Results 31 to 40 of about 27,643 (258)

Hyperphosphatemia and Cardiovascular Disease

Frontiers in Cell and Developmental Biology, 2021
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range” are highly associated with increased cardiovascular disease risk and mortality in the general population and patients suffering from chronic kidney disease (CKD).
Chao Zhou, Zhengyu Shi, Ouyang Nan, Xiongzhong Ruan   +3 more
semanticscholar   +1 more source

Both hypophosphatemia and hyperphosphatemia are associated with increased mortality in septic patients

Frontiers in Nephrology, 2022
Objective This study was intended to explore the relationship between level of serum phosphate and prognosis in septic patients. Methods Data were obtained from the public database, which were divided into 2 subgroups according to whether they were ...
Zheng-xia Liu, Teng Li, Yi Du, Chenhu Li, W. Chong   +4 more
semanticscholar   +1 more source

Association between phosphate disturbances and mortality among critically ill patients with sepsis or septic shock

BMC Pharmacology and Toxicology, 2021
Objective The aim of this study is to examine the association of hypophosphatemia and hyperphosphatemia on the first day of ICU admission with mortality in septic critically ill patients. Methods In this retrospective cohort study, all adult patients who
Shmeylan A. Al Harbi, Hasan M. Al-Dorzi, Albatool M. Al Meshari, Hani Tamim, Sheryl Ann I. Abdukahil, Musharaf Sadat, Yaseen Arabi   +6 more
doaj   +1 more source

Independent effects of secondary hyperparathyroidism and hyperphosphatemia on chronic kidney disease progression and cardiovascular events: an analysis from the NEFRONA cohort.

Nephrology, Dialysis and Transplantation, 2021
BACKGROUND Secondary hyperparathyroidism (SHPT) is a complication of chronic kidney disease (CKD), and it is associated with changes in calcium and phosphate.
M. Bozic, J. M. Díaz-Tocados, M. Bermúdez-López, C. Forné, Cristina Martínez, E. Fernández, J. Valdivielso   +6 more
semanticscholar   +1 more source

Association of Serum Phosphate Derangement With Mortality in Patients on Continuous Renal Replacement Therapy

Canadian Journal of Kidney Health and Disease, 2022
Background: There is limited evidence on the association of serum phosphate with mortality in patients receiving continuous renal replacement therapy (CRRT).
Charat Thongprayoon, Yeshwanter Radhakrishnan, Wisit Cheungpasitporn, Tananchai Petnak, Fawad Qureshi, Michael A. Mao, Kianoush B. Kashani   +6 more
doaj   +1 more source

Research Models for Studying Vascular Calcification [PDF]

, 2020
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen, Giet, Markus van der, Herrmann, Jaqueline, Schuchardt, Mirjam, Tölle, Markus   +4 more
core   +1 more source

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

bioRxiv, 2021
Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate-rich diet.
Brian Czaya, K. Heitman, Isaac Campos, Christopher Yanucil, Dominik Kentrup, D. Westbrook, O. Gutiérrez, Jodie L Babitt, Grace Jung, I. Salusky, M. Hanudel, C. Faul   +11 more
semanticscholar   +1 more source

Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia

American Journal of Nephrology, 2021
Introduction: Phosphate binders are used to treat hyperphosphatemia. Some patients have inappropriately controlled serum phosphorus levels, which may occur for many reasons, including a high pill burden and adverse events (AEs).
T. Shigematsu, Yotaro Une, Kazuaki Ikejiri, H. Kanda, M. Fukagawa, T. Akizawa   +5 more
semanticscholar   +1 more source

Prevalence and factors associated with hyperphosphatemia in continuous ambulatory peritoneal dialysis patients: A cross-sectional study

Frontiers in Medicine, 2023
BackgroundHyperphosphatemia remains a major complication in patients with Continuous ambulatory peritoneal dialysis (CAPD) leading to increased morbidity and mortality. However, phosphorus management still has many challenges.ObjectiveThis study aimed to
Xiaojing Yin, Xiaojing Yin, Fan Zhang, Yan Shi   +3 more
doaj   +1 more source

EOS789, pan‐phosphate transporter inhibitor, ameliorates the progression of kidney injury in anti‐GBM‐induced glomerulonephritis rats

Pharmacology Research & Perspectives, 2022
Hyperphosphatemia associated with chronic kidney disease (CKD) not only dysregulates mineral metabolism and bone diseases, but also strongly contributes to the progression of kidney disease itself.
Yoshinori Tsuboi, Yasuhiro Ichida, Atsuko Murai, Akira Maeda, Manami Iida, Atsuhiko Kato, Shuichi Ohtomo, Naoshi Horiba   +7 more
doaj   +1 more source