Results 41 to 50 of about 95,538 (286)

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

IMMEDIATE AND DELAYED HYPERSENSITIVITY REACTIONS TO PROTON PUMP INHIBITORS: A REVIEW ARTICLE [PDF]

Sanamed
Proton pump inhibitors (PPIs) are among the most widely prescribed medications in clinical practice, primarily used for managing acid-related gastrointestinal disorders. While generally regarded as safe, with adverse effects being rare and typically mild,
Corovic Vahida, Corovic Irfan, Ademovic Vahid, Gegic Altan, Dazdarevic Zecirovic Mirzeta, Corovic Kemal, Suljic Lejla, Corovic Licina Emina, Ziljkic Vahid, Plojovic Haris, Maksic Mladen, Dzankovic Fuad, Vucelj Samir, Suljic Muamer   +13 more
doaj   +1 more source

Immediate hypersensitivity to COVID-19 vaccines: Focus on biological diagnosis

Frontiers in Allergy, 2022
Soon after the release of the new anti-COVID mRNA vaccines, reports came in from the US and the UK of anaphylactic reactions. Fueled by the necessary caution toward these new vaccine platforms, these reports had a great impact and were largely commented ...
Pascale Nicaise-Roland, Pascale Nicaise-Roland, Vanessa Granger, Vanessa Granger, Angèle Soria, Angèle Soria, Annick Barbaud, Marc Pallardy, Sylvie Chollet-Martin, Sylvie Chollet-Martin, Luc de Chaisemartin, Luc de Chaisemartin   +11 more
doaj   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Hypersensitivity to Gadolinium-Based Contrast Media

Frontiers in Allergy, 2022
Gadolinium-based contrast agents (GBCAs) are frequently used in magnetic resonance imaging (MRI) examinations to increase sensitivity in diagnoses. Recently, an increase in the description of hypersensitivity reactions to GBCAs has been detected.
M. Teresa Gracia Bara, M. Teresa Gracia Bara, Alicia Gallardo-Higueras, Esther M. Moreno, Esther M. Moreno, Esther M. Moreno, Esther M. Moreno, Elena Laffond, Elena Laffond, Elena Laffond, Francisco J. Muñoz Bellido, Francisco J. Muñoz Bellido, Francisco J. Muñoz Bellido, Cristina Martin, Cristina Martin, Miriam Sobrino, Miriam Sobrino, Eva Macias, Eva Macias, Eva Macias, Sonia Arriba-Méndez, Sonia Arriba-Méndez, Sonia Arriba-Méndez, Rosita Castillo, Ignacio Davila, Ignacio Davila, Ignacio Davila, Ignacio Davila   +27 more
doaj   +1 more source

Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens [PDF]

, 2009
Delayed type hypersensitivity to natural rubber latex is rare compared to IgE mediated immediate reactions. Binding of allergens to MHC Class II is a crucial step in the presentation of antigens to CD4+ T Cells responsible for delayed reactions ...
Bell R. Eapen
core   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

The Time Delay Between Drug Intake and Bronchospasm for Nonsteroidal Antiinflammatory Drugs Sensitive Patients

World Allergy Organization Journal, 2010
A study was performed to assess the time between drug intake and drug induced hypersensitivity reaction for patients sensitive to nonsteroidal antiinflammatory drugs (NSAID) in clinical patient history and after oral provocation tests.
Giedre Grigiene, MD, Jolita Norkūnienė, PhD, Violeta Kvedariene, MD, PhD   +2 more
doaj   +1 more source

Chlorhexidine Hypersensitivity: A Case Report of Delayed Reactions Associated with Epidermal Preparations

Plastic and Reconstructive Surgery, Global Open, 2020
Summary:. Chlorhexidine is a topical antiseptic that is generally well tolerated in patients, making it a common preparatory substance in various surgical settings.
Priya Bhardwaj, MS, Jenna C. Bekeny, BA, Elizabeth G. Zolper, BS, Manas Nigam, MD, Sarah R. Sher, MD   +4 more
doaj   +1 more source

Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease [PDF]

, 2013
Background Aspirin-exacerbated respiratory disease is under-diagnosed and therefore effective and inexpensive therapy with aspirin desensitization is rarely performed.
Darby, Y, Gane, S, Larco, J, Miller, B, Mirakian, R, Sannah, AA, Scadding, G   +6 more
core   +1 more source