Journal of Cachexia, Sarcopenia and Muscle, 2021
Hyperphosphatemia has been related to the development of sarcopenia in aging mice. We describe the intracellular mechanisms involved in the impairment of the myogenic differentiation promoted by hyperphosphatemia and analyse these mechanisms in the ...
Patricia Sosa, Elena Alcalde-Estévez, Ana Asenjo-Bueno, Patricia Plaza, N. Carrillo-López, G. Olmos, S. López-Ongil, M. Ruíz-Torres   +7 more
semanticscholar   +1 more source

Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2022
Background: There is limited evidence on the association of serum phosphate with mortality in patients receiving continuous renal replacement therapy (CRRT).
Charat Thongprayoon, Yeshwanter Radhakrishnan, Wisit Cheungpasitporn, Tananchai Petnak, Fawad Qureshi, Michael A. Mao, Kianoush B. Kashani   +6 more
doaj   +1 more source

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

bioRxiv, 2021
Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet.
Brian Czaya, K. Heitman, Isaac Campos, Christopher Yanucil, Dominik Kentrup, D. Westbrook, O. Gutiérrez, Jodie L Babitt, Grace Jung, I. Salusky, M. Hanudel, C. Faul   +11 more
semanticscholar   +1 more source

Evaluation of the cost-utility of phosphate binders as a treatment option for hyperphosphatemia in chronic kidney disease patients: a systematic review and meta-analysis of the economic evaluations

European Journal of Health Economics, 2021
Uncontrolled hyperphosphatemia in chronic kidney disease (CKD) patients commonly results in vascular calcification leading to increased risk of cardiovascular disease. Phosphate binders (PBs) are used for hyperphosphatemia and can be calcium-based (CBPBs)
Kamolpat Chaiyakittisopon, O. Pattanaprateep, Narisa Ruenroengbun, Tunlanut Sapankaew, A. Ingsathit, G. Mckay, J. Attia, A. Thakkinstian   +7 more
semanticscholar   +1 more source

Research Models for Studying Vascular Calcification [PDF]

, 2020
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen, Giet, Markus van der, Herrmann, Jaqueline, Schuchardt, Mirjam, Tölle, Markus   +4 more
core   +1 more source

Prevalence and factors associated with hyperphosphatemia in continuous ambulatory peritoneal dialysis patients: A cross-sectional study

Frontiers in Medicine, 2023
BackgroundHyperphosphatemia remains a major complication in patients with Continuous ambulatory peritoneal dialysis (CAPD) leading to increased morbidity and mortality. However, phosphorus management still has many challenges.ObjectiveThis study aimed to
Xiaojing Yin, Xiaojing Yin, Fan Zhang, Yan Shi   +3 more
doaj   +1 more source

EOS789, pan‐phosphate transporter inhibitor, ameliorates the progression of kidney injury in anti‐GBM‐induced glomerulonephritis rats

Pharmacology Research & Perspectives, 2022
Hyperphosphatemia associated with chronic kidney disease (CKD) not only dysregulates mineral metabolism and bone diseases, but also strongly contributes to the progression of kidney disease itself.
Yoshinori Tsuboi, Yasuhiro Ichida, Atsuko Murai, Akira Maeda, Manami Iida, Atsuhiko Kato, Shuichi Ohtomo, Naoshi Horiba   +7 more
doaj   +1 more source

Hyperphosphatemia is a complication of reduced kidney functions and limit for renoprotection

Počki, 2020
Hyperphosphatemia in patients with chronic kidney disease (CKD) is an important complication of impaired renal function and is associated with negative clinical consequences such as cardiovascular calcification, bone disease and secondary ...
S.V. Kushnirenko
doaj   +1 more source