Results 91 to 100 of about 57,216 (335)

A practical guide to over‐the‐counter treatments for hyperpigmentation

JEADV Clinical Practice
Hyperpigmentation of the skin, defined as increased melanin in the epidermis, is a common condition associated with psychosocial impairment and decreased quality of life. Prescription options are often not covered by insurance and can be cost prohibitive.
Mustufa Jafry, Linna L. Guan, Tasneem F. Mohammad   +2 more
doaj   +1 more source

CUTANEOUS HYPERPIGMENTATION IN MEGALOBLASTIC ANEMIA: A FIVE YEAR RETROSPECTIVE REVIEW. [PDF]

, 2016
Background: Cutaneous hyperpigmentation is an often overlooked clinical sign in megaloblastic anemia (MA) which has been sporadically reported in the literature. Methods: We describe the bone marrow (BM) changes and clinicolaboaratory characteristics of
RajLaxmi Sarangi, Kandasamy Ravichandran, Sudhagar Mookkappan, Thomas Alexander, George Kurien, Somanath Padhi, Anita Ramdas, Renu G’Boy Varghese   +7 more
core   +1 more source

Itching for a diagnosis: Dysesthesias as an atypical presentation of Wilson disease in an adolescent—Case report

JPGN Reports, EarlyView.
Abstract Wilson disease (WD) is an autosomal recessive disorder of hepatic copper metabolism with varied clinical presentations. We describe a 15‐year‐old male referred for elevated aminotransferases, burning facial pruritis, scalp dysesthesias, and chronic bilateral lower extremity edema.
Tierra L. R. Mosher, John Hicks, Krupa R. Mysore   +2 more
wiley   +1 more source

Bleomycin-induced hyperpigmentation and hypersensitivity reactions to etoposide and vinblastine in a child with endodermal sinus tumor

The Turkish Journal of Pediatrics, 2001
We report a pediatric case who developed bleomycin-induced hyperpigmentation and hypersensitivity reactions to both etoposide and vinblastine while receiving chemotherapy for germ cell tumor.
K Mutafoğlu-Uysal, F Sarialioğlu, N Olgun   +2 more
doaj  

A case report of Peutz–Jeghers syndrome in a child with Crohn's disease

JPGN Reports, EarlyView.
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu, Eve May, Bethany Cunningham, Eric Cochran, Rachel Zdenek, Stefany H. Garrity   +5 more
wiley   +1 more source

Natural and Bioinspired Phenolic Compounds as Tyrosinase Inhibitors for the Treatment of Skin Hyperpigmentation: Recent Advances

Cosmetics, 2019
One of the most common approaches for control of skin pigmentation involves the inhibition of tyrosinase, a copper-containing enzyme which catalyzes the key steps of melanogenesis.
L. Panzella, A. Napolitano
semanticscholar   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Goras Georgios, Thrasyvoulou Andreas, Tsilimpokou Evanthia   +2 more
wiley   +1 more source

Hyperpigmentation due to pyrimethamine use

, 2002
Pyrimethamine is used for the treatment of tuxoplasmosis and the prophylaxis of malaria. Among the well-documented side effects are megaloblastic anemia, leukopenia, thrombopenia, rash, vomiting, and diarrhea. Hyperpigmentation is a very rare side effect.
Ozaras, Reşat, Tabak, F, Engin, A, Mert, A, Ozturk, R, Aktuglu, Y   +5 more
core   +1 more source

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni, Francois Rosset, Isotta Giunipero di Corteranzo, Lorenzo Bellando, Rebecca Senetta, Simone Ribero, Pietro Quaglino   +6 more
wiley   +1 more source

Thiamidol containing treatment regimens in facial hyperpigmentation: An international multi‐centre approach consisting of a double‐blind, controlled, split‐face study and of an open‐label, real‐world study

International Journal of Cosmetic Science, 2020
Tyrosinase is the rate‐limiting enzyme in melanogenesis. Thiamidol is the most potent inhibitor of human tyrosinase out of 50 000 tested compounds. In clinical studies, it was shown to improve facial hyperpigmentation, post‐inflammatory hyperpigmentation
W. Philipp-Dormston, A. V. Echag, erez Damonte, J. Riedel, A. Filbry, K. Warnke, C. Lofrano, D. Roggenkamp, G. Nippel   +8 more
semanticscholar   +1 more source