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Risperidone Induced Hyperprolactinemia: From Basic to Clinical Studies

Frontiers in Psychiatry, 2022
Risperidone is one of the most commonly used antipsychotics (AP), due to its safety and efficacy in reducing psychotic symptoms. Despite the favorable side effect profile, the therapy is accompanied by side effects due to the non-selectivity of this ...
Milena Stojković, B. Radmanovic, M. Jovanovic, V. Janjić, Nemanja Murić, D. Ristic   +5 more
semanticscholar   +1 more source

Severe Hyperprolactinemia Promotes Brown Adipose Tissue Whitening and Aggravates High Fat Diet Induced Metabolic Imbalance

Frontiers in Endocrinology, 2022
Background The association of high serum prolactin and increased body weight is positive but controversial, therefore we hypothesized that additional factors such as diets and the impact of prolactin on brown adipose tissue may condition its metabolic ...
Felicitas Lopez-Vicchi, Catalina de Winne, A. Ornstein, E. Sorianello, J. Toneatto, D. Becu-Villalobos   +5 more
semanticscholar   +1 more source

Hyperprolactinemia as a side effect of using antipsychotics In Schizophrenic Patients

Jurnal Psikiatri Surabaya, 2023
Introductions: Antipsychotics are still the mainstay of schizophrenia management. Antipsychotics are antagonistic to postsynaptic dopamine receptors in the brain.
Syaiful Anwar, Khairina
doaj   +1 more source

Kisspeptin Overcomes GnRH Neuronal Suppression Secondary to Hyperprolactinemia in Humans

Journal of Clinical Endocrinology and Metabolism, 2022
Context Hyperprolactinemia suppresses gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone (LH) pulses. The hypothalamic neuropeptide kisspeptin potently stimulates the secretion of GnRH. The effects of exogenous kisspeptin administration on
Kateřina Hošková, N. Bryant, Margaret E. Chen, L. Nachtigall, Margaret F. Lippincott, Ravikumar Balasubramanian, S. Seminara   +6 more
semanticscholar   +1 more source

Hyperprolactinemia and insulin resistance.

Endokrynologia Polska, 2022
Hyperprolactinaemia is the most common dysfunction of the hypothalamic-pituitary axis and occurs more commonly in women. The prevalence of hyperprolactinaemia ranges from 0.4% in the general adult population to as high as 9-17% in women with reproductive
Marcin Gierach, Malwina Bruska-Sikorska, Magdalena Rojek, R. Junik   +3 more
semanticscholar   +1 more source

A case of hypogonadtropic hypogonadism due to hypophysitis discovered by secondary male infertility

IJU Case Reports, Volume 6, Issue 1, Page 51-53, January 2023., 2023
Introduction The main causes of secondary male infertility are varicocele and aging. It is rarely caused by adult‐onset hypopituitarism. The onset of hypopituitarism is often due to brain tumors, trauma, surgery, or congenital disorders. Case presentation A 29‐year‐old man was admitted to the hospital with complaints of decreased libido and semen ...
Masatoshi Konishi, Yoko Maegawa, Masaru Tani, Toshihisa Asakura, Yujiro Hayashi, Yoichi Kakuta, Koichi Tsutahara, Kazuhiko Komori, Tetsuya Takao   +8 more
wiley   +1 more source

Persistent bone impairment despite long-term control of hyperprolactinemia and hypogonadism in men and women with prolactinomas

Scientific Reports, 2021
While prolactinoma patients have high bone turnover, current data are inconclusive when it comes to determining whether correction of hyperprolactinemia and associated hypogandism improves osteodensitometric data in men and women over the long term. In a
L. Andereggen, J. Frey, R. Andres, M. Luedi, H. Widmer, J. Beck, L. Mariani, E. Christ   +7 more
semanticscholar   +1 more source

Hypoprolactinemia and hyperprolactinemia in male schizophrenia patients treated with aripiprazole and risperidone and their relationships with testosterone levels

Neuropsychopharmacology Reports, 2021
Several reports have shown that risperidone increases prolactin concentrations, while aripiprazole decreases prolactin concentrations. The frequency of abnormal prolactin concentrations in patients with schizophrenia receiving these drugs is still ...
Minami Tasaki, N. Yasui-Furukori, Saaya Yokoyama, M. Shinozaki, Norio Sugawara, K. Shimoda   +5 more
semanticscholar   +1 more source

Epidemiological and clinical profiles of Saudi patients with hyperprolactinemia in a single tertiary care center

Annals of Saudi Medicine, 2022
BACKGROUND: Prolactin is a hormone of the pituitary gland whose main function is the production of milk. Hyperprolactinemia is defined as an increase in prolactin levels above 25 μg/L in women and 20 μg/L in men.
Moeber Mahzari, Khalid Saad Alhamlan, Nawaf Abdulaziz Alhussaini, Turki Abdullah Alkathiri, Abdulmohsen Nasser Al Khatir, Abdulaziz Mohammed Alqahtani, Emad Fayez Masuadi   +6 more
doaj   +1 more source

Efficacy and safety in the treatment of hyperprolactinemia: A systematic review and network meta‐analysis

Journal of Clinical Pharmacy and Therapeutics, 2021
Hyperprolactinemia is a neuroendocrine disease that is responsible for a quarter of cases of secondary amenorrhea, which can lead to infertility in women.
M. Fachi, Lays de Deus Bueno, Denise Colaço de Oliveira, Letícia Lazarin da Silva, A. F. Bonetti   +4 more
semanticscholar   +1 more source