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Naunyn-Schmiedeberg's Archives of Pharmacology, 2023 20.500.12530/87908To describe a series of cases with pharmacological hyperprolactinemia in primary care setting and the prolactin levels, clinical implications of different causes of pharmacological hyperprolactinemia.
Marta Araujo Castro +2 more
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Pituitary, 2008
In several respects prolactin is unique among anterior pituitary hormones. The primary regulation of prolactin secretion is mediated through hypothalamic inhibition, and the diagnosis of hyperprolactinemia can be established without the use of stimulation or suppression tests.
Jaspreet, Chahal, Janet, Schlechte
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In several respects prolactin is unique among anterior pituitary hormones. The primary regulation of prolactin secretion is mediated through hypothalamic inhibition, and the diagnosis of hyperprolactinemia can be established without the use of stimulation or suppression tests.
Jaspreet, Chahal, Janet, Schlechte
openaire +3 more sources
Hyperprolactinemia: pathophysiology and therapeutic approach
Gynecological Endocrinology, 2015 Prolactin (PRL) is a hormone, mainly secreted by lactotroph cells of the anterior pituitary gland. Recent studies have shown it may also be produced by many extrapituitary cells.
Stefano Lello, Anna Capozzi
exaly +2 more sources
Importance of macroprolactinemia in hyperprolactinemia [PDF]
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2014 Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G. The term 'macroprolactinemia' is used when the concentration of macroprolactin exceeds 60% of the total serum prolactin concentration determined by polyethylene glycol precipitation.
Kasum, Miro +6 more
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Hyperprolactinemia and Impotence
Archives of Andrology, 1988One hundred impotent men and 15 sexually active male volunteers served as the source for this study. Serum prolactin was estimated in all cases using radioimmunoassay technique. Cases with hyperprolactinemia were treated with bromocriptine for 3 months.
A, el-Beheiry +4 more
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Pituitary, 2020
Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone.
di Filippo L. +3 more
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Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone.
di Filippo L. +3 more
openaire +3 more sources
Hyperprolactinemia and headaches
American Journal of Obstetrics and Gynecology, 1983We investigated the frequency of headaches in women with menstrual abnormalities and hyperprolactinemia. Twenty-seven of 46 (58%) women with hyperprolactinemia indicated that headache episodes occur once or more per week; patients with sellar abnormalities (macroadenoma) or previous cranial or pituitary operation were excluded from this group of ...
E, Kemmann, J R, Jones
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Galactorrhea and Hyperprolactinemia
Obstetrical & Gynecological Survey, 1983Galactorrhea refers to the secretion of a milky fluid from the breast occurring either spontaneously or with manual expression in the absence of pregnancy or the postpartum state. The development of a sensitive and specific radioimmunoassay for human prolactin during the last decade along with improved neuroradiologic techniques have greatly expanded ...
R, Sakiyama, M, Quan
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