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Prolactin (PRL) is an anterior pituitary hormone which has its principle physiological action in initiation and maintenance of lactation. In human reproduction, pathological hyperprolactinemia most commonly presents as an ovulatory disorder and is often ...
Abha Majumdar, Nisha Sharma Mangal
doaj +4 more sources
Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone.
di Filippo L.+3 more
openaire +4 more sources
Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés+6 more
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Usefulness of prolactin levels in predicting the etiology of hyperprolactinemia in a cohort of 770 patients [PDF]
Objective Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of ...
Lucio Vilar+18 more
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Background: Hyperprolactinemia is a common finding in women of reproductive age that could result from physiological factors, pathological conditions or the use of different medications.
Ralitsa Robeva+4 more
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Relationship between prolactin plasma levels and white matter volume in women with multiple sclerosis [PDF]
BACKGROUND: The role of prolactin (PRL) on tissue injury and repair mechanisms in multiple sclerosis (MS) remains unclear. The aim of this work was to investigate the relationship between PRL plasma levels and brain damage as measured by magnetic ...
Barletta, VALERIA TERESA+10 more
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Research Progress of Plasma Cell Mastitis. [PDF]
ABSTRACT Background Plasma cell mastitis (PCM), also termed mammary duct ectasia, is a chronic nonbacterial inflammatory disease characterized by mammary duct dilation and plasma cell infiltration. Due to its varied and nonspecific clinical presentation, PCM is frequently misdiagnosed as breast cancer, complicating clinical management.
Liang Z, Zhang L.
europepmc +2 more sources
Hyperprolactinemia induced by hCG leads to metabolic disturbances in female mice [PDF]
The metabolic syndrome is a growing epidemic; it increases the risk for diabetes, cardiovascular disease, fatty liver, and several cancers. Several reports have indicated a link between hormonal imbalances and insulin resistance or obesity.
Bonaventura, Maria Marta+7 more
core +1 more source
Objective:We aimed to report the characteristics at admission, diagnosis, treatment, and follow-up of cases of pediatric hyperprolactinemia in a large multicenter study.Methods:We reviewed the records of 233 hyperprolactinemic patients, under 18 years of
Erdal Eren+29 more
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