Results 61 to 70 of about 13,452 (217)

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin   +9 more
wiley   +1 more source

Fibroblast growth factor-23 (FGF-23) / soluble Klotho protein (sKlotho) / sclerostin glycoprotein ratio disturbance is a novel risk factor for cardiovascular complications in ESRD patients receiving treatment with regular hemodialysis or hemodiafiltration [PDF]

open access: yesТерапевтический архив, 2018
Aim of the study was to explore the role of the FGF-23/sKlotho/sclerostin ratio disturbance in the determining of cardiovascular risk in end stage renal disease (ESRD) patients, receiving treatment with regular hemodialysis (НD) or hemodiafiltration (НDF)
L Yu Milovanova   +7 more
doaj   +1 more source

Fatal Tumor Lysis Syndrome Induced by Pembrolizumab in Advanced Renal Pelvis Cancer

open access: yesIJU Case Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Tumor lysis syndrome (TLS) arises from the rapid breakdown of tumor cells during oncological treatment. Although TLS is rarely observed in solid tumors, few studies have documented instances of TLS associated with pembrolizumab. This report presents a case involving pembrolizumab‐induced TLS.
Takashi Asakura   +3 more
wiley   +1 more source

Blocking Sphingosine 1‐phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease

open access: yesJournal of Cellular Physiology, Volume 241, Issue 1, January 2026.
ABSTRACT Patients with chronic kidney disease, and particularly those under hemodialysis, are prone to develop cardiovascular complications, mostly due to the exacerbation of vascular calcification. Vascular calcification relies on the transdifferentiation of vascular smooth muscle cells into calcifying cells.
Najwa Skafi   +16 more
wiley   +1 more source

Unveiling Surfactant‐Coated Iron Oxide Nanoparticle Specifications for Enhancing Phosphate Removal in Peritoneal Dialysis‐Simulating Conditions

open access: yesSmall Structures, Volume 7, Issue 1, January 2026.
To enhance phosphate removal during peritoneal dialysis, a new dialysate formulation with designed surfactant‐coated iron oxide nanoparticles has been shown to be very effective through experiments in laboratory‐scale dialysis setups. Several transport mechanisms, including electrodiffusion and the Gibbs–Donnan effect, have been evidenced, providing ...
Théo Lucante   +4 more
wiley   +1 more source

Hypophosphatemia and Hyperphosphatemia

open access: yesCritical Care Clinics, 1991
Pathophysiology, clinical sequelae, and treatment for hypophosphatemia and hyperphosphatemia are discussed. Hypophosphatemia results from a variety of conditions including malnutrition, carbohydrate refeeding, acid-base disorders, and hormonal and drug effects. Patients suffering from severe hypophosphatemia may present with a variety of syndromes that
Michael P. Peppers   +2 more
openaire   +3 more sources

Midterm Outcome of AB0 Incompatible Kidney Transplantation in Children and Adolescents—A Single Center Experience

open access: yesPediatric Transplantation, Volume 30, Issue 1, January 2026.
AB0‐incompatible kidney transplantation in children can be performed with excellent results. Midterm outcome of AB0 incompatible KTx was not inferior to that of AB0 compatible KTx. Graft survival and graft function were comparably good in both groups. There was no increase in infectious complications or malignancies with AB0i KTx.
Christina Taylan   +4 more
wiley   +1 more source

Osteitis Fibrosa Cystica: An Unusual Cause of Left‐Sided Chest Pain

open access: yesCase Reports in Nephrology, Volume 2026, Issue 1, 2026.
We report a case of osteitis fibrosa cystica resulting from secondary hyperparathyroidism in a 21‐year‐old male patient with end‐stage renal disease. The patient presented with persistent, moderate chest pain localized to the left fifth and sixth ribs for eight months. A chest X‐ray revealed well‐defined, expansile lytic lesions in these ribs.
Raahima Habib   +4 more
wiley   +1 more source

Personalizing therapies over the course of hormone receptor‐positive/HER2‐negative metastatic breast cancer

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
ABSTRACT The hormone receptor (HR)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer subtype accounts for most early and metastatic breast cancer (MBC) cases. HR‐positive/HER2‐negative MBC is characterized by a relatively prolonged, although variable, disease course and substantial intertumoral and intratumoral ...
Akshara Singareeka Raghavendra   +5 more
wiley   +1 more source

High Phosphate Load Induces De Novo Formation of Tertiary Lymphoid Structures in the Kidney

open access: yesThe FASEB Journal, Volume 39, Issue 24, 31 December 2025.
Graphical illustration of renal alterations under varying phosphate load: High phosphate load induces fibrosis, tubular injury, impaired renal function, and de novo formation of perivascular tertiary lymphoid structures. Under normal phosphate load, fibrosis, functional decline, and tubular injury are absent, while T‐ and B‐ cell aggregates are present
Nina Weingärtner   +8 more
wiley   +1 more source

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