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Importance of macroprolactinemia in hyperprolactinemia [PDF]
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2014 Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G. The term 'macroprolactinemia' is used when the concentration of macroprolactin exceeds 60% of the total serum prolactin concentration determined by polyethylene glycol precipitation.
Kasum, Miro +6 more
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Naunyn-Schmiedeberg's Archives of Pharmacology, 2023 20.500.12530/87908To describe a series of cases with pharmacological hyperprolactinemia in primary care setting and the prolactin levels, clinical implications of different causes of pharmacological hyperprolactinemia.
Ana M García Cano +2 more
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Pituitary, 2008
In several respects prolactin is unique among anterior pituitary hormones. The primary regulation of prolactin secretion is mediated through hypothalamic inhibition, and the diagnosis of hyperprolactinemia can be established without the use of stimulation or suppression tests.
Jaspreet, Chahal, Janet, Schlechte
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In several respects prolactin is unique among anterior pituitary hormones. The primary regulation of prolactin secretion is mediated through hypothalamic inhibition, and the diagnosis of hyperprolactinemia can be established without the use of stimulation or suppression tests.
Jaspreet, Chahal, Janet, Schlechte
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Hyperprolactinemia and Impotence
Archives of Andrology, 1988One hundred impotent men and 15 sexually active male volunteers served as the source for this study. Serum prolactin was estimated in all cases using radioimmunoassay technique. Cases with hyperprolactinemia were treated with bromocriptine for 3 months.
A, el-Beheiry +4 more
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Galactorrhea and Hyperprolactinemia
Obstetrical & Gynecological Survey, 1983Galactorrhea refers to the secretion of a milky fluid from the breast occurring either spontaneously or with manual expression in the absence of pregnancy or the postpartum state. The development of a sensitive and specific radioimmunoassay for human prolactin during the last decade along with improved neuroradiologic techniques have greatly expanded ...
R, Sakiyama, M, Quan
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Hyperprolactinemia and Infertility
Endocrinology and Metabolism Clinics of North America, 2011Prolactin-secreting pituitary tumors are a common cause of amenorrhea and infertility in premenopausal women. The goals of therapy are to normalize prolactin, restore gonadal function and fertility, and reduce tumor size, and dopamine agonists are the preferred therapy. Clinically significant tumor enlargement during pregnancy is uncommon and dependent
Amal, Shibli-Rahhal, Janet, Schlechte
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Hyperprolactinemia and headaches
American Journal of Obstetrics and Gynecology, 1983We investigated the frequency of headaches in women with menstrual abnormalities and hyperprolactinemia. Twenty-seven of 46 (58%) women with hyperprolactinemia indicated that headache episodes occur once or more per week; patients with sellar abnormalities (macroadenoma) or previous cranial or pituitary operation were excluded from this group of ...
E, Kemmann, J R, Jones
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Hyperprolactinemia in Sarcoidosis
Annals of Internal Medicine, 1972Abstract Serum prolactin levels were measured in 34 patients with extrapulmonary sarcoidosis (10 men, 24 women). Four patients had the syndrome of galactorrhea and amenorrhea.
R W, Turkington, J H, MacIndoe
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Treatments in Endocrinology, 2003
Hyperprolactinemia is commonly found in both female and male patients with abnormal sexual and/or reproductive function or with galactorrhea. If serum prolactin levels are above 200 microg/L, a prolactin-secreting pituitary adenoma (prolactinoma) is the underlying cause, but if levels are lower, differential diagnoses include the intake of various ...
Johan, Verhelst, Roger, Abs
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Hyperprolactinemia is commonly found in both female and male patients with abnormal sexual and/or reproductive function or with galactorrhea. If serum prolactin levels are above 200 microg/L, a prolactin-secreting pituitary adenoma (prolactinoma) is the underlying cause, but if levels are lower, differential diagnoses include the intake of various ...
Johan, Verhelst, Roger, Abs
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Hyperprolactinemia and Prolactinomas
Endocrinology and Metabolism Clinics of North America, 2008Any process interfering with dopamine synthesis, its transport to the pituitary gland, or its action at the level of lactotroph dopamine receptors can cause hyperprolactinemia. As described in this article, considering the complexity of prolactin regulation, many factors could cause hyperprolactinemia, and hyperprolactinemia can have clinical effects ...
MANCINI T +2 more
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